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Benidipine hydrochloride

Benidipine hydrochloride
Benidipine hydrochloride structure
CAS No.
91599-74-5
Chemical Name:
Benidipine hydrochloride
Synonyms
Conipros;Benidipine hydrochlo;Benidipine Impurity 4;Benidipine hydrochloride;rac Benidipine Hydrochloride;(4R)-rel-3,5-Pyridinedicarboxylic acid;Coniel, Capadipine, KW-3049, Nacadipine;3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester;monohydrochloride,(r*,r*)-(+-)-hyl1-(phenylmethyl)-3-piperidinyleste;2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-DimethoxyCarboxylate
CBNumber:
CB5294563
Molecular Formula:
C28H31N3O6
Formula Weight:
505.56
MOL File:
91599-74-5.mol

Benidipine hydrochloride Properties

Melting point:
199-201°C
storage temp. 
Desiccate at RT
solubility 
DMSO: ≥20mg/mL
pka
7.34(at 25℃)
form 
powder
color 
yellow
InChIKey
DGVVISBYHUXFIU-UHFFFAOYSA-N
CAS DataBase Reference
91599-74-5(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
RTECS  US7975657
Toxicity LD50 orally in male mice: 218 mg/kg (Muto, 1988)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Benidipine hydrochloride price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B6813 Benidipine hydrochloride ≥98% (HPLC) 91599-74-5 10mg $71.1 2018-11-20 Buy
Sigma-Aldrich B6813 Benidipine hydrochloride ≥98% (HPLC) 91599-74-5 50mg $274 2018-11-20 Buy
Cayman Chemical 21607 Benidipine (hydrochloride) ≥98% 91599-74-5 10mg $29 2018-11-19 Buy
Cayman Chemical 21607 Benidipine (hydrochloride) ≥98% 91599-74-5 25mg $47 2018-11-19 Buy
Cayman Chemical 21607 Benidipine (hydrochloride) ≥98% 91599-74-5 50mg $65 2018-11-19 Buy

Benidipine hydrochloride Chemical Properties,Uses,Production

Description

Benidipine hydrochloride is a new, long acting dihydropyridine calcium antagonist useful in the treatment of hypertension and angina pectoris. In experimental animals, benidipine hydrochloride dose dependently induced hypotension with a potency of 6 and 12 times more than nifedipine and nicardipine, respectively. It also exhibited a slow onset of action.

Chemical Properties

Yellow Crystalline Powder

Originator

Kyowa Hakko (Japan)

Uses

A dihydropyridine calcium channel blocker. Antihypertensive.

brand name

Coniel

Biological Activity

Orally active antihypertensive agent which displays a wide range of activities in vitro and in vivo . Inhibits L-, N- and T-type Ca 2+ channels. Also inhibits aldosterone-induced mineralocorticoid receptor activation. Exhibits cardioprotective and antiartherosclerotic effects.

Benidipine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Benidipine hydrochloride Suppliers

Global( 119)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Hubei XinRunde Chemical Co., Ltd.
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02783214688 bruce@xrdchem.cn CHINA 552 55
Shanghaizehan biopharma technology co., Ltd. 0086-021-61350663 13052117465
0086-021-61350662 sales@zehanbiopharma.com China 811 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
Chembest Research Laboratories Limited +86(0)21-20908456
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Chemsky(shanghai)International Co.,Ltd. 021-50135380
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China Langchem Inc. 0086-21-58956006,021-38701807;021-58950017
0086-21-58956100 sales@langchem.com China 7884 57
Jinan Haohua Industry Co., Ltd 0531-58773082 ;58773060
0531-58773099 sales@jnhaohua.com China 5621 58
Wuhan Fortuna Chemical Co., Ltd +86-27-59207852 85767163
+86-27-59524646 info@fortunachem.com China 3086 58

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