ChemicalBook >> CAS DataBase List >>1,3-Dichloro-4-fluorobenzene

1,3-Dichloro-4-fluorobenzene

CAS No.
1435-48-9
Chemical Name:
1,3-Dichloro-4-fluorobenzene
Synonyms
2,4-DICHLORO-1-FLUOROBENZENE;2,4-DICHLOROFLUOROBENZENE;2,4-Dichlorofluorobenzene 99%;2,4-Dichloro-1-fluor;2,4-Dichlorofluobenzene;1,3-DICHLOROFLUOROBENZENE;2,4- twochlorofluorobenzene;2,4-Dichlorofluorobenzene99%;1,3-DICHLORO-4-FLUOROBENZENE;2,4-Dichlorofluorobenzene>
CBNumber:
CB5257704
Molecular Formula:
C6H3Cl2F
Molecular Weight:
164.99
MDL Number:
MFCD00000580
MOL File:
1435-48-9.mol
MSDS File:
SDS
Last updated:2025-09-26 17:40:57
Product description Number Pack Size Price
2,4-Dichlorofluorobenzene >96.0%(GC) D2059 25g $29
2,4-Dichlorofluorobenzene >96.0%(GC) D2059 500g $214
2,4-Dichlorofluorobenzene D438810 2.5g $75
2,4-Dichlorofluorobenzene 98% 1600-7-04 100g $96
1,3-dichloro-4-fluorobenzene FD104751 500g $600
More product size

1,3-Dichloro-4-fluorobenzene Properties

Melting point -23 °C
Boiling point 172-174 °C(lit.)
Density 1.409 g/mL at 25 °C(lit.)
refractive index n20/D 1.525(lit.)
Flash point 98 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Colorless to Light yellow to Light orange
Specific Gravity 1.409
Water Solubility insoluble
BRN 2500791
InChI InChI=1S/C6H3Cl2F/c7-4-1-2-6(9)5(8)3-4/h1-3H
InChIKey BDJZCCWUSOZUQG-UHFFFAOYSA-N
SMILES C1(F)=CC=C(Cl)C=C1Cl
CAS DataBase Reference 1435-48-9(CAS DataBase Reference)
EWG's Food Scores 1-2
NIST Chemistry Reference 1,3-Dichloro-4-fluorobenzene(1435-48-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07,GHS09,GHS08
Signal word  Warning
Hazard statements  H226-H302-H315-H411-H227-H373
Precautionary statements  P210-P233-P240-P241+P242+P243-P264-P270-P273-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P391-P403+P235-P501-P210e-P260-P280a-P301+P312a-P501a
Hazard Codes  Xn,N,Xi
Risk Statements  22-38-48/20/22-51/53-10-36/37/38
Safety Statements  36/37-61-16-36-26
RIDADR  UN 1993 3/PG 3
WGK Germany  3
Hazard Note  Irritant
HazardClass  9
PackingGroup  III
HS Code  29039990
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
2 0

1,3-Dichloro-4-fluorobenzene price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D2059 2,4-Dichlorofluorobenzene >96.0%(GC) 1435-48-9 25g $29 2025-07-31 Buy
TCI Chemical D2059 2,4-Dichlorofluorobenzene >96.0%(GC) 1435-48-9 500g $214 2025-07-31 Buy
TRC D438810 2,4-Dichlorofluorobenzene 1435-48-9 2.5g $75 2021-12-16 Buy
SynQuest Laboratories 1600-7-04 2,4-Dichlorofluorobenzene 98% 1435-48-9 100g $96 2021-12-16 Buy
Biosynth Carbosynth FD104751 1,3-dichloro-4-fluorobenzene 1435-48-9 500g $600 2021-12-16 Buy
Product number Packaging Price Buy
D2059 25g $29 Buy
D2059 500g $214 Buy
D438810 2.5g $75 Buy
1600-7-04 100g $96 Buy
FD104751 500g $600 Buy

1,3-Dichloro-4-fluorobenzene Chemical Properties,Uses,Production

Chemical Properties

Clear colourless to yellow liquid

Uses

1, 3-dichloro-4-fluorobenzene is a multifunctional chemical reagent. Its benzene ring structure formula contains fluorine and chlorine functional groups and can be used in various reaction systems. It is widely applied in the field of organic synthesis.

Synthesis

3-Chloro-4-fluoronitrobenzene

350-30-1

1,3-Dichloro-4-fluorobenzene

1435-48-9

The general procedure for the synthesis of 2,4-dichlorofluorobenzene from 3-chloro-4-fluoronitrobenzene is as follows: 240 g (1.37 mol) of 3-chloro-4-fluoronitrobenzene was added to a 250 ml four-necked flask and the temperature of the reaction system was raised to 170°C. The temperature of the reaction system was raised to 170°C. The reaction system was then purged with dry chlorine. Dry chlorine gas was slowly passed in the temperature range of 170 to 180 °C. The reaction process was carried out by distillation for 8 hours and the distillate was collected. The distillate was subsequently washed with water and then with alkali to a weakly basic pH. The organic phase was separated and purified by distillation, resulting in 207 g of 2,4-dichlorofluorobenzene with 99.8% purity and 91.7% yield.

References

[1] Patent: CN102249881, 2016, B. Location in patent: Paragraph 0020; 0075-0076
[2] Recueil des Travaux Chimiques des Pays-Bas, 1932, vol. 51, p. 98,109

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View Lastest Price from 1,3-Dichloro-4-fluorobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3-Dichloro-4-fluorobenzene pictures 2025-11-10 1,3-Dichloro-4-fluorobenzene
1435-48-9
US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
1,3-Dichloro-4-fluorobenzene pictures 2025-09-26 1,3-Dichloro-4-fluorobenzene
1435-48-9
US $0.00 / KG 1KG 99% 50000KG/month Sichuan Zhuoyu Yantang Technology Co., Ltd.
1,3-Dichloro-4-fluorobenzene pictures 2025-09-25 1,3-Dichloro-4-fluorobenzene
1435-48-9
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2,4-Dichlorofluorobenzene99% DCFB 2,4-Dichlorofluorobenzen 1,3-Dichloro-4-fluorobenzene,99% 2,4-DICHLOROFLUOROBENZENECIPROFLOXACIN 2,4-Dichloro-1-fluor 2,4-Dichlorofluobenzene 2,4- twochlorofluorobenzene Benzene,2,4-dichloro-1-fluoro- 2,4-DichloroFluorobenzene99.5% 1,3-DICHLORO-4-FLUOROBENZENE 1,3-DICHLOROFLUOROBENZENE N-[4-(trichloromethylthio)sulfonylphenyl]acetamide 2,4-Dichlorofluorobenzene> 1,3-Dichloro-4-fluorobenzene ISO 9001:2015 REACH 2,4-Dichlorofluorobenzene 99% 2,4-DICHLORO-1-FLUOROBENZENE 2,4-DICHLOROFLUOROBENZENE 1435-48-9 1435-38-9 Aryl Building Blocks Organic Building Blocks Halogenated Hydrocarbons C6 Aromatic Hydrocarbons (substituted) & Derivatives Fluorobenzene Chlorine Compounds Fluorine Compounds Aryl Halogenated Hydrocarbons bc0001 OLED C6