Pyrazofurin
- CAS No.
- 30868-30-5
- Chemical Name:
- Pyrazofurin
- Synonyms
- PRZF;47599;A-23813;nsc143095;pyrazofurin;pirazofurin;Pyrazomycin;Pyrozofurin;compound47599;β-Pyrazofurin
- CBNumber:
- CB5276253
- Molecular Formula:
- C9H13N3O6
- Molecular Weight:
- 259.22
- MDL Number:
- MFCD07995040
- MOL File:
- 30868-30-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Pyrazofurin ≥98% (HPLC) | SML1502 | 5mg | $154 |
| Pyrazofurin ≥98% (HPLC) | SML1502 | 25mg | $585.2 |
| PYRAZOFURIN 95.00% | API0008977 | 10MG | $666.75 |
| PYRAZOFURIN 95.00% | API0008977 | 100MG | $3433.5 |
| Pyrazofurin ≥98.0% | CS-0085864 | 5mg | $400 |
| Boiling point | 584.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.785±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO, Water (Slightly) |
| pka | 7.17±0.50(Predicted) |
| form | powder |
| color | white to light brown |
| optical activity | [α]/D -49 to -39°, c = 0.5 in H2O |
| Water Solubility | H2O: 5mg/mL, clear (warmed) |
| Stability | Hygroscopic |
| EWG's Food Scores | 1 |
| FDA UNII | 4B15044GQZ |
| NCI Drug Dictionary | pyrazofurin |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
Pyrazofurin price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1502 | Pyrazofurin ≥98% (HPLC) | 30868-30-5 | 5mg | $154 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML1502 | Pyrazofurin ≥98% (HPLC) | 30868-30-5 | 25mg | $585.2 | 2025-07-31 | Buy |
| American Custom Chemicals Corporation | API0008977 | PYRAZOFURIN 95.00% | 30868-30-5 | 10MG | $666.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008977 | PYRAZOFURIN 95.00% | 30868-30-5 | 100MG | $3433.5 | 2021-12-16 | Buy |
| ChemScene | CS-0085864 | Pyrazofurin ≥98.0% | 30868-30-5 | 5mg | $400 | 2021-12-16 | Buy |
Pyrazofurin Chemical Properties,Uses,Production
Uses
Geldanamycin (G304500) derivative.
Definition
ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.
Biochem/physiol Actions
Pyrazofurin serves as an effective drug against HIV (human immuno virus), vaccinia virus, West Nile viral infection.
Enzyme inhibitor
This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.
in vivo
Pyrazofurin (0.25-5 mg/kg; subcutaneous injection; 5 days) has an ameliorative effect in mice infected with Rift Valley fever virus[4].
| Animal Model: | Rift Valley fever virus-infected female Swiss Webster mice aged 3-4 weeks old[4] |
| Dosage: | 0.25, 2.5 and 10 mg/kg |
| Administration: | Subcutaneous injection (s.c.); 5 days |
| Result: | Increased survival rate and generally prolonged life at 0.25 mg/kg dose. Was uniformly ineffective at protecting mice from death but did increase the time to death at 2.5 mg/kg dose. Had toxic to mice at high doses (10 mg/kg). |
Pyrazofurin Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrazofurin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3999 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20405 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39042 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532; 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32321 | 50 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 | shenlinxing@macklin.cn | China | 15872 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9171 | 60 |
| Supplier | Advantage |
|---|---|
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| BOC Sciences | 58 |
| TargetMol Chemicals Inc. | 58 |
| Alfa Chemistry | 58 |
| TargetMol Chemicals Inc. | 58 |
| J & K SCIENTIFIC LTD. | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 50 |
| Shanghai Macklin Biochemical Co.,Ltd. | 55 |
| Sigma-Aldrich | 80 |
| Alfa Chemistry | 60 |
View Lastest Price from Pyrazofurin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-19 | Pyrazofurin
30868-30-5
|
US $1930.00-1270.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-07-22 | Pyrazofurin
30868-30-5
|
US $1.00 / Kg | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-
- Pyrazofurin
30868-30-5
- US $1930.00-1270.00 / mg
- TargetMol Chemicals Inc.
-
- Pyrazofurin
30868-30-5
- US $1.00 / Kg
- 98%
- Shaanxi Dideu Medichem Co. Ltd
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