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Lineoyl LPA

CAS No.
65528-85-0
Chemical Name:
Lineoyl LPA
Synonyms
Lineoyl LPA;18:2 Lyso PA;D-(+)-Sn-1-o-linoleoyl-glyceryl-3-phosphate (linoleoyl lpa);9,12-Octadecadienoic acid (9Z,12Z)-, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester
CBNumber:
CB52709788
Molecular Formula:
C21H39O7P
Molecular Weight:
434.5
MDL Number:
MOL File:
65528-85-0.mol
Last updated:2025-01-27 09:38:02

Lineoyl LPA Properties

Boiling point 582.0±60.0 °C(Predicted)
Density 1.116±0.06 g/cm3(Predicted)
storage temp. -20°C
pka 1.82±0.10(Predicted)
form liquid
UNSPSC Code 51191904
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements  P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313

Lineoyl LPA Chemical Properties,Uses,Production

Uses

1-Linoleoyl-sn-glycero-3-phosphate is used in the administration of a therapeutically effective amount of ENPP2 inhibitor PF-8380 to individuals in which increased levels of LPA subtype suggest an increased risk of cardiovascular disease due to chronic viral infection.

Definition

ChEBI: 1-linoleoyl-sn-glycerol 3-phosphate is a 1-acyl-sn-glycerol 3-phosphate having linoleyl (9Z,12Z-octadecadienoyl) as the 1-O-acyl group. It is a conjugate acid of a 1-linoleoyl-sn-glycero-3-phosphate(2-).

Biological Activity

18:2 Lysophosphatidic acid (LPA) is an active ingredient of gintonin, which is a bioactive ligand of ginseng. LPA is synthesized in plants by the activity of the enzyme glycerol 3-phosphate acyltransferase (GPAT). LPA is an intermediate in the synthesis of phosphatidic acid (PA) and other phospholipids. Abnormal LPA metabolism is found in children with autism.

Lineoyl LPA Preparation Products And Raw materials

Raw materials

Preparation Products

Lineoyl LPA Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
J & K SCIENTIFIC LTD. 18210857532 jkinfo@jkchemical.com China 96815 76
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57422 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12064 58
Merck KGaA 21-20338288 ordercn@merckgroup.com China 6394 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 6051 58
Lineoyl LPA 18:2 Lyso PA 9,12-Octadecadienoic acid (9Z,12Z)-, (2R)-2-hydroxy-3-(phosphonooxy)propyl ester D-(+)-Sn-1-o-linoleoyl-glyceryl-3-phosphate (linoleoyl lpa) 65528-85-0