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Remdesivir

CAS No.
1809249-37-3
Chemical Name:
Remdesivir
Synonyms
2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate;GS5734;L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 2-ethylbutyl ester, 6-ester with 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile;Remdesivir (GS-5734);(S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate;Ragoli;Remdesivir;Remdesivir API;Remdesivir 99%;Redecivir (API)
CBNumber:
CB53339887
Molecular Formula:
C27H35N6O8P
Molecular Weight:
602.58
MDL Number:
MFCD31657351
MOL File:
1809249-37-3.mol

Remdesivir Properties

Density 1.47±0.1 g/cm3(Predicted)
pka 12.00±0.70(Predicted)
FDA UNII 3QKI37EEHE

Remdesivir price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 30354 Remdesivir 1809249-37-3 5mg $96 2022-04-27 Buy
Cayman Chemical 30354 Remdesivir ≥98% 1809249-37-3 10mg $163 2022-04-27 Buy
Cayman Chemical 30354 Remdesivir ≥98% 1809249-37-3 50mg $568 2022-04-27 Buy
Cayman Chemical 30354 Remdesivir ≥98% 1809249-37-3 100mg $919 2022-04-27 Buy
Cayman Chemical 30354 Remdesivir 1809249-37-3 1mg $315 2021-12-16 Buy
Product number Packaging Price Buy
30354 5mg $96 Buy
30354 10mg $163 Buy
30354 50mg $568 Buy
30354 100mg $919 Buy
30354 1mg $315 Buy

Remdesivir Chemical Properties,Uses,Production

Mechanism of action

As an adenosine nucleoside triphosphate analog (GS-443902),the active metabolite of remdesivir interferes with the action of viral RNA-dependent RNA polymerase and evades proofreading by viral exoribonuclease (ExoN), causing a decrease in viral RNA production.In some viruses, such as the respiratory syncytial virus, it causes the RNA-dependent RNA polymerases to pause, but its predominant effect (as in Ebola) is to induce an irreversible chain termination. Unlike with many other chain terminators, this is not mediated by preventing addition of the immediately subsequent nucleotide, but is instead delayed, occurring after five additional bases have been added to the growing RNA chain.For the RNA-Dependent RNA Polymerase of MERS-CoV, SARS-CoV-1, and SARS-CoV-2, arrest of RNA synthesis occurs after incorporation of three additional nucleotides.Hence, remdesivir is classified as a direct-acting antiviral agent that works as a delayed chain terminator.

side effect

The most common adverse effects in people treated with remdesivir were respiratory failure and blood biomarkers of organ impairment, including low albumin, low potassium, low count of red blood cells, low count of thrombocytes, and elevated bilirubin (jaundice).Other reported adverse effects include gastrointestinal distress, elevated transaminase levels in the blood (liver enzymes), infusion site reactions, and electrocardiogram abnormalities. Remdesivir may cause infusion‐related reactions, including low blood pressure, nausea, vomiting, sweating or shivering.

Description

Remdesivir, sold under the brand name Veklury,is a broad-spectrum antiviral medication developed by the biopharmaceutical company Gilead Sciences.It is administered via injection into a vein.During the COVID-19 pandemic, remdesivir was approved or authorized for emergency use to treat COVID-19 in around 50 countries.Updated guidelines from the World Health Organization in November 2020 include a conditional recommendation against the use of remdesivir for the treatment of COVID-19.

Uses

Remdesivir was originally developed to treat hepatitis C,and was subsequently investigated for Ebola virus disease and Marburg virus infections before being studied as a post-infection treatment for COVID-19.

Remdesivir Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 257)Suppliers
Supplier Tel Email Country ProdList Advantage
Echemi Group
86-18905328650 18905328650 pharma@echemi.com CHINA 215 58
Shenzhen Nexconn Pharmatechs Ltd
15013857715 admin@nexconn.com CHINA 3004 58
Hangzhou Cherry Pharmaceutical Technology Co.,ltd
0571-81636070 info@cherrypharmatech.com CHINA 275 58
Baoji Guokang Bio-Technology Co., Ltd.
0917-3909592 13892490616 gksales1@gk-bio.com CHINA 9412 58
Hangzhou Huarong Pharm Co., Ltd.
571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.
+8618829239519 sales06@tgybio.com China 995 58
BAODING STORD IMPORT AND EXPORT CO.,LTD
+8618603329229 luis.manager113@foxmail.com China 293 58
Hubei Ipure Biology Co., Ltd
+8618062405514 ada@ipurechemical.com China 10352 58
Qiuxian Baitai New Material Co., LTD
+8619932103556 sale2@hbyalin.com China 1691 58
Zhengzhou Anhuida Chemical Co., Ltd
+8615903659408 admin@ahdchem.com China 297 58

View Lastest Price from Remdesivir manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2022-09-23 Remdesivir
1809249-37-3
US $0.00 / kg 1kg 99% 1000kg henan kanbei chemical co.,ltd
2022-09-15 Remdesivir
1809249-37-3
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
2022-09-12 Remdesivir
1809249-37-3
US $200.00-175.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biological Technology Co., Ltd
  • Remdesivir
    1809249-37-3
  • US $0.00 / kg
  • 99%
  • henan kanbei chemical co.,ltd
  • Remdesivir
    1809249-37-3
  • US $0.00-0.00 / KG
  • 98%
  • Henan Aochuang Chemical Co.,Ltd.
  • Remdesivir
    1809249-37-3
  • US $200.00-175.00 / KG
  • 99%
  • Hebei Lingding Biological Technology Co., Ltd
Remdesivir Remdesivir API Remdesivir Powder high purity Remdesivir Redecivir (API) Remdesivir liquid Remdesivir lypholized powder remdesivir producing remdesivir producing The finished product Remdesivir EP/USP/BP Remdesivir*(Available for selected markets) GS5734Remdesivir 2-ethylbutyl ((((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-6-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate Ragoli 2-ethylbutyl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-{4-aminopyrrolo[2,1- f][1,2,4]triazin-7-yl}-5-cyano-3,4-dihydroxyoxolan- 2-yl]methoxy}(phenoxy)phosphoryl]amino}propan oate Remdesivir-13C6Q: What is Remdesivir-13C6 Q: What is the CAS Number of Remdesivir-13C6 Remdesivir 15N,13C3, D4Q: What is Remdesivir 15N,13C3, D4 Q: What is the CAS Number of Remdesivir 15N,13C3, D4 Remdesivir 15N,13C3Q: What is Remdesivir 15N,13C3 Q: What is the CAS Number of Remdesivir 15N,13C3 Remdesivir 99% 2-ethylbutyl((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-c yano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alanin ate GS5734 L-Alanine, N-[(S)-hydroxyphenoxyphosphinyl]-, 2-ethylbutyl ester, 6-ester with 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile Remdesivir (GS-5734) 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate (S)-2-ethylbutyl2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 1809249-37-3 210-62-4 1809249-37-2 C27H35N6O8P Pharmaceutical API NMN