Isoconazole nitrate
- CAS No.
- 24168-96-5
- Chemical Name:
- Isoconazole nitrate
- Synonyms
- Fazol;R 15454;Travogyn;Travogen;Adestan G 100;Gyno-Travogen;Gyno-travozen;ISOCONAZOLE NITRATE;IsoconazoleNitrate>Isosorbide itraconazole
- CBNumber:
- CB5317271
- Molecular Formula:
- C18H15Cl4N3O4
- Molecular Weight:
- 479.14
- MDL Number:
- MFCD01721647
- MOL File:
- 24168-96-5.mol
| Melting point | 178-182°C |
|---|---|
| storage temp. | Sealed in dry,2-8°C |
| solubility | Very slightly soluble in water, soluble in methanol, slightly soluble in ethanol (96 per cent). |
| color | White to Off-White |
| Merck | 14,5160 |
| CAS DataBase Reference | 24168-96-5(CAS DataBase Reference) |
| FDA UNII | 5AS8P3N30X |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H410 | |||||||||
| Precautionary statements | P273-P391-P501 | |||||||||
| RTECS | NI4772000 | |||||||||
| HS Code | 2933.29.4300 | |||||||||
| NFPA 704 |
|
Isoconazole nitrate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2232 | Econazole Impurity D Pharmaceutical Secondary Standard; Certified Reference Material | 24168-96-5 | 500MG | $143 | 2024-03-01 | Buy |
| Sigma-Aldrich | I0380000 | Isoconazole nitrate European Pharmacopoeia (EP) Reference Standard | 24168-96-5 | i0380000 | $153 | 2024-03-01 | Buy |
| TCI Chemical | I0834 | Isoconazole Nitrate >98.0%(HPLC)(T) | 24168-96-5 | 5g | $88 | 2024-03-01 | Buy |
| TCI Chemical | I0834 | Isoconazole Nitrate >98.0%(HPLC)(T) | 24168-96-5 | 25g | $222 | 2022-04-27 | Buy |
| Cayman Chemical | 30100 | Isoconazole (nitrate) | 24168-96-5 | 1g | $44 | 2024-03-01 | Buy |
Isoconazole nitrate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Originator
Fazol,Fournier,France,1979
Uses
Antibacterial; antifungal
Uses
Isoconazole Nitrate acts as an antibacterial in the local treatment of vaginitis; antifungal agent (1,2).
Manufacturing Process
To a stirred and refluxing solution of 40 parts of benzene and 35 parts of dimethylformamide (both solvents previously dried azeotropically) are added successively 1.6 parts of sodium hydride and 7.7 parts of α-(2,4- dichlorophenyl)imidazole-1-ethanol, (cooling on ice is necessary). After the addition is complete, stirring and refluxing is continued for 30 minutes. Then there are added 7.8 parts of 2.6-dichlorobenzyl chloride and the whole is stirred at reflux for another 3 hours. The reaction mixture is poured onto water and the product 1-[2,4-dichloro-b-(2,6-dichlorobenzyloxy)phenethyl] imidazole, is extracted with benzene. The extract is washed twice with water, dried, filtered and evaporated in vacuo. The base residue is dissolved in a mixture of acetone and diisopropyl ether and to this solution is added an excess of concentrated nitric acid solution. The precipitated nitrate salt is filtered off and recrystallized from a mixture of methanol and diisopropyl ether, yielding 1-[2,4-dichloro-b-(2,6-dichlorobenzyloxy)phenethyl]imidazole nitrate; melting point 179°C.
Therapeutic Function
Antibacterial, Antifungal
Isoconazole nitrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3586 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9358 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29271 | 58 |
View Lastest Price from Isoconazole nitrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-06-24 | Isoconazole nitrate USP/EP/BP
24168-96-5
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2020-05-10 | Isoconazole Nitrate
24168-96-5
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | Isoconazole nitrate
24168-96-5
|
US $1.00 / kg | 1kg | 99% | Customized | Career Henan Chemical Co |
-
- Isoconazole nitrate USP/EP/BP
24168-96-5
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
-
- Isoconazole Nitrate
24168-96-5
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Isoconazole nitrate
24168-96-5
- US $1.00 / kg
- 99%
- Career Henan Chemical Co