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2'-Methoxycinnamaldehyde

2'-Methoxycinnamaldehyde Structure
2'-Methoxycinnamaldehyde structure
CAS No.
1504-74-1
Chemical Name:
2'-Methoxycinnamaldehyde
Synonyms
FEMA 3181;AKOS BBS-00003213;o-MethoxycinnamaL;3-(o-Anisyl)propenal;2-Methoxyciamaldehyde;O-Ethoxycinnamaldehyde;2′-Methoxycinnamaldehyd;2-methoxycimnamaldehyde;o-methoxy-cinnamaldehyd;2-METHOXYCINNAMALDEHYDE
CBNumber:
CB5356650
Molecular Formula:
C10H10O2
Molecular Weight:
162.19
MDL Number:
MFCD00007001
MOL File:
1504-74-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-22 18:57:36
Product description Number Pack Size Price
2-Methoxycinnamaldehyde natural, 98%, FG W318101 1 each $62.3
2-Methoxycinnamaldehyde natural, 98%, FG W318101 100g $88.7
2-Methoxycinnamaldehyde natural, 98%, FG W318101 1kg $227
2-Methoxycinnamaldehyde natural, 98%, FG W318101 10Kg $1700
2-Methoxycinnamaldehyde natural, 98%, FG W318101 25kg $3790
More product size
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2'-Methoxycinnamaldehyde Properties

Melting point 44-48 °C(lit.)
Boiling point 160-161 °C12 mm Hg(lit.)
Density 1.0281 (rough estimate)
refractive index 1.6000 (estimate)
FEMA 3181 | O-METHOXYCINNAMALDEHYDE
FLAVIS Number 05.048 | 2-Methoxycinnamaldehyde
Flash point >230 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Sparingly)
form Solid
color Yellow
Odor at 100.00 %. sweet cinnamon cassia oily woody paper
Odor Type spicy
biological source synthetic
JECFA Number 688
Cosmetics Ingredients Functions PERFUMING
ANTIOXIDANT
InChI 1S/C10H10O2/c1-12-10-7-3-2-5-9(10)6-4-8-11/h2-8H,1H3/b6-4+
InChIKey KKVZAVRSVHUSPL-GQCTYLIASA-N
SMILES COc1ccccc1\C=C\C=O
LogP 2.13
CAS DataBase Reference 1504-74-1(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) O-METHOXYCINNAMALDEHYDE
FDA 21 CFR 172.515
EWG's Food Scores 1
FDA UNII 4940G3R6HE
NIST Chemistry Reference 2-Propenal, 3-(2-methoxyphenyl)-(1504-74-1)
EPA Substance Registry System o-Methoxycinnamaldehyde (1504-74-1)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  2
RTECS  GD6590000
TSCA  TSCA listed
HS Code  29124990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

2'-Methoxycinnamaldehyde price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W318101 2-Methoxycinnamaldehyde natural, 98%, FG 1504-74-1 1 each $62.3 2026-03-19 Buy
Sigma-Aldrich W318101 2-Methoxycinnamaldehyde natural, 98%, FG 1504-74-1 100g $88.7 2026-03-19 Buy
Sigma-Aldrich W318101 2-Methoxycinnamaldehyde natural, 98%, FG 1504-74-1 1kg $227 2026-03-19 Buy
Sigma-Aldrich W318101 2-Methoxycinnamaldehyde natural, 98%, FG 1504-74-1 10Kg $1700 2026-03-19 Buy
Sigma-Aldrich W318101 2-Methoxycinnamaldehyde natural, 98%, FG 1504-74-1 25kg $3790 2026-03-19 Buy
Product number Packaging Price Buy
W318101 1 each $62.3 Buy
W318101 100g $88.7 Buy
W318101 1kg $227 Buy
W318101 10Kg $1700 Buy
W318101 25kg $3790 Buy

2'-Methoxycinnamaldehyde Chemical Properties,Uses,Production

Uses

o-Methoxycinnamaldehyde is a food flavoring permitted for use according to GB2760-1997.

