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Raffinose

CAS No.
512-69-6
Chemical Name:
Raffinose
Synonyms
D-RAFFINOSE;melitriose;Cottonseed oligosaccharides;ffinose;NSC 2025;NSC26414;RAFFINOSE;gossypose;NSC-26414;NSC 26414
CBNumber:
CB5290712
Molecular Formula:
C18H32O16
Molecular Weight:
504.44
MDL Number:
MFCD00006630
MOL File:
512-69-6.mol
MSDS File:
SDS
Last updated:2023-11-02 11:53:15

Raffinose Properties

Melting point 81℃
Boiling point 513.84°C (rough estimate)
Density 1.81
refractive index 1.6760 (estimate)
storage temp. 2-8°C
solubility |DMSO : 100 mg/mL (198.24 mM; Need ultrasonic)
form Solid
pka pK1:12.74 (25°C)
color White to Off-White
Water Solubility 229.8g/L(25 ºC)
Stability Stable. Incompatible with strong oxidizing agents. Combustible.
LogP -5.104 (est)
CAS DataBase Reference 512-69-6(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII N5O3QU595M
EPA Substance Registry System .alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl O-.alpha.-D-galactopyranosyl-(1.fwdarw.6)- (512-69-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P501-P270-P264-P301+P312+P330
Safety Statements  24/25
HS Code  29389090

Raffinose price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC R730105 D-(+)-Raffinose 512-69-6 5g $75 2021-12-16 Buy
Matrix Scientific 097922 D-Raffinose 95+% 512-69-6 10g $255 2021-12-16 Buy
American Custom Chemicals Corporation CRB0003054 RAFFINOSE 95.00% 512-69-6 5MG $499.32 2021-12-16 Buy
Biorbyt Ltd orb105219 Raffinose >98%,Standard References Grade 512-69-6 20mg $569.5 2021-12-16 Buy
AK Scientific J99531 D-(+)-Raffinose 512-69-6 5g $70 2021-12-16 Buy
Product number Packaging Price Buy
R730105 5g $75 Buy
097922 10g $255 Buy
CRB0003054 5MG $499.32 Buy
orb105219 20mg $569.5 Buy
J99531 5g $70 Buy

Raffinose Chemical Properties,Uses,Production

Description

Raffinose is also called melitose, melitriose, or gossypose.The term raffinose is derived from the French word raffiner (to refine),owing to the fact that it was identified first in the products of beet-sugar refining.Raffinose is found in sugar-beets in small quantities and also in cotton seeds.Raffinose is a trisaccharide composed of galactose, fructose, and glucose. It can be found in beans, cabbage, brussels sprouts, broccoli, asparagus, and other plants. In plants, raffinose is generated via binding of galactinol (a sugar alcohol) to sucrose. Raffinose has only 20 % of the sweetening intensity of sucrose.It is much more readily soluble in hot water than sucrose,consequently it remains in syrups and molasses during sugar refining process,especially in those products obtained from the process of extracting sugarfrom molasses.

Chemical Properties

Raffinose is a white crystalline powder. It is odorless and has a sweet taste approximately 10% that of sucrose.

Uses

D-(+)-Raffinose is an oligosaccharide and trisaccharide whose physical structure and chemical properties have been shown to affect the stability and crystallization of amorphous sucrose, helping to increase the shelf-life of sucrose-containing foods.

Definition

ChEBI: Raffinose is a trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively. It has a role as a plant metabolite, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a raffinose family oligosaccharide and a trisaccharide.

Production Methods

Raffinose occurs naturally in Australian manna, cottonseed meal, and seeds of various food legumes. It can be isolated from beet sugar molasses through sucrose separation, seed-crystallization, and filtration.

Pharmaceutical Applications

Raffinose is a trisaccharide carbohydrate that is used as a bulking agent, blood substitute, stabilizing agent, and water scavenger in freeze-drying where it acts as a stabilizer for freeze-dried formulations. It is also used as a crystallization inhibitor in sucrose solutions.

