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DISIALOGANGLIOSIDE GD1B 2NA

CAS No.
19553-76-5
Chemical Name:
DISIALOGANGLIOSIDE GD1B 2NA
Synonyms
Gd1b;GD1B 2NA;Aids002546;Aids-002546;Ganglioside G2;Ganglioside C1;Ganglioside giii;GD1B-GANGLIOSIDE;GD1B (NH4+ SALT);ganglioside, GD1b
CBNumber:
CB5253296
Molecular Formula:
C84H148N4O40
Molecular Weight:
1854.08
MDL Number:
MFCD00466941
MOL File:
19553-76-5.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:09

DISIALOGANGLIOSIDE GD1B 2NA Properties

storage temp. −20°C
solubility Chloroform:Methanol:DI Water (2:1:0.1): soluble
form lyophilized powder

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Safety Statements  22-24/25
WGK Germany  3
10-21
HS Code  29400090
NFPA 704
0
2 0

DISIALOGANGLIOSIDE GD1B 2NA price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich G8146 Disialoganglioside GD1b from bovine brain ~95% 19553-76-5 1mg $313 2024-03-01 Buy
Cayman Chemical 19569 Ganglioside GD1b (sodium salt) ≥98% 19553-76-5 1mg $141 2024-03-01 Buy
Usbiological 297011 GD1b-Ganglioside 19553-76-5 1mg $523 2021-12-16 Buy
TRC G235073 GangliosideGD1bDisodiumSalt(BovineBrain) 19553-76-5 1mg $560 2021-12-16 Buy
Biosynth Carbosynth OG175968 GD1b-Ganglioside ammonium 19553-76-5 2mg $770 2021-12-16 Buy
Product number Packaging Price Buy
G8146 1mg $313 Buy
19569 1mg $141 Buy
297011 1mg $523 Buy
G235073 1mg $560 Buy
OG175968 2mg $770 Buy

DISIALOGANGLIOSIDE GD1B 2NA Chemical Properties,Uses,Production

Description

Ganglioside GD1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside GD1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside GD1b levels are positively correlated with pilocytic astrocytoma tumor grade, and GD1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas. Ganglioside GD1b mixture contains ganglioside GD1b molecular species with C18:1 and C20:1 fatty acyl chains.

Uses

Ganglioside GD1b Disodium Salt (Bovine Brain) is a ganglioside, major constituents of neuronal cell membranes and endoplasmic reticulum that have been shown to modulate cell signal transduction.

General Description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Biochem/physiol Actions

May act as a bacterial toxin receptor (tetanus, botulinus); high levels found in gliomas and astrocytomas.

DISIALOGANGLIOSIDE GD1B 2NA Preparation Products And Raw materials

Raw materials

Preparation Products

DISIALOGANGLIOSIDE GD1B 2NA Suppliers

Global( 55)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
GlycoPharm.LLC
+86-27-63498076 sale@glycolipidpharm.com CHINA 158 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Shanghai Tauto Biotech Co., Ltd. 021-51320588 tauto@tautobiotech.com China 3989 66
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1976 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58

View Lastest Price from DISIALOGANGLIOSIDE GD1B 2NA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide                Synonym:?GD1b pictures 2020-03-26 Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide Synonym:?GD1b
19553-76-5
US $0.00 / test 5test 97%HPLC MG-KG GlycoPharm.LLC
Ganglioside GD1b, Disialo, Diammonium Salt, Bovine Brain ganglioside gd1b, disialo GANGLIOSIDEGD1BDISODIUMSALT,BOVINEBRAIN ganglioside, GD1b Aids002546 Aids-002546 Ganglioside C1 Ganglioside G2 Ganglioside G2 (hexasaccharide) Ganglioside gd1B polysaccharide Ganglioside giii Gd1b GAL-BETA1,3GALNAC-BETA1,4(NEU5AC-ALPHA2,8)(NEU5AC-ALPHA2,3)GAL-BETA1,1' CERAMIDE GALBETA1,3GALNACBETA1,4(NEU5ACALPHA2,8)(NEU5ACALPHA2,3)GALBETA1-4GLCBETA1,1' CERAMIDE GAL-BETA1,3GALNAC-BETA1,4(NEU5AC-ALPHA2,8)(NEU5AC-ALPHA2,3)GAL-BETA1-4GLC-BETA1,1' CERAMIDE, HUMAN GANGLIOSIDE GD1B, DISIALO, DIAMMONIUM SALT, BOVINE GANGLIOSIDE GD1B, DISIALO, HUMAN GANGLIOSIDE GD1B, DISIALO, HUMAN BRAIN GANGLIOSIDE GD1B DISODIUM SALT GD1B 2NA GD1B-GANGLIOSIDE GD1B (NH4+ SALT) II3(NEU5AC)2GGOSE4 CERAMIDE, 2NH4, BOVINE II3(NEU5NAC)2GGOSE4 CERAMIDE II3(NEU5NAC)2GGOSE4 CERAMIDE, HUMAN II3(NEUAC)2-GGOSE4CER DISIALOGANGLIOSIDE-GD1B DISIALOGANGLIOSIDE GD1B 2NA Ganglioside GD1b (sodium salt) DISIALOGANGLIOSIDE GD1B, BOVINE DISIALOGANGLIOSIDE GD1B, HUMAN DISIALOGANGLIOSIDE GD1B (NH4+ SALT) MONOSIALOGANGLIOSIDE GD1B DISODIUM SALT disialoganglioside G(D1B) from bovine brain beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer GD1b-Ganglioside sodium Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide Synonym:GD1b Ganglioside GD1b Mixture (sodium salt) GD1b ganglioside disodium salt (bovine brain) Neu5Acα2, 8Neu5Acα2, 3(Galβ1, 3GalNAcβ1, 4)Galβ1, 4Glc Ceramide Ganglioside GD1b Mixture (porcine brain) (ammonium salt) 19553-76-5 C67H113N4O39R