3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
- CAS No.
- 22246-18-0
- Chemical Name:
- 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
- Synonyms
- 7-HYDROXY-3,4-DIHYDROQUINOLIN-2(1H)-ONE;7-HYDROXY-3,4-DIHYDROCARBOSTYRIL;7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE;7-HYDROXY-3,4-DIHYDRO-1H-QUINOLIN-2-ONE;7-Hydroxy-3;AURORA KA-4813;Aripiprazole Imp.A;3,4-Dihydro-7-hydrox;7-Hydroxy carbostyril;Aripiprazole Impurity 13
- CBNumber:
- CB5325629
- Molecular Formula:
- C9H9NO2
- Molecular Weight:
- 163.17
- MDL Number:
- MFCD06410891
- MOL File:
- 22246-18-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 97% | 675369 | 1g | $28.5 |
| 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone >98.0%(HPLC)(N) | D3599 | 5g | $20 |
| 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone >98.0%(HPLC)(N) | D3599 | 25g | $43 |
| 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one | D449145 | 5g | $135 |
| 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone | FD22021 | 50g | $80 |
| More product size | |||
| Melting point | 233-237 °C |
|---|---|
| Boiling point | 403.7±45.0 °C(Predicted) |
| Density | 1.282±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.60±0.20(Predicted) |
| form | Solid |
| color | Pale Yellow |
| InChI | InChI=1S/C9H9NO2/c11-7-3-1-6-2-4-9(12)10-8(6)5-7/h1,3,5,11H,2,4H2,(H,10,12) |
| InChIKey | LKLSFDWYIBUGNT-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=CC(O)=C2)CCC1=O |
| CAS DataBase Reference | 22246-18-0(CAS DataBase Reference) |
| FDA UNII | VFU6XCR3Q3 |
| UNSPSC Code | 41116100 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29334900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 675369 | 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 97% | 22246-18-0 | 1g | $28.5 | 2026-04-30 | Buy |
| TCI Chemical | D3599 | 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone >98.0%(HPLC)(N) | 22246-18-0 | 5g | $20 | 2026-04-30 | Buy |
| TCI Chemical | D3599 | 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone >98.0%(HPLC)(N) | 22246-18-0 | 25g | $43 | 2026-04-30 | Buy |
| TRC | D449145 | 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one | 22246-18-0 | 5g | $135 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD22021 | 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone | 22246-18-0 | 50g | $80 | 2021-12-16 | Buy |
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Chemical Properties,Uses,Production
Description
3,4-Dihydro-7-hydroxy-2 (1H)-quinolinone is a useful organic and pharmaceutical intermediate. It can be used as the precursor of aripiprazole1, which is an antipsychotic medication. It is also an antitumor agent and hydroxyindole analog inhibitor tyrosinase melanoma.
Chemical Properties
Pale Yellow Powder
Uses
3,4-Dihydro-7-hydroxyquinoline-2(1H)-one (Aripiprazole EP Impurity A) is an antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000).
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | sales@ichemie.com | China | 1006 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
View Lastest Price from 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-30 | 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
22246-18-0
|
US $23.00 / kg | 1kg | 99% | 20MT | Jinan Finer Chemical Co., Ltd | |
![]() |
2026-04-30 | 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
22246-18-0
|
US $0.00-0.00 / Kg/Drum | 1KG | 98%min | 1000kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2026-04-20 | 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
22246-18-0
|
US $29.00 / mg | 99.20% | 10g | TargetMol Chemicals Inc. |
-

- 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
22246-18-0
- US $23.00 / kg
- 99%
- Jinan Finer Chemical Co., Ltd
-

- 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
22246-18-0
- US $0.00-0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone
22246-18-0
- US $29.00 / mg
- 99.20%
- TargetMol Chemicals Inc.
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