ChemicalBook >> CAS DataBase List >>AUNP-12
AUNP-12
- CAS No.
- 1353563-85-5
- Chemical Name:
- AUNP-12
- Synonyms
- AUR 012;AUNP-12;NP-12 TFA;Aurigene-012;Aurigene NP-12;AURIGENE-012;AUR 012;L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-
- CBNumber:
- CB53168755
- Molecular Formula:
- C142H226N40O48
- Molecular Weight:
- 3261.55
- MDL Number:
- MFCD01779848
- MOL File:
- 1353563-85-5.mol
Last updated:2023-06-08 09:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H400-H410 | |||||||||
| Precautionary statements | P264-P270-P273-P301+P312-P330-P391-P501 | |||||||||
| NFPA 704 |
|
AUNP-12 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28053 | AUNP-12 | 1353563-85-5 | 1mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 28053 | AUNP-12 | 1353563-85-5 | 5mg | $420 | 2024-03-01 | Buy |
| Biorbyt Ltd | orb611287 | AUNP-12 >98% | 1353563-85-5 | 100mg | $1949.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611287 | AUNP-12 >98% | 1353563-85-5 | 250mg | $3282.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611287 | AUNP-12 >98% | 1353563-85-5 | 1g | $5803.8 | 2021-12-16 | Buy |
AUNP-12 Chemical Properties,Uses,Production
Biological Activity
AUNP-12 (Aur-012, Aurigene-012, Aurigene NP-12), a novel immune checkpoint modulator, is an inhibitor of PD-1 signaling pathway.
in vitro
In hPDL2-expressing HEK293 cells, AUNP-12 inhibited the binding of PD1 to PDL2 with EC50 of 0.72 nM; in hPDL1-expressing MDA-MB231 cells, in PBMC proliferation assay, EC50 was 0.41 nM.
target
| Target | Value |
| PD-L1 (Cell-free assay) |
AUNP-12 Preparation Products And Raw materials
Raw materials
Preparation Products
AUNP-12 Suppliers
Global( 38)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Nanjing Leon Biological Technology Co., Ltd. | 17705183659 | sales@njleonbiotech.com | China | 5503 | 55 |
1353563-85-5(AUNP-12)Related Search:
AUNP-12
AUR 012
Aurigene-012
AURIGENE-012;AUR 012
L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-
Aurigene NP-12
NP-12 TFA
1353563-85-5
C142H226N40O48