ChemicalBook >> CAS DataBase List >>3-Pentanone


Chemical Name:
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Last updated:2023-08-24 18:22:36

3-Pentanone Properties

Melting point -42 °C (lit.)
Boiling point 101.5 °C (lit.)
Density 0.813 g/mL at 25 °C (lit.)
vapor density 3 (vs air)
vapor pressure 20 mm Hg ( 28 °C)
refractive index n20/D 1.392(lit.)
Flash point 55 °F
storage temp. Store below +30°C.
solubility water: slightly soluble
form Liquid
color Clear colorless
Relative polarity 0.265
PH 6.2 (50g/l, H2O, 20℃)
Odor at 0.10 % in propylene glycol. ethereal acetone
Odor Type ethereal
explosive limit 1.6-7.7%(V)
Water Solubility 50 g/L (20 ºC)
Merck 14,3121
BRN 635749
Exposure limits TLV-TWA 705 mg/m3 (200 ppm) (ACGIH).
Stability Stable. Highly flammable. Readily forms explosive mixtures with air. Incompatible with strong bases, reducing agents, strong oxidizing agents.
LogP 0.85 at 25℃
CAS DataBase Reference 96-22-0(CAS DataBase Reference)
NIST Chemistry Reference 3-Pentanone(96-22-0)
EPA Substance Registry System 3-Pentanone (96-22-0)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
Signal word  Danger
Hazard statements  H225-H319-H335-H336
Precautionary statements  P210-P233-P240-P241-P242-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-37-66-67
Safety Statements  9-16-25-33
RIDADR  UN 1156 3/PG 2
WGK Germany  1
RTECS  SA8050000
Autoignition Temperature 845 °F
HS Code  2914 19 90
HazardClass  3
PackingGroup  II
Toxicity LD50 orally in rats: 2.1 g/kg, Smyth et al., Arch. Ind. Hyg. Occup. Med. 10, 61 (1954)
NFPA 704
1 0

3-Pentanone price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.03605 Diethyl ketone for synthesis 96-22-0 1L $58.5 2023-06-20 Buy
Sigma-Aldrich 8.03605 Diethyl ketone for synthesis 96-22-0 100ML $60.1 2023-06-20 Buy
Sigma-Aldrich 127604 3-Pentanone ReagentPlus , ≥99.0% (GC) 96-22-0 4l $253 2023-06-20 Buy
Sigma-Aldrich 127604 3-Pentanone ReagentPlus?, ≥99.0% (GC) 96-22-0 18L $665 2023-06-20 Buy
TCI Chemical P0061 3-Pentanone >98.0%(GC) 96-22-0 25mL $22 2023-06-20 Buy
Product number Packaging Price Buy
8.03605 1L $58.5 Buy
8.03605 100ML $60.1 Buy
127604 4l $253 Buy
127604 18L $665 Buy
P0061 25mL $22 Buy

3-Pentanone Chemical Properties,Uses,Production

Chemical Properties

3-Pentanone (also known as diethyl ketone) is a member of the class of compounds known as ketones. It is a colorless liquid ketone with an odor like that of acetone. It is soluble in about 25 parts water, but miscible with organic solvents.3-pentanone is an acetone and ethereal tasting compound and can be found in a number of food items such as strawberry guava, ceylon cinnamon, beech nut, and pak choy, which makes 3-pentanone a potential biomarker for the consumption of these food products.


3-Pentanone may be used to evaluate excess molar volumes of its binary mixtures with 1-chloroalkanes at 298.15K and atmospheric pressure.


Diethyl ketone is used as a solvent, inmedicine, and in organic synthesis.


3-Pentanone is mainly used as a solvent in paint and a precursor to vitamin E. It is used as a reagent to synthesize ethyl 2-cyano-3,3-diethylacrylate by Knoevenagel condensation. It also shows anticonvulsant effect in several types of mouse seizure models. It serves as an intermediate in the manufacture of pharmaceuticals.


ChEBI: A pentanone that is pentane carrying an oxo group at position 3. It has been isolated from Triatoma brasiliensis and Triatoma infestans.

General Description

A clear colorless liquid with an acetone-like odor. Flash point 55°F. Less dense than water. Vapors heavier than air.

Air & Water Reactions

Highly flammable. Slightly soluble in water

Reactivity Profile

3-Pentanone is incompatible with the following: Strong oxidizers, alkalis, mineral acids, (hydrogen peroxide + nitric acid) .

Health Hazard

Diethyl ketone is a mild narcotic compoundas well as an irritant. Its acute toxicity is lessthan that of methyl propyl ketone. Exposureto 80,000 ppm for 4 hours was fatal to rats.
LD50 value, oral (rats): 2140 mg/kg.

