N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester)
- CAS No.
- 2112737-19-4
- Chemical Name:
- N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester)
- Synonyms
- IUN 37194;N-(Aminooxy-PEG3)-N-bis(PEG4-Boc);N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester);4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[2-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]ethyl]-, 1,31-bis(1,1-dimethylethyl) ester;tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethyl-[2-[2-[2-[2-(3-tert-butoxy-3-oxo-propoxy)ethoxy]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
- CBNumber:
- CB53373670
- Molecular Formula:
- C38H76N2O16
- Molecular Weight:
- 817.01
- MDL Number:
- MFCD30730364
- MOL File:
- 2112737-19-4.mol
N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) Chemical Properties,Uses,Production
Description
N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) is a branched aminooxy linker. It can react with aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl ester group can be hydrolyzed under acidic conditions. The hydrophilic PEG linkers increase the water solubility of the compound. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32262 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38659 | 58 | |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55017 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85563444 18351873721 | purchase@synzest.com | China | 10434 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 10001 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |
View Lastest Price from N-(Aminooxy-PEG3)-N-bis(PEG4-t-butyl ester) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)
2112737-19-4
|
US $39.00 / mg | 10g | TargetMol Chemicals Inc. | |||
 |
2024-03-29 | N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)
2112737-19-4
|
US $0.00 / mg | 250mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)
2112737-19-4
- US $39.00 / mg
- TargetMol Chemicals Inc.
-
- N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)
2112737-19-4
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.