Description

o-Methoxycinnamaldehyde has a sweet, warm, spicy-floral odor with fruity undertones. It has a sweet, spicy, warm flavor, somewhat pungent above 200 - 300 ppm. It is formed after a long contact period between salicylaldehyde and acetaldehyde in diluted alkaline solution; it can be formed by condensation of salicylaldehyde methylether with acetaldehyde under alkaline conditions; from the corresponding oxime.

Chemical Properties

o-Methoxycinnamaldehyde has a sweet, warm, spicy-floral odor with fruity undernotes. It has a sweet, spicy, warm flavor and is somewhat pungent above 200 to 300ppm.

Occurrence

Reported found in cinnamon oil (Cinnamomum cassia Nees ex Bl.) from which it is separated as stearoptene; in cinnamon bark and leaf.

Preparation

It is formed after a long contact period between salicylaldehyde and acetaldehyde in diluted alkaline solution; it may also be formed by condensation of salicylaldehyde methylether with acetaldehyde under alkaline conditions; from the corresponding oxime. It may be isolated and purified from powdered cinnamon.

Definition

ChEBI: Cassiastearoptene is a member of cinnamaldehydes.

Taste threshold values

Taste characteristics at 50 ppm: warm, spicy, cinnamon and clove-like.

General Description

Yellow crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Aldehydes, such as 2'-Methoxycinnamaldehyde, are frequently involved in self-condensation or polymerization reactions. These reactions are exothermic; they are often catalyzed by acid. Aldehydes are readily oxidized to give carboxylic acids. Flammable and/or toxic gases are generated by the combination of aldehydes with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Aldehydes can react with air to give first peroxo acids, and ultimately carboxylic acids. These autoxidation reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by the products of the reaction). The addition of stabilizers (antioxidants) to shipments of aldehydes retards autoxidation.

Fire Hazard

2'-Methoxycinnamaldehyde is flammable.

Synthesis

o-Methoxycinnamyl alcohol

1504-61-6

2'-Methoxycinnamaldehyde

1504-74-1

The general procedure for the synthesis of 2'-methoxycinnamaldehyde from the compound (CAS:1504-61-6) is as follows: alcohol (5.0 mmol), copper acetate (Cu(OAc)2, 9.1 mg, 0.05 mmol), and TEMPO (7.8 mg, 0.05 mmol) were mixed in a mixture of acetonitrile (CH3CN, 5 mL) and water (H2O, 10 mL) in a mixed solvents at room temperature with stirring for the indicated times. The progress of the reaction was monitored by thin-layer chromatography (TLC) with the eluent ratio of petroleum ether/ethyl acetate = 4/1. After completion of the reaction, the reaction mixture was extracted by adding dichloromethane (10 mL) to the reaction mixture. The organic phase was separated and the aqueous phase was extracted twice more with dichloromethane (10 mL x 2). All organic layers were combined, dried with anhydrous sodium sulfate and concentrated to obtain the crude product. The crude product was purified by column chromatography with the eluent ratio of petroleum ether/ethyl acetate=10/1, and the target product 2'-methoxycinnamaldehyde was finally obtained.

target

P450 (e.g. CYP17)

References

[1] Tetrahedron Letters, 2014, vol. 55, # 10, p. 1677 - 1681
[2] European Journal of Organic Chemistry, 2016, vol. 2016, # 20, p. 3401 - 3407
[3] Bioorganic and Medicinal Chemistry Letters, 1997, vol. 7, # 19, p. 2473 - 2476

2'-Methoxycinnamaldehyde synthesis

1504-61-6
1504-74-1
Synthesis of 2'-Methoxycinnamaldehyde from o-Methoxycinnamyl alcohol

2'-Methoxycinnamaldehyde Preparation Products And Raw materials

Raw materials

o-Methoxycinnamyl alcohol TEMPO Acetonitrile Water Copper(II) acetate

Preparation Products

3-(2-METHOXY-PHENYL)-PROPIONALDEHYDE o-Methoxycinnamyl alcohol

2'-Methoxycinnamaldehyde Suppliers

Global( 237)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29821 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10000 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 9546 58
SIMAGCHEM CORP 		+86-5922680277 +86-13806087780 sale@simagchem.com China 17346 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
career henan chemical co 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
Shanghai Standard Technology Co., Ltd. 		58
Alchem Pharmtech,Inc. 		58
Fuxin Pharmaceutical 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
SIMAGCHEM CORP 		58