Health Hazard

Liquid causes eye burn. Vapor irritates eyes, nose and throat; can cause headache, dizziness, nausea, weakness, and loss of consciousness.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Flammability and Explosibility

Highly flammable

Safety Profile

Moderately toxic by routes. A skin and eye irritant. Mutation data reported. Dangerous fre hazard when exposed to heat or flame; can react vigorously with oxidzing materials. To fight fire, use alcohol foam, foam, CO2, dry chemical. Reacts with hydrogen peroxide + nitric acid to form a shockand heat sensitive explosive peroxide. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.


Ketonic decarboxylation route
3-Pentanone is produced by ketonic decarboxylation of propanoic acid using metal oxide catalysts:
2 CH3CH2CO2H → (CH3CH2)2CO + CO2 + H2O
in the laboratory, the reaction can be conducted in a tube furnace.
Other way to make 3-pentanone: Acetone + very strong base and then + methylating agent -> butanone. Butanone + very strong base, then + methylating agent -> mixture of 3-methylbutanone and 3-pentanone.
Synthesis of 3-pentanone from 1-propanol over CeO2–Fe2O3 catalysts
Vogel's Textbook of Practical Organic Chemistry

Purification Methods

Dry it with anhydrous CaSO4 or CuSO4, and distil from P2O5 under N2 or under reduced pressure. Further purification is by conversion to the semicarbazone (recrystallise to constant m 139o, from EtOH) which, after drying in vacuo over CaCl2 and paraffin wax, is refluxed for 30minutes with excess oxalic acid, then steam distilled and salted out with K2CO3. Dry with Na2SO4 and distil [Cowan et al. J Chem Soc 171 1940]. [Beilstein 1 IV 3279.]

Waste Disposal

Incineration; molten salt treatment.

Global( 304)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
15028179902 +8615028179902 China 10950 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 China 21975 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 China 1807 55
+undefined-21-51877795 China 32047 60
Anhui Royal Chemical Co., Ltd.
+86-25-86655873 +8613962173137 China 535 55
Hubei Jusheng Technology Co.,Ltd.
18871490254 CHINA 28184 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 China 8868 58
Hubei xin bonus chemical co. LTD
86-13657291602 CHINA 22971 58
+8618523575427 China 47427 58
career henan chemical co
+86-0371-86658258 China 29829 58

View Lastest Price from 3-Pentanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Pentanone pictures 2023-08-24 3-Pentanone
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
3-Pentanone pictures 2023-07-27 3-Pentanone
US $1.10 / g 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
3-Pentanone pictures 2021-04-22 3-Pentanone
US $10.00 / PCS 1KG 99% 100 mt Hebei Guanlang Biotechnology Co., Ltd.
  • 3-Pentanone pictures
  • 3-Pentanone
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
  • 3-Pentanone pictures
  • 3-Pentanone
  • US $1.10 / g
  • 99.0% Min
  • Shaanxi Didu New Materials Co. Ltd
  • 3-Pentanone pictures
  • 3-Pentanone
  • US $10.00 / PCS
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
ZED2EK (C2H5)2CO 1,3-Dimethylacetone ethylpropionyl Metacetone Methacetone Pentan-3-on Pentanon-3 Pentanone-3 3-PENTANONE, 96%, HPLC GRADE 3-PENTANONE, REAGENTPLUS, >=99% 3-PENTANONE 99+% 3-PENTANON OEKANAL 3-PENTANONE, STANDARD FOR GC DiethylKetone,Certified 3-Pentanone,98% DIETHYL KETONE ( 3-PENTANONE ) pentanone,3-pentanone pentan-3-one diethyl ketone 3-Pentanone, 98%, pure 3-Pentanone, 98% 500ML 3-Pentanone, pure, 98% DIMETHYLACETONE 3-PENTANONE Diathylketon Diethylcetone diethylcetone(french) Diethylketon Diethyl Ketone Propione DIETHYL KETONE FOR SYNTHESIS 3-Pentanone, standard for GC,>99.5%(GC) Protein DEK ketone,3-Pentanone 3-Pentanone for HPLC, 96% 3-Pentanone ReagentPlus(R), >=99.0% (GC) 3-Oxopentane 3-Pentanone (DEK) 3-Pentanone, 99.5% 3-Pentanone> DIETHYL KETONE FOR SYNTHESIS 1 L DIETHYL KETONE FOR SYNTHESIS 100 ML Diethylketone, puriss, 99% Pentan-3-One, Technical, Fisher Chemical Diethyl Ketone (3-Pentanone) extrapure, 99% ETHYL KETONE DIETHYL KETONE PROPIONE PENTAN-3-ONE 3-Pentanon DEK Ethyl propionyl ANTI-DEK(C-TERMINAL) antibody produced in rabbit Oseltamivir Impurity 70 (3-Pentanone) 96-22-0 96220 C2H5COC2H5 CH3CH2COCH2CH3 Carbonyl Compounds