ChemicalBook >> CAS DataBase List >>1,3,5-Trihydroxy-4-prenylxanthone
1,3,5-Trihydroxy-4-prenylxanthone
- CAS No.
- 53377-61-0
- Chemical Name:
- 1,3,5-Trihydroxy-4-prenylxanthone
- Synonyms
- 5-Trihydroxy-4-prenylxanthone;1,3,5-Trihydroxy-4-prenylxanthone;1,3,5-Trihydroxy-4-(3-Methylbut-2-en-1-yl)-9H-xanthen-9-one;1,3,5-Trihydroxy-4-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one;9H-Xanthen-9-one, 1,3,5-trihydroxy-4-(3-methyl-2-buten-1-yl)-;1,3,5Trihydroxy4prenylxanthone,1,3,5 Trihydroxy 4 prenylxanthone
- CBNumber:
- CB52519192
- Molecular Formula:
- C18H16O5
- Molecular Weight:
- 312.32
- MDL Number:
- MFCD20260476
- MOL File:
- 53377-61-0.mol
- MSDS File:
- SDS
Last updated:2023-06-05 08:28:37
1,3,5-Trihydroxy-4-prenylxanthone Chemical Properties,Uses,Production
Description
1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM. 1,3,5-Trihydroxy-4-prenylxanthone inhibits LPS-induced NF-κB and AP-1 activations by interfering with the posttranslational modification (phosphorylation and/or ubiquitinylation) of IRAK-1 in the cell membrane to impede TAK1-mediated activation of IKK and MAPKs signal transduction. 3. 1,3,5-Trihydroxy-4-prenylxanthone shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 56.3plusmn;0.4 and 46.0plusmn;0.3 M, respectively.
target
NF-kB | IkB | AP-1 | JNK | ERK | TGF-β/Smad | AChR | IKK
Synthesis of 1,3,5-Trihydroxy-4-prenylxanthone from 1,3,5-Trihydroxyxanthone and 3,3-Dimethylallyl bromide
1,3,5-Trihydroxy-4-prenylxanthone Preparation Products And Raw materials
Raw materials
Preparation Products
1,3,5-Trihydroxy-4-prenylxanthone Suppliers
Global( 31)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3632 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 | peter68@ptchemgroup.com | China | 35453 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5654 | 65 |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2993 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
View Lastest Price from 1,3,5-Trihydroxy-4-prenylxanthone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-20 | 1,3,5-Trihydroxy-4-prenylxanthone
53377-61-0
|
US $0.00-0.00 / KG | 5mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd |
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- 1,3,5-Trihydroxy-4-prenylxanthone
53377-61-0
- US $0.00-0.00 / KG
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
53377-61-0(1,3,5-Trihydroxy-4-prenylxanthone)Related Search:
1,3,5-Trihydroxy-4-prenylxanthone
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53377-61-0