ChemicalBook >> CAS DataBase List >>3,6-DIOXA-1,8-OCTANEDITHIOL

3,6-DIOXA-1,8-OCTANEDITHIOL

CAS No.
14970-87-7
Chemical Name:
3,6-DIOXA-1,8-OCTANEDITHIOL
Synonyms
1,8-DIMERCAPTO-3,6-DIOXAOCTANE;2,2’-(ethylenedioxy)diethanethiol;SH-PEG2-SH;Triglycoldimercaptan;3,6-dioxa-1,8-octandithiol;3,6-dioxy-1,8-octyldithiol;3,6-DIOXA-1,8-OCTANEDITHIOL;3,6-Dioxa-1,8-OCLanedithiol;Triethyleneglycol dimrcaptan;3,6-Dioxa-1,8-octanebisthiol
CBNumber:
CB5379455
Molecular Formula:
C6H14O2S2
Molecular Weight:
182.3
MDL Number:
MFCD00015873
MOL File:
14970-87-7.mol
MSDS File:
SDS
Last updated:2023-12-25 17:47:29

3,6-DIOXA-1,8-OCTANEDITHIOL Properties

Boiling point 225 °C(lit.)
Density 1.12 g/mL at 25 °C(lit.)
vapor pressure 0.39Pa at 20℃
refractive index n20/D 1.509(lit.)
Flash point 132 °C
solubility Slightly soluble in water
form clear liquid
pka 9.34±0.10(Predicted)
color Colorless to Light yellow to Light orange
Water Solubility 11.4g/L at 19.8℃
BRN 1901671
LogP 1.6 at 55℃
CAS DataBase Reference 14970-87-7(CAS DataBase Reference)
FDA UNII 83CA1M23NC
EPA Substance Registry System Ethanethiol, 2,2'-[1,2-ethanediylbis(oxy)]bis- (14970-87-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H332-H410
Precautionary statements  P261-P264-P270-P273-P301+P310-P304+P340+P312
Hazard Codes  T,N,Xn
Risk Statements  22-23-36/37/38-51/53-20/22
Safety Statements  26-45-61
RIDADR  UN 2810 6.1/PG 3
WGK Germany  2
HS Code  29309090
NFPA 704
1
3 0

3,6-DIOXA-1,8-OCTANEDITHIOL price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 465178 2,2′-(Ethylenedioxy)diethanethiol 95% 14970-87-7 100ml $46.4 2024-03-01 Buy
Sigma-Aldrich 465178 2,2′-(Ethylenedioxy)diethanethiol 95% 14970-87-7 500ml $137.6 2024-03-01 Buy
TCI Chemical D2649 3,6-Dioxa-1,8-octanedithiol >97.0%(GC)(T) 14970-87-7 25g $23 2024-03-01 Buy
TCI Chemical D2649 3,6-Dioxa-1,8-octanedithiol >97.0%(GC)(T) 14970-87-7 100g $66 2024-03-01 Buy
TCI Chemical D2649 3,6-Dioxa-1,8-octanedithiol >97.0%(GC)(T) 14970-87-7 500g $198 2024-03-01 Buy
Product number Packaging Price Buy
465178 100ml $46.4 Buy
465178 500ml $137.6 Buy
D2649 25g $23 Buy
D2649 100g $66 Buy
D2649 500g $198 Buy

3,6-DIOXA-1,8-OCTANEDITHIOL Chemical Properties,Uses,Production

Uses

3,6-dioxa-1,8-octanedithiol (DODT) was used for cleaving peptides in the study to develop synthetic peptide serology to treat chronic chagas disease. DODT may be used to develop non-malodorous scavenger in Fmoc-based peptide synthesis.

Definition

3,6-dioxa-1,8-octanedithiol is a dithiol monomer. This compound could be chosen as a model compound for the active sites of thioredoxins to study its reactions with cis-[Pt(NH3)2Cl4] and trans-[PtCl2(CN)4]2– (cisplatin prodrug and a model complex). The pKa values for the dithiol were characterized to be 8.7 ± 0.2 and 9.6 ± 0.2 at 25.0 °C and an ionic strength of 1.0 M. Triethylamine (TEA) and dilute H2O2 could catalyze the new Radical Ring-opening Redox Polymerization (R3P) of 3,6-dioxa-1,8-octanedithiol[1-2].

Synthesis Reference(s)

The Journal of Organic Chemistry, 33, p. 1275, 1968 DOI: 10.1021/jo01267a089
Triglycol dimercaptan

General Description

3,6-dioxa-1,8-octanedithiol is non volatile in nature.

