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RS-102895 hydrochloride

CAS No.
1173022-16-6
Chemical Name:
RS-102895 hydrochloride
Synonyms
3-trihydroxybenzene;RS-102895;RS 102895;RS102895;1'-(4-(Trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride;Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride (1:1)
CBNumber:
CB52729375
Molecular Formula:
C21H22ClF3N2O2
Molecular Weight:
426.86
MDL Number:
MFCD08703093
MOL File:
1173022-16-6.mol
Last updated:2023-09-20 16:43:00

RS-102895 hydrochloride Properties

storage temp. Inert atmosphere,Room Temperature
solubility DMF: 25 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml; Ethanol: 2 mg/ml
form Powder

RS-102895 hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18207 RS 102895 (hydrochloride) ≥98% 1173022-16-6 1mg $34 2024-03-01 Buy
Cayman Chemical 18207 RS 102895 (hydrochloride) ≥98% 1173022-16-6 5mg $85 2024-03-01 Buy
Cayman Chemical 18207 RS 102895 (hydrochloride) ≥98% 1173022-16-6 10mg $133 2024-03-01 Buy
Cayman Chemical 18207 RS 102895 (hydrochloride) ≥98% 1173022-16-6 25mg $288 2024-03-01 Buy
TRC R701005 RS 102895 hydrochloride 1173022-16-6 10mg $145 2021-12-16 Buy
Product number Packaging Price Buy
18207 1mg $34 Buy
18207 5mg $85 Buy
18207 10mg $133 Buy
18207 25mg $288 Buy
R701005 10mg $145 Buy

RS-102895 hydrochloride Chemical Properties,Uses,Production

Description

The chemokine CCL2, also known as monocyte chemotactic protein-1 (MCP-1), stimulates leukocyte chemotaxis to sites of inflammation via signaling through the MCP-1 receptor, CCR2. RS 102895 is a spiropiperidine compound that acts as a CCR2 antagonist (IC50 = 0.36 μM). It inhibits the related CCR1 receptor with an IC50 value of 17.8 μM and inhibits adrenergic α1a, α1d, and 5HT1A receptors with IC50 values of 0.13, 0.32, and 47 μM, respectively. RS 102895 prevents chemotaxis of THP-1 cells (IC50 = 1.7 μM) when MCP-1 is presented as a chemoattractant.

Uses

RS 102895 Hydrochloride is used as a leukocyte infiltrate marker for rosacea diagnosis.

storage

Desiccate at RT

RS-102895 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Biochempartner
0086-13720134139 candy@biochempartner.com CHINA 967 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9425 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58

View Lastest Price from RS-102895 hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RS-102895 hydrochloride pictures 2022-09-08 RS-102895 hydrochloride
1173022-16-6
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
RS-102895 hydrochloride pictures 2020-02-19 RS-102895 hydrochloride
1173022-16-6
US $1.00 / KG 1KG 99% 200kgs Career Henan Chemical Co
Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride 3-trihydroxybenzene Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-, hydrochloride (1:1) RS-102895;RS 102895;RS102895 1'-(4-(Trifluoromethyl)phenethyl)spiro[benzo[d][1,3]oxazine-4,4'-piperidin]-2(1H)-one hydrochloride 1173022-16-6