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TSH

TSH
TSH structure
CAS No.
9002-71-5
Chemical Name:
TSH
Synonyms
TSH;HTSH;BTSH;pretiron;thytropar;TSH HUMAN;TSH BOVINE;BOVINE TSH;dermathycin;THYROTROPIN
CBNumber:
CB5351862
Molecular Formula:
Formula Weight:
0
MOL File:
Mol file

TSH Properties

storage temp. 
2-8°C
form 
lyophilized powder
Merck 
13,9870
EWG's Food Scores
1
NCI Dictionary of Cancer Terms
thyroid-stimulating hormone; thyrotropin alfa; TSH
SAFETY
  • Risk and Safety Statements
Hazard Codes  B
WGK Germany  3
RTECS  XP3581600
10-21

TSH price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 869006-M Thyrotropic hormone from human pituitary 9002-71-5 10ug $239 2019-12-02 Buy
Sigma-Aldrich 869006-M Thyrotropic hormone from human pituitary 9002-71-5 50ug $512 2019-12-02 Buy
Sigma-Aldrich 869006-M Thyrotropic hormone from human pituitary 9002-71-5 100ug $855 2019-12-02 Buy
Sigma-Aldrich T8931 Thyrotropic hormone from bovine pituitary 9002-71-5 10vl $1280 2019-12-02 Buy
Sigma-Aldrich T9265 Thyrotropic hormone from human pituitary 9002-71-5 .1mg $1580 2019-12-02 Buy

TSH Chemical Properties,Uses,Production

Uses

Thyrogen (Genzyme).

Definition

A hormone secreted by the anterior lobe of the pituitary gland. It increases the rate of removal of iodine from the blood by the thyroid gland, synthesis of the thyroid hormone, and its release into the bloodstream. The thyrotropic hormone is a protein with a low molecular weight (about 10,000) that contains some carbohydrate.

Indications

TSH, or thyrotropin, is a glycosylated protein of two subunits,  and . TSH stimulates the thyroid gland to produce thyroid hormones. Deficiencies are treated by giving thyroxine itself rather than TSH, but TSH is available for diagnostic purposes to differentiate between pituitary and thyroid gland failure as causes of hypothyroidism.

brand name

Thyrotrophin is INN and BAN.

General Description

The thyrotropic hormone, also called thyrotropin and thyroidstimulatinghormone (TSH), is a glycoprotein consisting oftwo polypeptide chains. This hormone promotes productionof thyroid hormones by affecting the kinetics of the mechanismby which the thyroid concentrates iodide ions from thebloodstream, thereby promoting incorporation of the halogeninto the thyroid hormones and release of hormones by thethyroid.
TSH (Thyropar) appears to be a glycoprotein (relativemolecular mass [Mr] 26,000–30,000) containing glucosamine,galactosamine, mannose, and fucose, whose homogeneityis yet to be established. It is produced by thebasophil cells of the anterior lobe of the pituitary gland.TSH enters the circulation from the pituitary, presumablytraversing cell membranes in the process. After exogenousadministration, it is widely distributed and disappears veryrapidly from circulation. Some evidence suggests that thethyroid may directly inactivate some of the TSH by an oxidationmechanism that may involve iodine. TSH thus inactivatedcan be reactivated by certain reducing agents.TSH regulates the production by the thyroid gland of thyroxine,which stimulates the metabolic rate. Thyroxinefeedback mechanisms regulate the production of TSH bythe pituitary gland.

Veterinary Drugs and Treatments

The labeled indications for the formerly available veterinary product Dermathycin? (Mallinckrodt) was for “the treatment of acanthosis nigricans and for temporary supportive therapy in hypothyroidism in dogs.” In actuality however, TSH is used in veterinary medicine principally as a diagnostic agent in the TSH stimulation test to diagnose primary hypothyroidism.

TSH Preparation Products And Raw materials

Raw materials

Preparation Products


TSH Suppliers

Global( 36)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20039 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 20535 58
Beijing HuaMeiHuLiBiological Chemical 010-56205725
010-65763397 waley188@sohu.com China 12341 58
Sigma-Aldrich 800-8193336 021-61415566-
orderCN@merckgroup.com;orderCN@merckgroup.com China 34130 80

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