References

[1] DONGYING MA. Formation of peptide disulfide bonds through a trans-dibromido-Pt(IV) complex oxidation reaction: Kinetic and mechanistic analyses[J]. Journal of Molecular Liquids, 2021. DOI:10.1016/j.molliq.2020.115195.
[2] ROSENTHAL-KIMEMILY Q PuskasJudit E. Green polymer chemistry: investigating the mechanism of radical ring-opening redox polymerization (R3P) of 3,6-dioxa-1,8-octanedithiol (DODT).[J]. Molecules, 2015. DOI:10.3390/molecules20046504.

19249-03-7
14970-87-7
Synthesis of 3,6-DIOXA-1,8-OCTANEDITHIOL from Tri(Ethylene Glycol) DI-P-Toluenesulfonate

3,6-DIOXA-1,8-OCTANEDITHIOL Preparation Products And Raw materials

Global( 144)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Gubang New Materail Technology Co. LTD
21-51317962 +8618721305404 16728589@qq.com CHINA 272 58
Zhengzhou Anhuida Chemical Co., Ltd
+8615903659408 admin@ahdchem.com China 298 58
Hebei Guanlang Biotechnology Co,.LTD
+8619930503252 daisy@crovellbio.com China 5966 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14764 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Richest Group Ltd
18017061086 oled@richest-group.com CHINA 5601 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58

View Lastest Price from 3,6-DIOXA-1,8-OCTANEDITHIOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,6-DIOXA-1,8-OCTANEDITHIOL pictures 2023-12-26 3,6-DIOXA-1,8-OCTANEDITHIOL
14970-87-7
US $0.00 / kg 1kg 99% 10000 Hebei Jingbo New Material Technology Co., Ltd
2,2 -(Ethylenedioxy)diethanethiol  pictures 2023-08-15 2,2 -(Ethylenedioxy)diethanethiol
14970-87-7
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
3,6-DIOXA-1,8-OCTANEDITHIOL pictures 2022-08-06 3,6-DIOXA-1,8-OCTANEDITHIOL
14970-87-7
US $180.00-1500.00 / kg 1kg 98% 5000kg Zhengzhou Anhuida Chemical Co., Ltd
Triglycoldimercaptan ETHYLENE GLYCOL BIS(2-MERCAPTOETHYL) ETHER 1,2-BIS(2-MERCAPTOETHOXY)ETHANE 3,6-DIOXA-1,8-OCTANEDITHIOL Triethyleneglycol dimrcaptan Ethanethiol, 2,2-1,2-ethanediylbis(oxy)bis- 2,2′-[1,2-Ethandiylbis(oxy)]bis(ethanthiol) 2,2'-[1,2-ethanediylbis(oxy)]bis-Ethanethiol Triglycol dimercaptan 2,2'-[1,2-ethanediylbis(oxy)]bis-ethanethio 2,2'-(ethylenedioxy)diethanethiol Triethyleneglycol dimercaptan 1,2-Bis(2-mercaptoethoxy)ethane, 3,6-Dioxa-1,8-octane-dithiol 2,2'-(Ethylenebisoxy)bisethanethiol 2,2'-Ethylenebis(oxy)bis(ethanethiol) 3,6-Dioxa-1,8-octanebisthiol 1,2-Bis(2-mercaptoethoxy)ethane 1,8-Dimercapto-3,6-dioxaoctane Ethylene Glycol Bis(2-mercaptoethyl) Ether 3,6-Dioxa-1,8-OCLanedithiol 2,2’-[1,2-ethanediylbis(oxy)]bis-ethanethio 2,2’-[1,2-ethanediylbis(oxy)]bis-Ethanethiol 2,2'-(ethane-1,2-diylbis(oxy))diethanethiol 2,2'-(Ethylenedioxy)diethanethiol 95% 3,6-dioxa-1,8-octandithiol 3,6-Dioxa-1,8-octanedithiol > 2-[2-(2-sulfanylethoxy)ethoxy]ethanethiol 2,2′-(Ethylenedioxy)diethanethiol (DMDO) 1,8-DIMERCAPTO-3,6-DIOXAOCTANE 2,2’-(ethylenedioxy)diethanethiol SH-PEG2-SH 3,6-Dioxa-1,8-Octanedithiol CAS NO.14970-87-7 3,6-dioxy-1,8-octyldithiol 14970-87-7 HSCH2CH2OCH2CH2OCH2CH2SH C2H14O2S2 peg