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ChemicalBook >> CAS DataBase List >>4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Structure
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline structure
CAS No.
190728-25-7
Chemical Name:
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
Synonyms
Benzenam;4-(6,7-Dimethoxy-quinoL;Cabozantinib Amine Analog;Intermediate 1 of Cabozantinib;Cabozantinib Genotoxic Impurity I;4-[(6,7-dimethoxy-4-quinolinyl)oxy]-;4-(6,7-dimethoxy quinolinoxy) aniline;4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline;6,7-Dimethoxy-4-(4-aminophenoxy)quinoline;4-(4-Aminophenoxy)-6,7-dimethoxyquinoline
CBNumber:
CB52652846
Molecular Formula:
C17H16N2O3
Molecular Weight:
296.32
MDL Number:
MFCD19685633
MOL File:
190728-25-7.mol
MSDS File:
SDS
Last updated:2023-12-26 17:07:23
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4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Properties

Melting point 211.0 to 215.0 °C
Boiling point 481.8±45.0 °C(Predicted)
Density 1.246±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
form powder to crystal
pka 6.79±0.30(Predicted)
color Light yellow to Brown
InChI InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-8-7-15(13)22-12-5-3-11(18)4-6-12/h3-10H,18H2,1-2H3
InChIKey VXEQRXJATQUJSN-UHFFFAOYSA-N
SMILES C1(N)=CC=C(OC2C3C(N=CC=2)=CC(OC)=C(OC)C=3)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2933.49.7000
NFPA 704
0
2 0

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D5070 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7 200mg $155 2024-03-01 Buy
TCI Chemical D5070 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7 1g $460 2024-03-01 Buy
Chem-Impex 43936 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline,≥98%(HPLC) ≥98%(HPLC) 190728-25-7 1G $540.8 2021-12-16 Buy
AK Scientific J90694 4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine 190728-25-7 1g $20 2021-12-16 Buy
Ambeed A138452 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline 97% 190728-25-7 5g $54 2021-12-16 Buy
Product number Packaging Price Buy
D5070 200mg $155 Buy
D5070 1g $460 Buy
43936 1G $540.8 Buy
J90694 1g $20 Buy
A138452 5g $54 Buy

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Chemical Properties,Uses,Production

Uses

4-(6,7-Dimethoxy-Quinolin-4-Yloxy)-Phenylamine is used in preparation of Cabozantinib Defluorination impurity.

Chemical Reactivity

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline is a primary alcohol that has been shown to catalyze the reaction of potassium carbonate with an alkali metal hydroxide to produce potassium. It has also been shown to be a base catalyst for the reaction of cyclopropanecarboxylic acid with an alcohol ester to produce high yield.

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline synthesis

35654-56-9
123-30-8
190728-25-7
Synthesis of 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline from 4-chloro-6,7-dimethoxyquinoline and 4-Aminophenol

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

Cabozantinib

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Suppliers

Global( 190)Suppliers
Supplier Tel Email Country ProdList Advantage
Huanfu Industrial Co.，（Shanghai）Ltd.
+86-18001856580 +86-18001856580 2415195517@qq.com China 43 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shandonghaohong biotechnology Co.,ltd. 		0635-6175299 13961496334 sale@inyelchem.com CHINA 44 55
Anqing Chico Pharmaceutical Co., Ltd. 		15380796838 chloewu@chicopharm.cn CHINA 341 58
Lianyungang happen teng technology co., LTD 		15950718863 wang666xt@163.com CHINA 295 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Supplier Advantage
Huanfu Industrial Co.，（Shanghai）Ltd.
58
Henan Fengda Chemical Co., Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Shandonghaohong biotechnology Co.,ltd. 		55
Anqing Chico Pharmaceutical Co., Ltd. 		58
Lianyungang happen teng technology co., LTD 		58
career henan chemical co 		58

View Lastest Price from 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline pictures 2024-01-02 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
190728-25-7
 US $200.00-1.00 / KG 1KG 99%, 99.5% Sublimated g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline pictures 2023-12-26 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
190728-25-7
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- pictures 2023-03-12 BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-
190728-25-7
 US $0.00 / kg 1kg 98.0%min 100kg LY Global chemicals co.,ltd .

190728-25-7(4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline)Related Search:

1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Cabozantinib Malate
BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- [4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]amine 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 6,7-Dimethoxy-4-(4-aminophenoxy)quinoline BenzeMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-BenzenaMine 4-(2,3-dimethoxynaphthalen-5-yloxy)benzenamine Intermediate 1 of Cabozantinib 4-(6,7-dimethoxy quinolinoxy) aniline 4-[(6,7-dimethoxy-4-quinolinyl)oxy]- 6,7-Dimethoxy-4-(4-aminophenyloxy)quinolone 4-[(6,7-dimethoxyquinolin-4-yl)oxy]aniline 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Cabozantinib Genotoxic Impurity I 4-(6,7-Dimethoxy-quinoL 4-(4-Aminophenoxy)-6,7-dimethoxyquinoline CAS 190728-25-7 BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- 4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline Cabozantinib Amine Analog Benzenam 1-((6,7-dimethoxyquinolin-4-yl)oxy)aniline 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline? (Cabozantinib Impurity) 190728-25-7 190827-25-7