Imperatorin
- CAS No.
- 482-44-0
- Chemical Name:
- Imperatorin
- Synonyms
- AMMIDIN;Marmelide;MARMELOSIN;Pentosalen;NSC 402949;Imperatori;8-ISOAMYLEN;IMPERATORIN;AKOS 214-72;Enoxypsoralen
- CBNumber:
- CB5355754
- Molecular Formula:
- C16H14O4
- Molecular Weight:
- 270.28
- MDL Number:
- MFCD00016881
- MOL File:
- 482-44-0.mol
- MSDS File:
- SDS
| Melting point | 98-100°C |
|---|---|
| Boiling point | 333.4°C (rough estimate) |
| Density | 1.1311 (rough estimate) |
| refractive index | 1.4350 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO: ≥5mg/mL |
| form | powder |
| color | off-white to light brown |
| λmax | 301nm(MeOH)(lit.) |
| Merck | 14,4925 |
| InChIKey | OLOOJGVNMBJLLR-UHFFFAOYSA-N |
| LogP | 2.983 (est) |
| CAS DataBase Reference | 482-44-0(CAS DataBase Reference) |
| FDA UNII | K713N25C78 |
| NIST Chemistry Reference | 7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-(482-44-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1575000 | |||||||||
| HS Code | 29419090 | |||||||||
| NFPA 704 |
|
Imperatorin price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I6659 | Imperatorin ≥98% (HPLC), powder | 482-44-0 | 5mg | $148 | 2024-03-01 | Buy |
| TCI Chemical | I0904 | Imperatorin >98.0%(HPLC) | 482-44-0 | 25mg | $84 | 2024-03-01 | Buy |
| TCI Chemical | I0904 | Imperatorin >98.0%(HPLC) | 482-44-0 | 100mg | $228 | 2024-03-01 | Buy |
| Cayman Chemical | 26070 | Imperatorin ≥98% | 482-44-0 | 10mg | $74 | 2024-03-01 | Buy |
| Cayman Chemical | 26070 | Imperatorin ≥98% | 482-44-0 | 25mg | $111 | 2024-03-01 | Buy |
Imperatorin Chemical Properties,Uses,Production
Description
Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.
References
https://www.scbt.com/scbt/product/imperatorin-482-44-0
https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
https://en.wikipedia.org/wiki/Imperatorin
Chemical Properties
White Solid
Uses
Imperatorin (cas# 482-44-0) is a compound useful in organic synthesis.
Definition
ChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.
Imperatorin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
View Lastest Price from Imperatorin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Imperatorin
482-44-0
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2023-02-24 | Imperatorin
482-44-0
|
US $0.00 / mg | 5mg | Analytical Standard | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2022-02-14 | Imperatorin 482-44-0
482-44-0
|
US $15.00 / mg | 20mg | ≥98% | 1000.00 kgs | NanJing Spring & Autumn Biological Engineering CO., LTD. |
-
- Imperatorin
482-44-0
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Imperatorin
482-44-0
- US $0.00 / mg
- Analytical Standard
- Shanghai Standard Technology Co., Ltd.
-
- Imperatorin 482-44-0
482-44-0
- US $15.00 / mg
- ≥98%
- NanJing Spring & Autumn Biological Engineering CO., LTD.
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