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SIB 1893

SIB 1893 Structure
SIB 1893 structure
CAS No.
6266-99-5
Chemical Name:
SIB 1893
Synonyms
SIB 1893;NSC 36665;(E/Z)-SIB-1893;(E/Z)SIB1893,(E/Z) SIB 1893;(E)-2-METHYL-6-STYRYL-PYRIDINE;2-METHYL-6-(2-PHENYLETHENYL)PYRIDINE;(E)-2-METHYL-6-(2-PHENYLETHYL)-PYRIDINE;Pyridine, 2-methyl-6-(2-phenylethenyl)-;2-Methyl-6-[(E)-2-phenylethenyl]pyridine
CBNumber:
CB5393055
Molecular Formula:
C14H13N
Molecular Weight:
195.26
MDL Number:
MFCD02262120
MOL File:
6266-99-5.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19
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SIB 1893 Properties

storage temp. 2-8°C
solubility DMSO: 18 mg/mL
form solid
FDA UNII 4X2F5X24UK

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

SIB 1893 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 1214 SIB 1893 6266-99-5 10 $118 2021-12-16 Buy
Tocris 1214 SIB 1893 6266-99-5 50 $495 2021-12-16 Buy
TRC S411003 SIB 1893 6266-99-5 10mg $80 2021-12-16 Buy
Usbiological 256664 SIB 1893 6266-99-5 10mg $389 2021-12-16 Buy
ApexBio Technology B6635 SIB 1893 6266-99-5 10mg $228 2021-12-16 Buy
Product number Packaging Price Buy
1214 10 $118 Buy
1214 50 $495 Buy
S411003 10mg $80 Buy
256664 10mg $389 Buy
B6635 10mg $228 Buy

SIB 1893 Chemical Properties,Uses,Production

Uses

SIB 1893 is a selective antagonist of mGluR-5. SIB 1893 acts as a positive allosteric modulator of human metabotropic mGlu4 (1). Anticonvulsant (2).

Definition

ChEBI: 2-methyl-6-(2-phenylethenyl)pyridine is a member of styrenes.

Biological Activity

A highly selective non-competitive antagonist for the metabotropic glutamate mGlu 5 receptor subtype; displays an IC 50 value of 0.3 μ M? at hmGlu 5 , compared with > 100 μ M at hmGlu 1b , hmGlu 2 , hmGlu 6 , hmGlu 7 and hmGlu 8 . Centrally active upon systemic administration in vivo . Positive allosteric modulator at mGlu 4 receptors.

SIB 1893 Preparation Products And Raw materials

Raw materials

Preparation Products

SIB 1893 Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Hangzhou Yuhao Chemical Technology Co., Ltd 0571-82693216 info@yuhaochemical.com China 9394 52
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 2031 58
AdooQ Bioscience CHINA 025-58849295 18951903616; info@adooq.cn China 2989 60
BOC Sciences -- info@bocsci.com USA 0 65
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Hangzhou Yuhao Chemical Technology Co., Ltd 52
HangZhou YuHao Chemical Technology Co., Ltd. 58
AdooQ Bioscience CHINA 60
BOC Sciences 65

6266-99-5(SIB 1893)Related Search:

ETHYLENE stilbazium iodide SIB 1893 4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(3-NITROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-(4-METHOXYSTYRYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(3-BROMOPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(2-CHLOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 2-[(E)-2-(4-FLUOROPHENYL)ETHENYL]-5-OXO-4-(3,4,5-TRIMETHOXYPHENYL)-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(3-CHLOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-(3,4-DICHLOROSTYRYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(4-FLUOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(4-CHLOROPHENYL)ETHENYL]-5H-INDENO[1,2-B]PYRIDIN-5-ONE 4-(2-FLUOROPHENYL)-2-[(E)-2-(3-METHOXYPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 2-[(E)-2-(3-CHLOROPHENYL)ETHENYL]-4-(4-HEPTYLPHENYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-[(E)-2-(2-FLUOROPHENYL)ETHENYL]-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE
4-(1,3-BENZODIOXOL-5-YL)-2-(4-HYDROXYSTYRYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE 4-(1,3-BENZODIOXOL-5-YL)-2-(4-NITROSTYRYL)-5-OXO-5H-INDENO[1,2-B]PYRIDINE-3-CARBONITRILE

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SIB 1893 2-METHYL-6-(2-PHENYLETHENYL)PYRIDINE (E)-2-METHYL-6-(2-PHENYLETHYL)-PYRIDINE (E)-2-METHYL-6-STYRYL-PYRIDINE 2-Methyl-6-[(E)-2-phenylethenyl]pyridine NSC 36665 Pyridine, 2-methyl-6-(2-phenylethenyl)- (E/Z)-SIB-1893 (E/Z)SIB1893,(E/Z) SIB 1893 6266-99-5 Glutamate receptor