Phenylboronic acid
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Phenylboronic acid Properties
- Melting point:
- 216-219 °C(lit.)
- Boiling point:
- 265.9±23.0 °C(Predicted)
- Density
- 1.13±0.1 g/cm3(Predicted)
- storage temp.
- 0-6°C
- pka
- 8.83(at 25℃)
- form
- Crystalline Powder
- color
- White to off-white
- Water Solubility
- 10 g/L (20 ºC)
- Sensitive
- Hygroscopic
- Merck
- 14,1068
- BRN
- 970972
- InChIKey
- HXITXNWTGFUOAU-UHFFFAOYSA-N
- CAS DataBase Reference
- 98-80-6(CAS DataBase Reference)
- EWG's Food Scores
- 1
- FDA UNII
- L12H7B02G5
- EPA Substance Registry System
- Boronic acid, phenyl- (98-80-6)
SAFETY
- Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||||
| Hazard statements | H315-H319-H302-H335 | |||||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501 | |||||||||||
| Hazard Codes | Xn,Xi,N | |||||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||||
| Safety Statements | 22-24/25-36/37/39-26-36 | |||||||||||
| WGK Germany | 3 |
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| RTECS | CY8575000 |
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| Hazard Note | Harmful | |||||||||||
| TSCA | Yes | |||||||||||
| HazardClass | IRRITANT, MOISTURE SENSITIVE | |||||||||||
| HS Code | 29310095 | |||||||||||
| Toxicity | LD50 orl-rat: 740 mg/kg 14KTAK -,693,64 | |||||||||||
| NFPA 704 |
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Phenylboronic acid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 78181 | Phenylboronic acid purum, ≥97.0% (HPLC) | 98-80-6 | 1g | $42.7 | 2020-08-18 | Buy |
| Sigma-Aldrich | 78181 | Phenylboronic acid purum, ≥97.0% (HPLC) | 98-80-6 | 10g | $70.3 | 2020-08-18 | Buy |
| TCI Chemical | B0857 | Phenylboronic Acid (contains varying amounts of Anhydride) | 98-80-6 | 5g | $13 | 2020-06-24 | Buy |
| TCI Chemical | B0857 | Phenylboronic Acid (contains varying amounts of Anhydride) | 98-80-6 | 25g | $37 | 2020-06-24 | Buy |
| Alfa Aesar | A14257 | Benzeneboronic acid, 98+% | 98-80-6 | 10g | $30.6 | 2020-06-24 | Buy |
Phenylboronic acid Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powderUses
Reagent used for• ;Rhodium-catalyzed intramolecular amination1 • ;Pd-catalyzed direct arylation2 • ;Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles3 • ;Palladium-catalyzed stereoselective Heck-type reaction4 • ;Highly effective Palladium-catalyzed arylation Suzuki-Miyaura cross-coupling in water5 Reagent used in Preparation of• ;Ni(II) pincer complex and Pd(II) pyridoxal hydrazone metallacycles as catalysts for the Suzuki-Miyaura cross-coupling reactions6,7• ;N-type polymers for all-polymer solar cells8 •Uses
suzuki reactionUses
Phenylboronic acid and its derivatives form complexes with polyol compounds such as saccharides and poly(vinyl alcohol) (PVA). Glucose-sensitive hydrogels can be prepared by using phenylhoronic acid as a ligand for target glucose. For example. a copolymer with phenylboronic acid moieties was synthesized by copolymerization of 4V-vinyl-2-pyrrolidone (NVP) and 3-(acryl- amide)phcnylhoronic acid (PBA). The complexes between the NVP-PBA copolymer and PVA enable us to construct glucose-sensitive insulin release systems because the complexes dissociated in response to the glucose concentration.This phenylboronic acid is soluble in water and the coupling reaction can even be carried out in water. It is compatible with many organic substituents such as esters, ketones, alcohols, etc. which would prohibit the use of Grignard reagents in coupling reactions.
Uses
Phenylboronic Acid is a compound used in organic synthesis of various pharmaceutical goods.Phenylboronic acid (PBA) and its derivatives can bind sugars and other diol compounds to form cyclic boronate esters. These esters bear negative charges. Due to this reaction, sugars can be detected by means of electrochemical and optical techniques.
PBA modified electrodes have been constructed as reagentless electrochemical sensors. There, PBA is absorbed on the electrode surface either as a self- assembled monolayer film ore a polymer thin film. Basically, for optical detection techniques for the detection of sugars, PBA is modified with a chromophore that should change its properties on reaction with a sugar.
