HexadecanaMide, N-(phenylMethyl)-
- CAS No.
- 74058-71-2
- Chemical Name:
- HexadecanaMide, N-(phenylMethyl)-
- Synonyms
- N-benzylpalMitaMide;N-Benzylhexadecanamide;Macamide B;Macamide 1;Macamide Impurity 4;Hexadecanamide, N-benzyl-;Macamide B, Macamide Impurity 1;HexadecanaMide, N-(phenylMethyl)-
- CBNumber:
- CB52640001
- Molecular Formula:
- C23H39NO
- Molecular Weight:
- 345.56
- MDL Number:
- MFCD00378779
- MOL File:
- 74058-71-2.mol
- MSDS File:
- SDS
| Melting point | 95-96℃ |
|---|---|
| Boiling point | 501.9±29.0 °C(Predicted) |
| Density | 0.919±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ≤2mg/ml in organic solvent ethanol |
| form | crystalline solid |
| pka | 16.39±0.46(Predicted) |
| FDA UNII | 1M5UVS8JUU |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
HexadecanaMide, N-(phenylMethyl)- price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 9002235 | N-Benzylpalmitamide ≥98% | 74058-71-2 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 9002235 | N-Benzylpalmitamide ≥98% | 74058-71-2 | 10mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 9002235 | N-Benzylpalmitamide ≥98% | 74058-71-2 | 50mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 9002235 | N-Benzylpalmitamide ≥98% | 74058-71-2 | 100mg | $305 | 2024-03-01 | Buy |
| Usbiological | 361823 | Macamide B | 74058-71-2 | 10mg | $439 | 2021-12-16 | Buy |
HexadecanaMide, N-(phenylMethyl)- Chemical Properties,Uses,Production
Uses
N-Benzyl Hexadecanamide is a non-?polar, long-?chain fatty acid N-?benzylamide part of a group of macamides tested as potential inhibitors of the human enzyme, fatty acid amide hydrolase (FAAH)?.
Definition
ChEBI: N-benzylhexadecanamide is a macamide resulting from the formal condensation of the carboxy group of hexadecanoic acid with benzylamine. A moderate inhibitor of fatty acid amide hydrolase. It has a role as a neuroprotective agent, a plant metabolite and an EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor. It is a secondary carboxamide and a macamide. It is functionally related to a hexadecanoic acid and a benzylamine.
Biological Activity
n-benzylpalmitamide is an inhibitor of fatty acid amide hydrolase (faah) [1].the fatty acid amide hydrolase (faah) is a mammalian integral membrane enzyme responsible for the hydrolysis of anandamide, an endocannabinoid. the faah is involved in degrading the fatty acid amide family of endogenous signaling lipids, including the endogenous cannabinoid anandamide and the sleep-inducing substance oleamide. faah belongs to is a member of amidase signature (as) family. the faah integrates into cell membranes and terminates fatty acid amide signaling in vivo [2]. genetic mutations in faah may constitute important risk factors for problem drug use and support a potential link between functional abnormalities in the endogenous cannabinoid system and drug abuse and dependence [3].n-benzylpalmitamide was a long-chain fatty acid amide isolated from the maca (l. meyenii) plant and was structurally related to cannabinoids. n-benzylpalmitamide was a moderate inhibitor of faah and inhibited 44% activity of faah at 500 μm [1].
References
[1] wu h, kelley c j, pino-figueroa a, et al. macamides and their synthetic analogs: evaluation of in vitro faah inhibition[j]. bioorganic & medicinal chemistry, 2013, 21(17): 5188-5197.
[2] deutsch d g, ueda n, yamamoto s. the fatty acid amide hydrolase (faah)[j]. prostaglandins, leukotrienes and essential fatty acids (plefa), 2002, 66(2): 201-210.
[3] sipe j c, chiang k, gerber a l, et al. a missense mutation in human fatty acid amide hydrolase associated with problem drug use[j]. proceedings of the national academy of sciences, 2002, 99(12): 8394-8399.
HexadecanaMide, N-(phenylMethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
View Lastest Price from HexadecanaMide, N-(phenylMethyl)- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-09 | Macamide B
74058-71-2
|
US $0.00 / g | 5g | 98% | 20000 | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2023-02-24 | N-benzylpalmitamide
74058-71-2
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2020-01-13 | HexadecanaMide, N-(phenylMethyl)-
74058-71-2
|
US $5.50 / KG | 1KG | 98%min | 1kg-100kg | Career Henan Chemical Co |
-
- Macamide B
74058-71-2
- US $0.00 / g
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- N-benzylpalmitamide
74058-71-2
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- HexadecanaMide, N-(phenylMethyl)-
74058-71-2
- US $5.50 / KG
- 98%min
- Career Henan Chemical Co