ChemicalBook >> CAS DataBase List >>BAY 80-6946 (Copanlisib)
BAY 80-6946 (Copanlisib)
- CAS No.
- 1032568-63-0
- Chemical Name:
- BAY 80-6946 (Copanlisib)
- Synonyms
- Copanlisib;BAY80-6946;CS-2321;Aliqopa);Copanlisib base;Copanlisib free base;Copanlisib(BAY80-6946);BAY 80-6946 (BAY80-6946;BAY 80-6946 (Copanlisib);BAY 80-6946 (Copanlisib) USP/EP/BP
- CBNumber:
- CB52616024
- Molecular Formula:
- C23H28N8O4
- Molecular Weight:
- 480.52
- MDL Number:
- MFCD18633201
- MOL File:
- 1032568-63-0.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:46
| Density | 1.51 |
|---|---|
| storage temp. | Store at -20°C |
| solubility | insoluble in DMSO; insoluble in H2O; insoluble in EtOH |
| form | solid |
| pka | 8.42±0.20(Predicted) |
| FDA UNII | WI6V529FZ9 |
| ATC code | L01EM02 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
BAY 80-6946 (Copanlisib) price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20354 | Copanlisib ≥98% | 1032568-63-0 | 5mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 20354 | Copanlisib ≥98% | 1032568-63-0 | 1mg | $72 | 2023-06-20 | Buy |
| Cayman Chemical | 20354 | Copanlisib ≥98% | 1032568-63-0 | 10mg | $91 | 2024-03-01 | Buy |
| TRC | B119060 | BAY80-6946 | 1032568-63-0 | 10mg | $395 | 2021-12-16 | Buy |
| ChemScene | CS-0741 | Copanlisib 98.91% | 1032568-63-0 | 100mg | $450 | 2021-12-16 | Buy |
BAY 80-6946 (Copanlisib) Chemical Properties,Uses,Production
Uses
BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models.
Definition
ChEBI: Copanlisib is an imidazoquinazoline that is 2,3-dihydroimidazo[1,2-c]quinazoline substituted by (2-aminopyrimidine-5-carbonyl)amino, methoxy, and 3-(morpholin-4-yl)propoxy groups at positions 5, 7 and 8, respectively. It is a intravenous pan-class I PI3K inhibitor used for the treatment of relapsed follicular lymphoma in patients who have received at least 2 prior systemic therapies. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a member of morpholines, an aromatic ether, a diether, a tertiary amino compound, a secondary carboxamide, a pyrimidinecarboxamide, an aminopyrimidine and an imidazoquinazoline.
BAY 80-6946 (Copanlisib) Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 147)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29474 | 58 |
View Lastest Price from BAY 80-6946 (Copanlisib) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | BAY 80-6946 (Copanlisib)
1032568-63-0
|
US $2.00 / kg | 1kg | 99% | 100kg | Career Henan Chemical Co |
-
- BAY 80-6946 (Copanlisib)
1032568-63-0
- US $2.00 / kg
- 99%
- Career Henan Chemical Co
1032568-63-0(BAY 80-6946 (Copanlisib))Related Search:
2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide
5-Pyrimidinecarboxamide, 2-amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-
Copanlisib(BAY80-6946)
BAY 80-6946 (Copanlisib)
7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine
Aliqopa)
BAY 80-6946 (Copanlisib) USP/EP/BP
Copanlisib free base
BAY 80-6946; BAY80-6946; BAY-80-6946; BAY806946; BAY-806946; BAY 806946; COPANLISIB FREE BASE
CS-2321
BAY 80-6946 (BAY80-6946
Copanlisib base
Copanlisib, 98%, an ATP-competitive selective class-I PI3 kinases inhibitor
BAY80-6946
Copanlisib
2-Amino-N-(7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)pyrimidine-5-carboxamide
1032568-63-0
C23H28N8O4
Inhibitors
Akt
mTOR
PI3K
PI3K/Akt/mTOR