ChemicalBook >> CAS DataBase List >>9-(BETA-D-ARABINOFURANOSYL)GUANINE
9-(BETA-D-ARABINOFURANOSYL)GUANINE
- CAS No.
- 38819-10-2
- Chemical Name:
- 9-(BETA-D-ARABINOFURANOSYL)GUANINE
- Synonyms
- Ara-G;Ara-Gr;Ara-rG;9-βNsc 76352;Ara G,AraG;Araguanosine;ara-Guanosine;Ara-G hydrate;arabinoguansine
- CBNumber:
- CB5316537
- Molecular Formula:
- C10H13N5O5
- Molecular Weight:
- 283.24
- MDL Number:
- MFCD00065486
- MOL File:
- 38819-10-2.mol
Last updated:2023-05-18 11:31:16
| Melting point | 225°C(lit.) |
|---|---|
| Density | 2.25±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO: >10mg/mL |
| pka | 9?+-.0.20(Predicted) |
| form | solid |
| color | White to Off-White |
| λmax | 252nm(lit.) |
| InChIKey | NYHBQMYGNKIUIF-FJFJXFQQSA-N |
| EWG's Food Scores | 1 |
| FDA UNII | 0Z99WX0GPF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| RTECS | MF8301000 |
| HS Code | 29349990 |
9-(BETA-D-ARABINOFURANOSYL)GUANINE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A4233 | Ara-G hydrate ≥98% (HPLC), solid | 38819-10-2 | 5mg | $146 | 2024-03-01 | Buy |
| Sigma-Aldrich | A4233 | Ara-G hydrate ≥98% (HPLC), solid | 38819-10-2 | 25mg | $557 | 2024-03-01 | Buy |
| TCI Chemical | A2739 | 9-beta-D-Arabinofuranosylguanine Hydrate >98.0%(HPLC) | 38819-10-2 | 10mg | $55 | 2024-03-01 | Buy |
| TCI Chemical | A2739 | 9-beta-D-Arabinofuranosylguanine Hydrate >98.0%(HPLC) | 38819-10-2 | 50mg | $193 | 2024-03-01 | Buy |
| Cayman Chemical | 27984 | Ara-G | 38819-10-2 | 100mg | $61 | 2024-03-01 | Buy |
9-(BETA-D-ARABINOFURANOSYL)GUANINE Chemical Properties,Uses,Production
Description
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine . Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporated into the DNA. Ara-G inhibits DNA replication by 92% after 30 minutes when used at a concentration of 50 μM in CEM cells, which are used as a model for human T lymphoblasts. It also halts the cell cycle at the sub-G1 phase and induces apoptosis in CEM cells. Syngeneic bone marrow containing 6C3HED tumor cells treated with ara-G (100 mM) ex vivo prior to transplantation increases survival of lethally irradiated mice and induces reconstitution of lymphoid, myeloid, and erythroid cell linages.
Uses
Ara-G is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic.
Definition
ChEBI: A purine nucleoside in which guanine is attached to arabinofuranose via a beta-N9-glycosidic bond. It inhibits DNA synthesis and causes cell death.
9-(BETA-D-ARABINOFURANOSYL)GUANINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 173)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Yunbio Tech Co.,Ltd. | +86-010-60605551 +86-18046518538 | yunbiochem@126.com | China | 321 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| Xi'an Yutbon Pharmaceutical Technology Co., Ltd | 029-81140587 +8618717328141 | sales@yutbon.com | China | 437 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from 9-(BETA-D-ARABINOFURANOSYL)GUANINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-10-14 | 9-beta-D-Arabinofuranosylguanine Hydrate
38819-10-2
|
US $0.00-0.00 / g | 1g | 98.0% | 1kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2021-07-13 | Arabinoguanosine
38819-10-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-10 | Arabinoguanosine
38819-10-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 9-beta-D-Arabinofuranosylguanine Hydrate
38819-10-2
- US $0.00-0.00 / g
- 98.0%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Arabinoguanosine
38819-10-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Arabinoguanosine
38819-10-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
38819-10-2(9-(BETA-D-ARABINOFURANOSYL)GUANINE)Related Search:
9-beta-D-Arabinofuranosylguanine Hydrate
2-AMino-9-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
Arabinoguanosine
Araguanosine
ara-Guanosine
Guanine arabinoside
9-β-D-Arabinofuranosyl guanine hydrate
9-&beta
2-amino-9-beta-d-arabinofuranosyl-1,9-dihydro-6h-purin-6-on
9-(beta-d-arabinofuranosyl)-guanin
9-(BETA-D-ARABINOFURANOSYL)GUANINE
GUANINE-9-ARABINOSIDE
ARABINOFURANOSYL-GUANINE
9-(b-D-Arabinofuranosyl)guanine
9-arabinofuranosylguanine
ARA-G 9-(BETA-D-ARABINOFURANOSYL)-GUANINE
2-Amino-9-β-D-arabinofuranosyl-1,9-dihydro-6H-purin-6-one
2-Amino-9-β-D-arabinofuranosyl-9H-purine-6(1H)-one
9-β-D-Arabinofuranosyl-1,6-dihydro-2-amino-6-oxo-9H-purine
9-β-D-Arabinofuranosyl-2-amino-9H-purin-6-ol
Arabinosylguanine
Ara-G
Ara-G hydrate
9-(β-D-Arabinoribofuranosyl)-guanine
6H-Purin-6-one, 2-amino-9-beta-D-arabinofuranosyl-1,9-dihydro-
Guanine, 9-(beta-D-arabinofuranosyl)-
Nsc 76352
9-(β-D-Arabinofuranosyl)guanine ,97%
-D-Arabinofuranosylguanine Hydrate
9-beta-Arabinosylguanine
6H-Purin-6-one,2-amino-9-b-D-arabinofuranosyl-1,9-dihydro-
2-amino-9-(beta-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one
Ara-G hydrate, 98%, inhibitor of DNA synthesis, an antimetabolite and antineoplastic.
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)-9,11-Epoxy-6-fluoropregna-1,4,16-triene-3,20-dione
1-β-D-Arabinofuranosylguanine
Ara-Gr
9-β-D-Arabinofuranosylguanine Hydrate >
6H-Purin-6-one, 2-amino-9-β-D-arabinofuranosyl-1,9-dihydro-
9-β-D-Arabinofuranosylguanine
Arabinofuranosyl-guanine (ara-G)
9-(BETA-D-ARABINOFURANOSYL)GUANINE USP/EP/BP
9-β-D-Arabinofuranosylguanine Hydrate
2-amino-9-(beta-D-arabinofuranosyl)-3,9-dihydro-6H-purin-6-o...
Ara G,AraG
6H-Purin-6-one, 2-amino-9-β-D-arabinofuranosyl-1,9-dihydro-