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11-KETO FLUPROSTENOL

CAS No.
62145-07-7
Chemical Name:
11-KETO FLUPROSTENOL
Synonyms
11-KETO FLUPROSTENOL;Travoprost Impurity 22;FLUPROSTENOL PROSTAGLANDIN D2;Travoprost Impurity 17(11-keto Fluprostenol);11-OXO-9ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-3-oxocyclopentyl]-, (5Z)-
CBNumber:
CB5334872
Molecular Formula:
C23H27F3O6
Molecular Weight:
456.45
MDL Number:
MFCD05863541
MOL File:
Mol file
Last updated:2023-06-08 09:03:09

11-KETO FLUPROSTENOL Properties

Boiling point 627.3±55.0 °C(Predicted)
Density 1.331±0.06 g/cm3(Predicted)
solubility PBS (7.2): 29 mg/ml
pka 4.76±0.10(Predicted)

11-KETO FLUPROSTENOL price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 62145-07-7 1mg $72 2024-03-01 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 62145-07-7 5mg $319 2024-03-01 Buy
Cayman Chemical 16783 11-keto Fluprostenol ≥98% 62145-07-7 10mg $565 2024-03-01 Buy
AK Scientific 6444DD (Z)-7-[(1R,2R,5S)-5-Hydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3-oxocyclopentyl]hept-5-enoicacid 62145-07-7 5mg $452 2021-12-16 Buy
Product number Packaging Price Buy
16783 1mg $72 Buy
16783 5mg $319 Buy
16783 10mg $565 Buy
6444DD 5mg $452 Buy

11-KETO FLUPROSTENOL Chemical Properties,Uses,Production

Description

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF and acts primarily through the FP receptor.1 Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.2

Definition

ChEBI: 11-keto Fluprostenol is a prostanoid.

References

1. Dukes, M., Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F Nature 250(464),330-331(1974).
2. Monneret, G., Cossette, C., Gravel, S., et al. 15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils J. Pharmacol. Exp. Ther. 304(1),349-355(2003).

11-KETO FLUPROSTENOL Preparation Products And Raw materials

Raw materials

Preparation Products

11-KETO FLUPROSTENOL Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17982 56
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Guangzhou Dreampharm Biotechnology Co., Ltd. 17825480238 3008233717@qq.com China 9844 12
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14253 58
Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 sales@dmstandards.com China 10951 58
Scinova Biotech(Guangzhou) Co., Ltd. 13268215580 scinova_sales@163.com China 7026 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
FLUPROSTENOL PROSTAGLANDIN D2 11-OXO-9ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID Travoprost Impurity 17(11-keto Fluprostenol) Travoprost Impurity 22 5-Heptenoic acid, 7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-3-oxocyclopentyl]-, (5Z)- 11-KETO FLUPROSTENOL 62145-07-7