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1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-

1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Structure
1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- structure
CAS No.
478082-99-4
Chemical Name:
1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-
Synonyms
Ro4368554;7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole;3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole;1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)-
CBNumber:
CB52606566
Molecular Formula:
C19H21N3O2S
Molecular Weight:
355.45
MDL Number:
MFCD16875430
MOL File:
478082-99-4.mol
MSDS File:
SDS
Last updated:2023-05-04 15:11:42
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1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Properties

Melting point 160-162 °C
Boiling point 596.8±50.0 °C(Predicted)
Density 1.299±0.06 g/cm3(Predicted)
storage temp. room temp
solubility DMSO: >10mg/mL
pka 15.49±0.30(Predicted)
form powder
color off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  2

1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R8782 Ro4368554 ≥98% (HPLC) 478082-99-4 5mg $197 2022-05-15 Buy
Sigma-Aldrich R8782 Ro4368554 ≥98% (HPLC) 478082-99-4 25mg $759 2022-05-15 Buy
Usbiological 464796 Ro4368554 478082-99-4 5mg $403 2021-12-16 Buy
TRC R700880 Ro4368554 478082-99-4 10mg $185 2021-12-16 Buy
American Custom Chemicals Corporation API0008409 RO4368554 95.00% 478082-99-4 10MG $619.72 2021-12-16 Buy
Product number Packaging Price Buy
R8782 5mg $197 Buy
R8782 25mg $759 Buy
464796 5mg $403 Buy
R700880 10mg $185 Buy
API0008409 10MG $619.72 Buy

1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Chemical Properties,Uses,Production

Uses

Ro4368554 is a selective 5-Hydroxytryptamine 6 (5-HT6) receptor antagonists.

Biochem/physiol Actions

Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).

1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Sigma-Aldrich 80
Energy Chemical 58
1H-Indole, 7-(4-Methyl-1-piperazinyl)-3-(phenylsulfonyl)- 3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole 7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole Ro4368554 478082-99-4