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4-Methylsulphonylacetophenone

CAS No.
10297-73-1
Chemical Name:
4-Methylsulphonylacetophenone
Synonyms
4-(Methyl Sulfonyl);Etoricoxib USP RC A;Etocoxib impurity 1;4'-Mesylacetophenone;4-Methylsulphonylace;Etoricoxib impurity C;Acetophenone Impurity 2;P-METHYLSULFONYLACETOPHENONE;4-METHYLSULFONYLACETOPHENONE;Etoricoxib Related CoMpound A
CBNumber:
CB5339796
Molecular Formula:
C9H10O3S
Molecular Weight:
198.24
MDL Number:
MFCD00025072
MOL File:
10297-73-1.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

4-Methylsulphonylacetophenone Properties

Melting point 126-129 °C(lit.)
Boiling point 305.56°C (rough estimate)
Density 1.3339 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Crystalline Powder or Needles
color White to slightly yellow
CAS DataBase Reference 10297-73-1(CAS DataBase Reference)
FDA UNII 9D65F147ZN

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29144000
NFPA 704
1
0 0

4-Methylsulphonylacetophenone price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 549304 4′-(Methylsulfonyl)acetophenone 97% 10297-73-1 25g $97.8 2022-05-15 Buy
TCI Chemical M1678 4'-(Methylsulfonyl)acetophenone >98.0%(GC) 10297-73-1 25g $84 2024-03-01 Buy
TCI Chemical M1678 4'-(Methylsulfonyl)acetophenone >98.0%(GC) 10297-73-1 250g $522 2024-03-01 Buy
Alfa Aesar H54072 4'-(Methylsulfonyl)acetophenone, 97+% 10297-73-1 1g $28.65 2024-03-01 Buy
Alfa Aesar H54072 4'-(Methylsulfonyl)acetophenone, 97+% 10297-73-1 5g $89.65 2024-03-01 Buy
Product number Packaging Price Buy
549304 25g $97.8 Buy
M1678 25g $84 Buy
M1678 250g $522 Buy
H54072 1g $28.65 Buy
H54072 5g $89.65 Buy

4-Methylsulphonylacetophenone Chemical Properties,Uses,Production

Chemical Properties

white to slightly yellow cryst. powder or needles

Uses

4′-(Methylsulfonyl)acetophenone may be used in the synthesis of:

  • 3-(4-Methylsulfonylphenyl)-4-phenyl-2(5H)-furanone with potent apoptosis-inducing ability.
  • Bromo-4-methylsulfonylacetophenone, an intermediate for preparing DL-threo-2-dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol.
  • 1-N-Substituted-3,5-diphenyl-2-pyrazoline derivatives, which show promising anti-inflammatory activity.

Uses

4-(Methylsulfonyl)acetophenone is an impurity of Etoricoxib (E934100), which is a specific inhibitor of COX-2.

4-Methylsulphonylacetophenone Preparation Products And Raw materials

Global( 289)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10828 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58

View Lastest Price from 4-Methylsulphonylacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methylsulphonylacetophenone pictures 2022-10-11 4-Methylsulphonylacetophenone
10297-73-1
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
4'-Methylsulphonyl Acetophenone pictures 2021-10-30 4'-Methylsulphonyl Acetophenone
10297-73-1
US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd
	4-Methylsulphonylacetophenone pictures 2019-07-06 4-Methylsulphonylacetophenone
10297-73-1
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co

4-Methylsulphonylacetophenone Spectrum

4-Methyi Sulfonyl Acetophenone, Rofecoxib, (4-Methanesulphonylphenyl)-ethanone 4'-(Methylsulphonyl)acetophenone 98% 4-(METHYLSULPHONYL)ACETOPHENONE 98+% 1-(4-(methylsufonyl)phenyl)ethanone Ethanone, 1-[4-(methylsulfonyl)phenyl]- 4'-Mesylacetophenone 4-Methylsulphonylacetophenone,95% 4-Methylsulphonylace 4'-(Methylsulfonyl)acetophenone, 97+% Etoricoxib Related CoMpound A 4'-(Methylsulfonyl)acetophenone 97% Etoricoxib USP Related Compound A P-METHYLSULFONYLACETOPHENONE Etoricoxib impurity C 1-[4-(METHYLSULFONYL)PHENYL]-1-ETHANONE 1-[4-(METHYLSULFONYL)PHENYL]ETHAN-1-ONE 1-(4-(METHYLSULFONYL)PHENYL)ETHANONE 1-(4-METHANESULFONYL-PHENYL)-ETHANONE 4'-(METHYLSULPHONYL)ACETOPHENONE 4-(METHYLSULPHONYL)ACETOPHENONE 4'-(METHYLSULFONYL)ACETOPHENONE 4-METHYLSULFONYLACETOPHENONE 4-METHANESULFONYLACETOPHENONE 4-ACETYLPHENYL METHYL SULPHONE 4-ACETOPHENONE METHYL SULFONE 1-[4-(methylsulphonyl)phenyl]ethan-1-one 4-(Methyl Sulfonyl) 4-MetylSulphonileAcetophenone 4'-(Methylsulfonyl)acetophenone> Etoricoxib USP RC A Acetophenone Impurity 2 Etocoxib impurity 1 4'-(Methylsulfonyl)acetophenone 10297-73-1 CH3SO2C6H4COCH3 C9H10O3S Building Blocks C9 Carboxylic Acids Carbonyl Compounds Organic Building Blocks Sulfur Compounds Sulfones Osteoarthritis and Rheumatoid Arthritis bc0001