5alpha-Hydroxycostic acid
- CAS No.
- 132185-83-2
- Chemical Name:
- 5alpha-Hydroxycostic acid
- Synonyms
- 5α-Hydroxycosticacid;5α-Hydroxycostic acid;5alpha-Hydroxycostic acid;2-Naphthaleneacetic acid, decahydro-8a-hydroxy-4a-methyl-α,8-bis(methylene)-, (2R,4aR,8aR)-;(2R,4aR,8aR)-Decahydro-8a-hydroxy-4a-methyl-alpha,8-bis(methylene)-2-naphthaleneacetic acid
- CBNumber:
- CB52519455
- Molecular Formula:
- C15H22O3
- Molecular Weight:
- 250.33338
- MDL Number:
- MFCD20260447
- MOL File:
- 132185-83-2.mol
5alpha-Hydroxycostic acid Chemical Properties,Uses,Production
Uses
5α-Hydroxycostic acid, a eudesmane-type sesquiterpene, is isolated from the herb Laggera alata. 5α-Hydroxycostic acid inhibits angiogenesis and suppresses breast cancer cell migration through regulating VEGF/VEGFR2 and Ang2/Tie2 pathways[1].
target
VEGF | Src | AKT | NOS | FAK | PLCγ | ERK
References
[1] Liang N, et, al. Two natural eudesmane-type sesquiterpenes from Laggera alata inhibit angiogenesis and suppress breast cancer cell migration through VEGF- and Angiopoietin 2-mediated signaling pathways. Int J Oncol. 2017 Jul;51(1):213-222. DOI:10.3892/ijo.2017.4004
5alpha-Hydroxycostic acid Preparation Products And Raw materials
Raw materials
Preparation Products
5alpha-Hydroxycostic acid Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30231 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
Mensura Group Limited | +8618109034517 | 1058503172@qq.com | China | 2900 | 58 |
BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5653 | 65 |
Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15178 | 58 |
Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8144 | 55 |