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S- (+)-Rolipram

S- (+)-Rolipram structure

CAS No.: 85416-73-5

Chemical Name:: S- (+)-Rolipram

Synonyms: (+)-Rolipram;(S)-(+)-ROLIPRAM;Rolipram (S)-(+)-;S- (+)-Rolipram (ME-3167;(+)-ROLIPRAM;(S)-ROLIPRAM;S- (+)-Rolipram USP/EP/BP;Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

CBNumber:: CB5397417

Molecular Formula:: C16H21NO3

Molecular Weight:: 275.34

MDL Number:: MFCD03093861

MOL File:: 85416-73-5.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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S- (+)-Rolipram Properties

Melting point	133-136℃
Density	1.155
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form	White to off-white solid.
color	White to Almost white
FDA UNII	H6G4VMQ24K

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
HS Code	2933.79.1500

S- (+)-Rolipram price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	R0183	(S)-(+)-Rolipram >98.0%(HPLC)	85416-73-5	10mg	$178	2024-03-01	Buy
TCI Chemical	R0183	(S)-(+)-Rolipram >98.0%(HPLC)	85416-73-5	50mg	$622	2024-03-01	Buy
TRC	R640045	S-(+)-Rolipram	85416-73-5	10mg	$200	2021-12-16	Buy
ApexBio Technology	A4349	S-(+)-Rolipram	85416-73-5	25mg	$190	2021-12-16	Buy
AK Scientific	X5034	S-(+)-Rolipram	85416-73-5	50mg	$232	2021-12-16	Buy

Product number	Packaging	Price	Buy
R0183	10mg	$178	Buy
R0183	50mg	$622	Buy
R640045	10mg	$200	Buy
A4349	25mg	$190	Buy
X5034	50mg	$232	Buy

S- (+)-Rolipram Chemical Properties,Uses,Production

Uses

S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor

Uses

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer

Definition

ChEBI: The (S)-enantiomer of rolipram.

Biological Activity

Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).

storage

Room temperature

S- (+)-Rolipram synthesis

Synthesis of S- (+)-Rolipram from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

S- (+)-Rolipram Preparation Products And Raw materials

Raw materials

3-CYCLOPENTYLOXY-4-METHOXYBENZALDEHYDE Bromocyclopentane Isovanillin

Preparation Products

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

S- (+)-Rolipram Suppliers

Global( 85)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	3581	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21149	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29220	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58

Supplier	Advantage
Hubei xin bonus chemical co. LTD	58
career henan chemical co	58
Shaanxi Dideu Medichem Co. Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Alfa Chemistry	58
InvivoChem	58
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58

View Lastest Price from S- (+)-Rolipram manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-07-20	S- (+)-Rolipram 85416-73-5	US $0.00-0.00 / KG	5mg	99% HPLC	2000tons	Shaanxi Dideu Medichem Co. Ltd
	2020-03-16	S- (+)-Rolipram 85416-73-5	US $1.00 / KG	1KG	97%-99.9%	100KG	Career Henan Chemical Co

S- (+)-Rolipram
85416-73-5
US $0.00-0.00 / KG
99% HPLC
Shaanxi Dideu Medichem Co. Ltd

S- (+)-Rolipram
85416-73-5
US $1.00 / KG
97%-99.9%
Career Henan Chemical Co

S- (+)-Rolipram Spectrum

S- (+)-Rolipram(85416-73-5)¹HNMR

85416-73-5(S- (+)-Rolipram)Related Search:

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AG 1295 (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE EHNA HYDROCHLORIDE S- (+)-Rolipram

4-(3'-Methoxyphenyl)-2-pyrrolidinone 4-(4'-Methoxyphenyl)-2-pyrrolidinone 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

1of4

(S)-(+)-ROLIPRAM (4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one Rolipram (S)-(+)- (4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE (4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone (S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone (4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone (+)-ROLIPRAM;(S)-ROLIPRAM 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4S)- (S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one S- (+)-Rolipram USP/EP/BP S- (+)-Rolipram (ME-3167 (+)-Rolipram TNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Rolipram,Phosphodiesterase (PDE),cAMP,Inhibitor,factor,necrosis Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4） 85416-73-5 Signalling Cyclic Nucleotide related Inhibitors