ChemicalBook >> CAS DataBase List >>Bendamustine
Bendamustine
- CAS No.
- 16506-27-7
- Chemical Name:
- Bendamustine
- Synonyms
- 4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid;Bendamustine;4-(5-(Bis(2-chloroethyl);-1-methyl-1H-benzo[d]imidazol-2-yl);5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;1H-BenziMidazole-2-butanoicacid, 5-[bis(2-chloroethyl)aMino]-1-Methyl-;alkylating,SDX-105,inhibit,DNA Alkylator/Crosslinker,antimetabolite,purine,anticancer,Apoptosis,Bendamustine,SDX 105,Inhibitor,DNA;BendamustineQ: What is Bendamustine Q: What is the CAS Number of Bendamustine Q: What is the storage condition of Bendamustine Q: What are the applications of Bendamustine
- CBNumber:
- CB5340488
- Molecular Formula:
- C16H21Cl2N3O2
- Molecular Weight:
- 358.26
- MDL Number:
- MFCD00866481
- MOL File:
- 16506-27-7.mol
Last updated:2023-05-21 10:59:17
| Boiling point | 585.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | -20°C, protect from light |
| solubility | DMSO : 100 mg/mL (279.13 mM; Need ultrasonic) |
| pka | 4.50±0.10(Predicted) |
| FDA UNII | 9266D9P3PQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360-H341-H351-H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501 |
Bendamustine price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B132558 | Bendamustine | 16506-27-7 | 100mg | $290 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005688 | BENDAMUSTINE 95.00% | 16506-27-7 | 10MG | $409.38 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005688 | BENDAMUSTINE 95.00% | 16506-27-7 | 1G | $1338 | 2021-12-16 | Buy |
| Labseeker | SC-19231 | Bendamustine 98 | 16506-27-7 | 1g | $417 | 2021-12-16 | Buy |
| Chemenu | CM161908 | 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoicacid 95% | 16506-27-7 | 1g | $833 | 2021-12-16 | Buy |
Bendamustine Chemical Properties,Uses,Production
Uses
Treatment of hematologic cancer, especially non-Hodgkin’s lymphoma.
Definition
ChEBI: Bendamustine is a member of benzimidazoles.
brand name
Ribomustine (Amcis AG, Switzerland).
Enzyme inhibitor
This nitrogen mustard and anticancer drug (FWfree-acid = 358.26 g/mol; CAS 16506-27-7), also known by its code name SDX-105, its trade names Treanda?, Treakisym?, Ribomustin?, and Levact?, as well as by its systematic name 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2- yl]butanoic acid, is a relatively nonspecific DNA alkylating agent that causes intra- and inter-strand cross-links. Bendamustine is used in the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, nonHodgkin’s lymphoma, multiple myeloma and lung cancer. Pharmacokinetics: After intravenous infusion, >95% of the drug becomes protein-bound, mainly to albumin; however, only free bendamustine is active. Bendamustine is metabolized by liver cytochrome p450, and elimination (renal) is biphasic, with an initial half-life of 6–10 minutes and a terminal half-life of approximately 30 minutes.
Bendamustine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 107)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
View Lastest Price from Bendamustine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-05 | Bendamustine
16506-27-7
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Bendamustine
16506-27-7
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
16506-27-7(Bendamustine)Related Search:
5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid
5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid
Bendamustine
-1-methyl-1H-benzo[d]imidazol-2-yl)
4-(5-(Bis(2-chloroethyl)
1H-BenziMidazole-2-butanoicacid, 5-[bis(2-chloroethyl)aMino]-1-Methyl-
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
BendamustineQ: What is
Bendamustine Q: What is the CAS Number of
Bendamustine Q: What is the storage condition of
Bendamustine Q: What are the applications of
Bendamustine
4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid
alkylating,SDX-105,inhibit,DNA Alkylator/Crosslinker,antimetabolite,purine,anticancer,Apoptosis,Bendamustine,SDX 105,Inhibitor,DNA
16506-27-7
C16H21Cl2N3O2
C15H19Cl2N3O2