2-(Aminomethyl)-1-ethylpyrrolidine
- CAS No.
- 26116-12-1
- Chemical Name:
- 2-(Aminomethyl)-1-ethylpyrrolidine
- Synonyms
- Sulpiride impurity A CRS;Amisulpride EP Impurity A;1-ethylpyrrolidin-2-ylmethylamine;)-1-ethyL;Refer to S-402;Sulpiride EP Impurity A;Sulpiride Impurity A(EP);1-Ethyl-2-pyrrolidinemethylamine;n-ethyl-2-methylaminopyrrolidine;N-ETHYL-2-AMINOMETHYLPYRROLIDINE
- CBNumber:
- CB5307995
- Molecular Formula:
- C7H16N2
- Molecular Weight:
- 128.22
- MDL Number:
- MFCD00003178
- MOL File:
- 26116-12-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-(Aminomethyl)-1-ethylpyrrolidine 97% | 655600 | 5g | $110 |
| Sulpiride impurity A European Pharmacopoeia (EP) Reference Standard | S2191000 | 20 mg | $241 |
| 2-(Aminomethyl)-1-ethylpyrrolidine 97% | 655600 | 25g | $519 |
| 2-(Aminomethyl)-1-ethylpyrrolidine >98.0%(GC)(T) | A2556 | 5g | $39 |
| 2-(Aminomethyl)-1-ethylpyrrolidine >98.0%(GC)(T) | A2556 | 25g | $113 |
| More product size | |||
| Boiling point | 58-60 °C16 mm Hg(lit.) |
|---|---|
| Density | 0.884 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 135 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), Methanol (Sparingly) |
| pka | 10.04±0.40(Predicted) |
| form | Liquid |
| color | Clear yellow |
| InChI | InChI=1S/C7H16N2/c1-2-9-5-3-4-7(9)6-8/h7H,2-6,8H2,1H3 |
| InChIKey | UNRBEYYLYRXYCG-UHFFFAOYSA-N |
| SMILES | N1(CC)CCCC1CN |
| LogP | 0.433 (est) |
| CAS DataBase Reference | 26116-12-1(CAS DataBase Reference) |
| FDA UNII | K2U95PPN4Z |
| NIST Chemistry Reference | 2-Pyrrolidinemethanamine, 1-ethyl-(26116-12-1) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS02,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226-H315-H319-H335 |
| Precautionary statements | P210-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 26-36 |
| RIDADR | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| HazardClass | 3.2 |
| PackingGroup | III |
| HS Code | 29339900 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
2-(Aminomethyl)-1-ethylpyrrolidine price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 655600 | 2-(Aminomethyl)-1-ethylpyrrolidine 97% | 26116-12-1 | 5g | $110 | 2026-04-30 | Buy |
| Sigma-Aldrich | S2191000 | Sulpiride impurity A European Pharmacopoeia (EP) Reference Standard | 26116-12-1 | 20 mg | $241 | 2026-04-30 | Buy |
| Sigma-Aldrich | 655600 | 2-(Aminomethyl)-1-ethylpyrrolidine 97% | 26116-12-1 | 25g | $519 | 2026-04-30 | Buy |
| TCI Chemical | A2556 | 2-(Aminomethyl)-1-ethylpyrrolidine >98.0%(GC)(T) | 26116-12-1 | 5g | $39 | 2026-04-30 | Buy |
| TCI Chemical | A2556 | 2-(Aminomethyl)-1-ethylpyrrolidine >98.0%(GC)(T) | 26116-12-1 | 25g | $113 | 2026-04-30 | Buy |
2-(Aminomethyl)-1-ethylpyrrolidine Chemical Properties,Uses,Production
Chemical Properties
clear yellow liquid
Uses
2-(Aminomethyl)-1-ethylpyrrolidine is used as a reagent in the synthesis of S-Desethyl S-Methyl Amisulpride (D289595)
Synthesis
2167-14-8
26116-12-1
General procedure for the synthesis of N-ethyl-2-aminomethylpyrrolidine from 1-ethyl-1H-pyrrole-2-carboxaldehyde: 60 g of 1-ethyl-1H-pyrrole-2-carboxaldehyde was added to an autoclave, and 5 g of palladium-carbon catalyst at a mass percent concentration of 5% and 15 g of liquid ammonia were added to carry out hydrogenation and reductive amination reactions. The reaction conditions were hydrogen pressure of 35 kg and temperature of 95°C. After completion of the reaction, the system was cooled, the gas was expelled, and filtration was carried out. The filter cake was washed with methanol, and the filtrate and washings were combined to recover methanol. Finally, the target product N-ethyl-2-aminomethylpyrrole was obtained by purification via decompression distillation in a yield of 53.7 g and 86%. The reaction equation was as follows:
References
[1] Patent: CN107973735, 2018, A. Location in patent: Paragraph 0017; 0027-0029
2-(Aminomethyl)-1-ethylpyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29819 | 58 |
| NINGBO INNO PHARMCHEM CO., LTD. | 13867897135 | sales@nbinno.com | CHINA | 923 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2994 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
View Lastest Price from 2-(Aminomethyl)-1-ethylpyrrolidine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-02-02 | 2-(Aminomethyl)-1-ethylpyrrolidine
26116-12-1
|
US $1.00-1.00 / KG | 160KG | 99.0%GC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | |
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2025-12-01 | 2-(Aminomethyl)-1-ethylpyrrolidine
26116-12-1
|
US $0.00 / kg | 1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
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2025-05-26 | 2- (Aminomethyl) -1-Ethylpyrrolidine
26116-12-1
|
US $10.00 / KG | 1KG | 98% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD |
-

- 2-(Aminomethyl)-1-ethylpyrrolidine
26116-12-1
- US $1.00-1.00 / KG
- 99.0%GC
- Shaanxi Dideu Medichem Co. Ltd
-

- 2-(Aminomethyl)-1-ethylpyrrolidine
26116-12-1
- US $0.00 / kg
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-

- 2- (Aminomethyl) -1-Ethylpyrrolidine
26116-12-1
- US $10.00 / KG
- 98%
- Hebei Chuanghai Biotechnology Co,.LTD
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