Reaction of Phenylboronic acid with a sugar
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 4, p. 68, 1963The Journal of Organic Chemistry, 49, p. 5237, 1984 DOI: 10.1021/jo00200a045
Safety Profile
Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion.Mildly toxic by skin contact. When heated to decomposition it emitsacrid smoke and irritating fumes.Phenylboronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-AMINOBIPHENYL
3-PHENYLBENZYLAMINE
1-phenyl-3-(trifluoromethyl)pyrazole-4-carboxylic acid
Dimidium bromide
3-AMINO-6-PHENYLPYRIDAZINE
2-Aminophenylboronic acid
4-Aminobiphenyl
Phenylboronic acid Suppliers
Global( 499)Suppliers
| Supplier | Tel | Fax | Country | ProdList | Advantage | |
|---|---|---|---|---|---|---|
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 |
021-60451683 | act@arborchemical.com | CHINA | 906 | 58 |
| Puyang Huicheng Electronic Materials Co., Ltd. | 03938910800 |
info@huichengchem.com | CHINA | 477 | 58 | |
| Springchem New Material Technology Co.,Limited | 86-21-51752791 |
86-21-51752789 | info@spring-chem.com | China | 1870 | 57 |
| Henan DaKen Chemical CO.,LTD. | +86-371-55531817 |
info@dakenchem.com | CHINA | 21842 | 58 | |
| Henan Tianfu Chemical Co.,Ltd. | 0371-55170693 |
0371-55170693 | info@tianfuchem.com | CHINA | 22625 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 |
+86-021-57951555 | jack.li@time-chemicals.com | CHINA | 1365 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3014 | 60 | |
| ATK CHEMICAL COMPANY LIMITED | +86 21 5161 9050/ 5187 7795 |
+86 21 5161 9052/ 5187 7796 | ivan@atkchemical.com | CHINA | 24886 | 60 |
| career henan chemical co | +86-371-86658258 |
sales@coreychem.com | CHINA | 30039 | 58 | |
| QINGDAO HONG JIN CHEMCIAL CO.,LTD. | +86 532 83657313 |
hjt@hong-jin.com | CHINA | 230 | 58 |
Related articles
- Correlational research of Phenylboronic acid
- Phenylboronic acid or benzeneboronic acid, abbreviated as PhB(OH)2 where Ph is the phenyl group C6H5-, is a boronic acid conta....
- Nov 12，2019
View Lastest Price from Phenylboronic acid manufacturers
| Image | Release date | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-08-26 |
Phenylboronic acid 98-80-6 |
US $30.00 / KG | 1KG | 98%min | 5000 Kilogram/Kilograms per Month | Hebei Runbin Biotechnology Co. LTD | |
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2020-07-07 |
Phenylboronic acid 98-80-6 |
US $100.00 / KG | 1KG | 99.7% | 10000 Kilogram/Kilograms per Month | Hebei Xibaijie Biotechnology Co., Ltd. | |
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2020-06-03 |
cas 98-80-6 Phenylboronic acid fiona 98-80-6 |
US $1.00 / g | 1g | 99% | 10 mt | Hebei Guanlang Biotechnology Co., Ltd. |
98-80-6(Phenylboronic acid)Related Search:
3-(2-METHYL-1,3-DIOXOLAN-2-YL)PHENYLBORONIC ACID 3-(3-ETHOXY-3-OXOPROPYLCARBAMOYL)PHENYLBORONIC ACID 3-Formylphenylboronic acid 2-[(1',2',3',4'-TETRAHYDRO-5-NAPHTHYLOXY)METHYL]PHENYLBORONIC ACID 3-Carboxyphenylboronic acid 4-Fluorobenzeneboronic acid 3-Tolylboronic acid 4-Chlorophenylboronic acid 3-(DANSYLAMINO)PHENYLBORONIC ACID 3-Methoxyphenylboronic acid 4-Tolylboronic acid Ethyl 2-(Chlorosulfonyl)acetate Glycine Citric acid Phenethylboronic acid Folic acid phosphoric acid Ascoric Acid
- BIO-FARMA BF001405
- BORONIC ACID, PHENYL-
- BENZENEBORONIC ACID
- BENZENEBORONIC ACID/ANHYDRIDE
- DIHYDROXYPHENYLBORANE
- Phenylboronic acid, 98+%
- Phenylboronic acid C6H5B(OH)2
- Phenylboronicacid,min.97%
- RARECHEM AH PB 0250
- PHENYLBORIC ACID
- PHENYLBORON DIHYDROXIDE
- PHENYLBORONIC ACID
- Phenyboronic acid Benzenebcronic acid
- Benzenebcronic acid
- Phenyboronic acid
- Phenylboronic Acid (PBA)
- PhenylboricAcid>95%
- Benzeneboronic acid (may contain anhydride), 98%
- AKOS BRN-0133
- Benzeneboronicacid,98+%
- Boronic acid,pheny
- phenyboronic
- phenyl-boronicaci
- phenyldihydroxyborane
- t-500
- usafbo-2
- Benzenboronic acid
- Phenylboronic Acid (contains varying amounts of Anhydride)
- Phenylboric Acid: (Benzeneboronic acid)
- Phenylboronic acid, min. 97%
- Phenylboranic acid
- Phenylboronic acid, May contain varying amounts of anhydride, 97%
- Phenylboronic acid, may contain varying amounts of anhydride, 98+%
- phenylboronic acid(SALTDATA: H2O)
- Phenylboronic acid, 98+%, May contain varying aMounts of anhydride
- Phenylboronic acid, 98+% 10GR
- Phenylboronic acid, 98+% 50GR
- Phenylboronic Acid (95%)
- NSC 66487
- BENZENEBORONIC ACID; PHENYLBORON DIHYDROXIDE
- Phenylbronicacid
- cas 98-80-6 Phenylboronic acid fiona
- Phenylboronic acid puruM, >=97.0% (HPLC)
- Phenylboronic acid SynonyMs Benzeneboronic acid
- Phenylboronic acid Benzeneboronic acid
- CAS:98-80-6
- acidephenylborique
- borophenylicacid
- kyselinafenylborita
- [phenyl-U-14C6]phenylboronic acid
- Phenylboronic acid D5
- 98-80-6
- C6H7BO2
- C6H5BOH2
- Organometallic Reagents
- Boronic Acids and Derivatives
- Aryl
- GC Derivatizing Reagents