Safety

Raffinose is a naturally occurring trisaccharide investigated for use in freeze-dried pharmaceutical formulations. It occurs in a number of plants that are consumed widely.

storage

Raffinose is stable under ordinary conditions of use and storage. Excessive heat should be avoided to prevent degradation. Thermal decomposition products are carbon monoxide and carbon dioxide.

Purification Methods

fructo-furanose [17629-30-0 (5H2O), 512-69-6 (anhydrous)] M 594.5, m 8 0o, 80 -82o, +124o (c 10, H2O), [ ] D +105o (c 1 for pentahydrate, H2O), pK 1 12.40, pK 2 13.44, pK 3 13.52. D(+)-Raffinose crystallises from H2O, 90% aqueous EtOH or MeOH as the pentahydrate. The anhydrous sugar has m 132-135o. It has RF 0.8 on TLC (Silica Gel, and 1:3:3 CHCl3/butanone:/MeOH). The undecaacetate has been purified through an alumina column by elution with CHCl3, and recrystallised from EtOH/MeOH/H2O (3:2:5), with m 99-100o, [] D +92.8o (c 5.14, EtOH). [pK : Coccioli & Vicedomini Ann Chim (Rome) 66 269, 275 1976, 1H NMR: Suami et al. Carbohydr Research 26 234 1973, Beilstein 17 III/IV 3801, 17/8 V 403.]

Incompatibilities

Raffinose is incompatible with strong oxidizers.

Regulatory Status

Raffinose is a naturally occurring trisaccharide and is consumed as part of a normal diet.

57-50-1
7493-95-0
512-69-6
Synthesis of Raffinose from Sucrose and 4-NITROPHENYL-ALPHA-D-GALACTOPYRANOSIDE

Raffinose Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 230)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Hebei Yanxi Chemical Co., Ltd.
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Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
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028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58

View Lastest Price from Raffinose manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Raffinose pictures 2023-11-02 Raffinose
512-69-6
US $20.00-10.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
Raffinose pictures 2023-10-17 Raffinose
512-69-6
US $0.00-0.00 / kg 1kg 99% 50000kg Hebei Yibangte Import and Export Co. , Ltd.
Raffinose pictures 2023-09-06 Raffinose
512-69-6
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
  • Raffinose pictures
  • Raffinose
    512-69-6
  • US $20.00-10.00 / kg
  • 0.99
  • Hebei Yanxi Chemical Co., Ltd.
  • Raffinose pictures
  • Raffinose
    512-69-6
  • US $0.00-0.00 / kg
  • 99%
  • Hebei Yibangte Import and Export Co. , Ltd.
  • Raffinose pictures
  • Raffinose
    512-69-6
  • US $0.00-0.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co., Ltd.
.beta.-D-fructofuranosylO-.alpha.-D-galactopyranosyl-(1→6)-.alpha.-D-Glucopyranoside .fwdarw.)- alpha-d-glucopyranoside,beta-d-fructofuranosylo-alpha-d-galactopyranosyl-(1-6 gossypose raffinose,pure RAFFINOSE RAFFINOSE, D-(+) D-(+)-RAFFINOSE ALPHA-D-GALACTOPYRANOSYL-(1->6)-ALPHA-D-GLUCOPYRANOSYL-(1->2)-BETA-D-FRUCTOFURANOSIDE ALPHA-D-RAFFINOSE (3R,4S,5S,6R)-2-[[(2R,3R,4S,5R)-6-[(2S,3S,4R,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxy-oxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol raffinose, pure Raffinose β-D-Fructofuranosyl 6-O-α-D-galactopyranosyl-α-D-glucopyranoside RADDEANIN A (RG) Nittenraffinose NSC 170228 NSC 2025 ffinose Raffinose D-Raffinose .alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl O-.alpha.-D-galactopyranosyl-(1.fwdarw.6)- RaffinoseSolution,5mg/L,1ml Raffinose(b) α-D-Glucopyranoside, β-D-fructofuranosyl O-α-D-galactopyranosyl-(1→6)- Raffino-oligosaccharide NSC-26414 NSC26414 NSC 26414 melitriose D-RAFFINOSE Cottonseed oligosaccharides Lumateperone Impurity 17 512-69-6