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4-Aminohippuric acid

CAS No.
61-78-9
Chemical Name:
4-Aminohippuric acid
Synonyms
PAH;P-AMINOHIPPURIC ACID;POLYNUCLEAR AROMATIC HYDROCARBONS;paha;Nefrotest;N-glycine;Aminohippuric;pah(aminoacid);AKOS BBS-00006940;p-amino-hippuricaci
CBNumber:
CB5348161
Molecular Formula:
C9H10N2O3
Molecular Weight:
194.19
MDL Number:
MFCD00007890
MOL File:
61-78-9.mol
MSDS File:
SDS
Last updated:2023-11-02 14:28:45

4-Aminohippuric acid Properties

Melting point 199-200 °C (dec.)(lit.)
Boiling point 330.62°C (rough estimate)
Density 1.356
refractive index 1.5600 (estimate)
storage temp. Store below +30°C.
solubility DMF: 33 mg/ml; DMF:PBS (pH7.2) (1:30): 0.03 mg/ml; DMSO: 20 mg/ml
pka pKa 3.8 (Uncertain)
form Crystalline Powder
color Off-white to grayish
PH 3.0-3.5 (20g/l, H2O, 20℃)
Water Solubility Soluble in alcohol, chloroform, benzene, and acetone. Insoluble in water, ether, carbon, and tetrachloride.
Merck 14,442
BRN 1213676
InChIKey HSMNQINEKMPTIC-UHFFFAOYSA-N
CAS DataBase Reference 61-78-9(CAS DataBase Reference)
NCI Dictionary of Cancer Terms PAH
FDA UNII Y79XT83BJ9
EPA Substance Registry System P-Aminohippuric acid (61-78-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  37/39-26-36
WGK Germany  3
8-9-23
TSCA  Yes
HS Code  29242990
NFPA 704
1
0 1

4-Aminohippuric acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3174 Aminohippuric Acid pharmaceutical secondary standard, certified reference material 61-78-9 500MG $200 2024-03-01 Buy
Sigma-Aldrich 8.14621 4-Aminohippuric acid for synthesis 61-78-9 25g $191 2024-03-01 Buy
Sigma-Aldrich 08090 p-Aminohippuric acid ≥98.0% (T) 61-78-9 50g $387 2023-01-07 Buy
TCI Chemical A0313 4-Aminohippuric Acid >99.0%(T) 61-78-9 10g $171 2024-03-01 Buy
TCI Chemical A0313 4-Aminohippuric Acid >99.0%(T) 61-78-9 25g $342 2024-03-01 Buy
Product number Packaging Price Buy
PHR3174 500MG $200 Buy
8.14621 25g $191 Buy
08090 50g $387 Buy
A0313 10g $171 Buy
A0313 25g $342 Buy

4-Aminohippuric acid Chemical Properties,Uses,Production

Description

4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1; Km = 14.3 μM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1; Km = 2.66 mM in HEK293 cells), and apical multidrug resistance protein (MDR2; Km = 880 μM in HEK293 cells). 4-Aminohippuric acid is a glycine amide form of 4-aminobenzoic acid . Formulations containing 4-aminohippuric acid have been used as markers to determine renal plasma flow.

Chemical Properties

off-white to greyish crystalline powder

Uses

p-Aminohippuric acid has been used as infusions to measure plasma flow.

Uses

muscle relaxant (smooth)

Uses

4-Aminohippuric Acid is used in the measurement of renal plasma flow as a diagnostic tool which may be applied towards kidney disorders.

Definition

ChEBI: An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.

General Description

Renal tubules secretes para amino hippuric acid/PAH.

Biochem/physiol Actions

Para-aminohippuric acid?(PAH) is used as a marker in nutrition studies to measure the flow of blood in pigs, which inturn helps to determine the portal-drained viscera (PDV) flux of nutrients.

Purification Methods

Crystallise the acid from H2O. It is soluble in organic solvents. [Cohen & McGilvery J Biol Chem 169 119 1945, 171 121 1947, Meunzen et al. J Biol Chem 26 469 1926, Beilstein 14 III 1069, 14 IV 1152.]

4-Aminohippuric acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 253)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Gubang New Materail Technology Co. LTD
21-51317962 +8618721305404 16728589@qq.com CHINA 272 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58

Related articles

View Lastest Price from 4-Aminohippuric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINOHIPPURIC ACID pictures 2024-04-12 4-AMINOHIPPURIC ACID
61-78-9
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
4-AMINOHIPPURIC ACID pictures 2022-10-15 4-AMINOHIPPURIC ACID
61-78-9
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
4-AMINOHIPPURIC ACID pictures 2019-12-25 4-AMINOHIPPURIC ACID
61-78-9
US $0.10 / KG 1KG 95%-99% 1kg; 100kg; 1000kg Career Henan Chemical Co
|p|-AMinohippuric acid (PAH) 2-[(4-aminophenyl)carbonylamino]ethanoic acid 2-[[(4-aminophenyl)-oxomethyl]amino]acetic acid Aminohippuric acid [USAN] Hippuric acid, p-amino- Hippuric acid, p-amino- (8CI) Nefrotest N-[(4-aminophenyl)carbonyl]glycine p-Aminohippuric acid (PAH) 4-Aminohippuric acid(p-Aminohippuric acid) n-(4-aminobenzoyl)-glycin n-(para-aminobenzoyl)glycine pah(aminoacid) 4-Aminohippuric acid;PAH P-AMINOHIPPURIC ACID FREE ACID 4-Aminohippuricacid,97% Aminohippuric Glycine, N-(4-aminobenzoyl)- 2-[(4-aminobenzoyl)amino]acetic acid N-(4-AMINOBENZOYL)GLYCINE / 4-AMINOHIPPURIC ACID 4-AMINOHIPPURIC ACID BIOTECH 4-Aminohippuric acid, N-(4-Aminobenzoyl)glycine, p-Aminohippuric acid 4-Aminohippuric acid,99% N-glycine 4-AMINOHIPPURIC ACID FOR SYNTHESIS 2-(4-AMinobenzaMido)acetic acid Aminohippuric Acid (200 mg) paha p-amino-hippuricaci para-aminohippuricacid AKOS BBS-00006940 (4-AMINO-BENZOYLAMINO)-ACETIC ACID 4-AMINOBENZOYL GLYCINE 4-AMINOHIPPURIC ACID 2-[4-AMINOPHENYLCARBOXYAMINO]-ACETIC ACID LABOTEST-BB LT00053657 MIXTURE NO 6-POLYNUCLEAR AROMATIC HYDROCARBONS N-4-AMINOHIPPURIC ACID N-(4-AMINOBENZOYL)AMINOACETIC ACID N-(4-AMINOBENZOYL)GLYCINE N-(P-AMINOBENZOYL)-AMINOACETIC ACID N-[P-AMINOBENZOYL]GLYCINE P-AMINOBENZOYLGLYCINE TIMTEC-BB SBB000329 4-Aminohippuric Acid > 4-AMINOHIPPURIC ACID USP/EP/BP Aminohippuric Acid (1025351) POLYNUCLEAR AROMATIC HYDROCARBONS PAH P-AMINOHIPPURIC ACID 4-Aminohippuric Acid, ≥ 99.0% 61-78-9 H2NC6H4CONHCH2COOH H2NC6D4CONHCH2COOH NH2C6H4CONHCH2COOH AMINE Peptide Synthesis Modified Amino Acids