View Lastest Price from 2'-Methoxycinnamaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-methoxycinnamaldehyde pictures 2026-04-22 2-methoxycinnamaldehyde
1504-74-1
 US $39.00 / mL 98.00% 10g TargetMol Chemicals Inc.
2'-Methoxycinnamaldehyde pictures 2026-03-20 2'-Methoxycinnamaldehyde
1504-74-1
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2′-Methoxycinnamaldehyde pictures 2025-05-26 2′-Methoxycinnamaldehyde
1504-74-1
 US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD

2'-Methoxycinnamaldehyde Spectrum

2'-Methoxycinnamaldehyde(1504-74-1)1HNMR2'-Methoxycinnamaldehyde(1504-74-1)IR

1504-74-1(2'-Methoxycinnamaldehyde)Related Search:

Anisole Octyl 4-methoxycinnamate Cinnamaldehyde p-Anisidine 2-Methoxypropene
(Trifluoromethoxy)benzene Guaiacol trans-Cinnamaldehyde 4-(Dimethylamino)cinnamaldehyde 2-PROPENAL, 3-(4-METHYLPHENYL)-,(2E)
α-Methylcinnamaldehyde Acrolein AFLATOXIN G1 Coumarin-3-carboxylic acid 2,4-DIMETHOXYCINNAMIC ACID
trans-2,3,4-Trimethoxycinnamic acid trans-2,4,5-Trimethoxycinnamic acid trans-2,3-Dimethoxycinnamic acid

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(2E)-3-(2-Methoxyphenyl)-2-propenal 2-methoxycimnamaldehyde 2-Methoxycinnamic aldehyde 2-METHOXYCINNAMALDEHYDE 99+% (2E)-3-(2-Methoxyphenyl)acrylaldehyde O-METHOXYCINNAMALDEHYDE 96+% ORTHO-METHOXYCINNAMALDEHYDE 2′-Methoxycinnamaldehyd METHYLCUMARALDEHYD-ORTHO O-METHOXY CINNAMIC ALDEHYDE MIXTURE IN CINNAMIC ALDEHYDE O-METHOXY CINNAMIC ALDEHYDE, NATURAL ortho-METHOXY CINNAMIC ALDEHYDE, FUSED 2-Methoxybenzeneacrylaldehyde 2-Methoxybenzenepropenal 3-(2-Methoxyphenyl)propenal 3-(o-Anisyl)propenal (E)-2-Methoxycinnamaldehyde 2-Methoxy-trans-cinnamaldehyde O-Ethoxycinnamaldehyde 2-Methoxyciamaldehyde 3-(2-Methoxyphenyl)acrylaldehyde 2-MethoxycinnaMaldehyde, predoMinantly trans 96% beta-(o-Methoxyphenyl)acrolein Cinnamaldehyde, o-methoxy- o-methoxy-cinnamaldehyd 2-PROPENYL-3(2-METHOXYPHENOL) 2-METHOXYCINNAMALDEHYDE 2-propenal,3-(2-methoxyphenyl)- 3-(2-methoxyphenyl)-2-propena 3-(2-methoxyphenyl)-2-Propenal ORTHO-METHOXY CINNAMIC ALDEHYDE O-METHOXYCINNAMALDEHYDE O-METHOXY CINNAMIC ALDEHYDE AKOS BBS-00003213 FEMA 3181 0-Methoxy Cinnamaldehyde (E)-3-(2-methoxyphenyl)-2-propenal o-MethoxycinnamaL 2'-Methoxycinnamaldehyde USP/EP/BP o-Methoxy Cinnamic Aldehyde Nat 2'-Methoxycinnamaldehyde 2-methoxycinnamaldehyde, 10 mM in DMSO 2-Methoxycinnamaldehyde, predominantly trans o-Methoxycinnamaldehyde 1504-74-1 Organic Building Blocks Aldehydes Building Blocks C10 to C21 Carbonyl Compounds Aldehydes Building Blocks C10-C12 Carbonyl Compounds Chemical Synthesis Nutrition Research Ocimum basilicum (Basil) Organic Building Blocks