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ChemicalBook >> CAS DataBase List >>5,6BETA-DIHYDRO PGI2

5,6BETA-DIHYDRO PGI2

5,6BETA-DIHYDRO PGI2 Structure
5,6BETA-DIHYDRO PGI2 structure
CAS No.
62770-50-7
Chemical Name:
5,6BETA-DIHYDRO PGI2
Synonyms
6β-Prostaglandin I1;5,6BETA-DIHYDRO PGI2;6BETA-PROSTAGLANDIN I1;5,6-dihydroprostacyclin;RJADQDXZYFCVHV-CBIPHORWSA-N;6S,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;(6S,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6S,9α,11α,13E,15S)- (9CI)
CBNumber:
CB5405420
Molecular Formula:
C20H34O5
Molecular Weight:
354.48
MDL Number:
MFCD00135257
MOL File:
62770-50-7.mol
Last updated:2023-05-21 10:59:17
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5,6BETA-DIHYDRO PGI2 Properties

storage temp. Store at -20°C
solubility DMF: >10 mg/ml; DMSO: >5 mg/ml; Ethanol: >20 mg/ml; PBS pH 7.2: >80 μg/ml
form A crystalline solid

5,6BETA-DIHYDRO PGI2 price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18120 6β-Prostaglandin I1 ≥99% 62770-50-7 1mg $64 2024-03-01 Buy
Cayman Chemical 18120 6β-Prostaglandin I1 ≥99% 62770-50-7 5mg $280 2024-03-01 Buy
Cayman Chemical 18120 6β-Prostaglandin I1 ≥99% 62770-50-7 10mg $497 2024-03-01 Buy
AK Scientific 1439AH 5,6beta-DihydroPGI2 62770-50-7 1mg $168 2021-12-16 Buy
AHH MT-09763 5,6Beta-DihydroPGI2 99% 62770-50-7 0.01g $328 2021-12-16 Buy
Product number Packaging Price Buy
18120 1mg $64 Buy
18120 5mg $280 Buy
18120 10mg $497 Buy
1439AH 1mg $168 Buy
MT-09763 0.01g $328 Buy

5,6BETA-DIHYDRO PGI2 Chemical Properties,Uses,Production

Description

6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.1,2

Definition

ChEBI: 6-Prostaglandin I1 is a prostanoid.

References

1. Whittle, B.J.R., Moncada, S., Whiting, F., et al. Carbacyclin — a potent stable prostacyclin analogue for the inhibition of platelet aggregation Prostaglandins 19(4),605-627(1980).
2. Blair, I.A., Hensby, C.N., and MacDermot, J. Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: Prostanoid structure-activity relationships Br. J. Pharmac. 69(3),519-525(1980).

5,6BETA-DIHYDRO PGI2 Preparation Products And Raw materials

Raw materials

Preparation Products

5,6BETA-DIHYDRO PGI2 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

62770-50-7(5,6BETA-DIHYDRO PGI2)Related Search:

11-DEOXY PROSTAGLANDIN F1ALPHA 5,6BETA-DIHYDRO PGI2 PROSTAGLANDIN F1ALPHA 1,9ALPHA,11ALPHA,15S-TETRAHYDROXY-PROST-13E-ENE
6BETA-PROSTAGLANDIN I1 6S,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID 5,6BETA-DIHYDRO PGI2 5,6-dihydroprostacyclin (6S,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid RJADQDXZYFCVHV-CBIPHORWSA-N Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6S,9α,11α,13E,15S)- (9CI) 6β-Prostaglandin I1 62770-50-7