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4-Methylsulphonylacetophenone

CAS No.
10297-73-1
Chemical Name:
4-Methylsulphonylacetophenone
Synonyms
4-(Methyl Sulfonyl);Etoricoxib USP RC A;Etocoxib impurity 1;4'-Mesylacetophenone;4-Methylsulphonylace;Etoricoxib impurity C;Acetophenone Impurity 2;P-METHYLSULFONYLACETOPHENONE;4-METHYLSULFONYLACETOPHENONE;Etoricoxib Related CoMpound A
CBNumber:
CB5339796
Molecular Formula:
C9H10O3S
Molecular Weight:
198.24
MDL Number:
MFCD00025072
MOL File:
10297-73-1.mol
MSDS File:
SDS
Last updated:2026-01-13 11:22:09
Product description Number Pack Size Price
4′-(Methylsulfonyl)acetophenone 97% 549304 25g $97.8
4'-(Methylsulfonyl)acetophenone >98.0%(GC) M1678 25g $61
4'-(Methylsulfonyl)acetophenone >98.0%(GC) M1678 250g $376
4-ACETYLPHENYL METHYL SULPHONE 98% 56004 25G $47
4-ACETYLPHENYL METHYL SULPHONE 98% 56004 100G $117
More product size

4-Methylsulphonylacetophenone Properties

Melting point 126-129 °C(lit.)
Boiling point 305.56°C (rough estimate)
Density 1.3339 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Crystalline Powder or Needles
color White to slightly yellow
InChI InChI=1S/C9H10O3S/c1-7(10)8-3-5-9(6-4-8)13(2,11)12/h3-6H,1-2H3
InChIKey KAVZYDHKJNABPC-UHFFFAOYSA-N
SMILES C(=O)(C1=CC=C(S(C)(=O)=O)C=C1)C
CAS DataBase Reference 10297-73-1(CAS DataBase Reference)
FDA UNII 9D65F147ZN
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29144000
Storage Class 13 - Non Combustible Solids
NFPA 704
1
0 0

4-Methylsulphonylacetophenone price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 549304 4′-(Methylsulfonyl)acetophenone 97% 10297-73-1 25g $97.8 2022-05-15 Buy
TCI Chemical M1678 4'-(Methylsulfonyl)acetophenone >98.0%(GC) 10297-73-1 25g $61 2026-04-30 Buy
TCI Chemical M1678 4'-(Methylsulfonyl)acetophenone >98.0%(GC) 10297-73-1 250g $376 2026-04-30 Buy
AstaTech 56004 4-ACETYLPHENYL METHYL SULPHONE 98% 10297-73-1 25G $47 2026-04-30 Buy
AstaTech 56004 4-ACETYLPHENYL METHYL SULPHONE 98% 10297-73-1 100G $117 2026-04-30 Buy
Product number Packaging Price Buy
549304 25g $97.8 Buy
M1678 25g $61 Buy
M1678 250g $376 Buy
56004 25G $47 Buy
56004 100G $117 Buy

4-Methylsulphonylacetophenone Chemical Properties,Uses,Production

Chemical Properties

white to slightly yellow cryst. powder or needles

Uses

4′-(Methylsulfonyl)acetophenone may be used in the synthesis of:

  • 3-(4-Methylsulfonylphenyl)-4-phenyl-2(5H)-furanone with potent apoptosis-inducing ability.
  • Bromo-4-methylsulfonylacetophenone, an intermediate for preparing DL-threo-2-dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol.
  • 1-N-Substituted-3,5-diphenyl-2-pyrazoline derivatives, which show promising anti-inflammatory activity.

Uses

4-(Methylsulfonyl)acetophenone is an impurity of Etoricoxib (E934100), which is a specific inhibitor of COX-2.

4-Methylsulphonylacetophenone Preparation Products And Raw materials

Global( 303)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29640 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29819 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10821 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Hebei Zhanyao Biotechnology Co. Ltd
15369953316 +8615369953316 admin@zhanyaobio.com China 2123 58
RongNa Biotechnology Co.,Ltd
+86-86-13583358881 +8618560316533 Brad@rongnabiotech.com China 3364 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52705 58

View Lastest Price from 4-Methylsulphonylacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methylsulphonylacetophenone pictures 2026-05-02 4-Methylsulphonylacetophenone
10297-73-1
0.99 RongNa Biotechnology Co.,Ltd
4-Methylsulphonylacetophenone pictures 2025-12-01 4-Methylsulphonylacetophenone
10297-73-1
US $0.00 / KG 1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Methylsulphonylacetophenone pictures 2025-04-04 4-Methylsulphonylacetophenone
10297-73-1
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
4-Methyi Sulfonyl Acetophenone, Rofecoxib, (4-Methanesulphonylphenyl)-ethanone 4'-(Methylsulphonyl)acetophenone 98% 4-(METHYLSULPHONYL)ACETOPHENONE 98+% 1-(4-(methylsufonyl)phenyl)ethanone Ethanone, 1-[4-(methylsulfonyl)phenyl]- 4'-Mesylacetophenone 4-Methylsulphonylacetophenone,95% 4-Methylsulphonylace 4'-(Methylsulfonyl)acetophenone, 97+% Etoricoxib Related CoMpound A 4'-(Methylsulfonyl)acetophenone 97% Etoricoxib USP Related Compound A P-METHYLSULFONYLACETOPHENONE Etoricoxib impurity C 1-[4-(METHYLSULFONYL)PHENYL]-1-ETHANONE 1-[4-(METHYLSULFONYL)PHENYL]ETHAN-1-ONE 1-(4-(METHYLSULFONYL)PHENYL)ETHANONE 1-(4-METHANESULFONYL-PHENYL)-ETHANONE 4'-(METHYLSULPHONYL)ACETOPHENONE 4-(METHYLSULPHONYL)ACETOPHENONE 4-METHYLSULFONYLACETOPHENONE 4-METHANESULFONYLACETOPHENONE 4-ACETYLPHENYL METHYL SULPHONE 4-ACETOPHENONE METHYL SULFONE 1-[4-(methylsulphonyl)phenyl]ethan-1-one 4-(Methyl Sulfonyl) 4-MetylSulphonileAcetophenone 4'-(Methylsulfonyl)acetophenone> Etoricoxib USP RC A Acetophenone Impurity 2 Etocoxib impurity 1 4'-(Methylsulfonyl)acetophenone 4'-Methylsulphonylacetophenone 1,4-methylsulfonile Phenyl Ethanone 4′-(Methylsulfonyl)acetophenone, CAS 10297-73-1 4'-(Methylsulfonyl)acetophenon 4-(METHYLSULPHONYL)ACETOPHChemicalbookENONE98+% 10297-73-1 CH3SO2C6H4COCH3 C9H10O3S Building Blocks C9 Carboxylic Acids Carbonyl Compounds Organic Building Blocks Sulfur Compounds Sulfones Osteoarthritis and Rheumatoid Arthritis bc0001