Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID Structure
3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID structure
CAS No.
174603-55-5
Chemical Name:
3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID
Synonyms
Benzenepropanoic acid, 2-broMo-4-fluoro-;3-(2-broMo-4-fluorophenyl)propanoic acid;3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID
CBNumber:
CB5407611
Molecular Formula:
C9H8BrFO2
Molecular Weight:
247.06
MDL Number:
MFCD06656907
MOL File:
174603-55-5.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
Request For Quotation

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID Properties

Boiling point 331.4±27.0 °C(Predicted)
Density 1.606±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 4.59±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific W3815 3-(2-Bromo-4-fluorophenyl)propionicacid 174603-55-5 2.5g $1602 2021-12-16 Buy
American Custom Chemicals Corporation HCH0049569 3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID 95.00% 174603-55-5 5G $1784.48 2021-12-16 Buy
AK Scientific W3815 3-(2-Bromo-4-fluorophenyl)propionicacid 174603-55-5 10g $3357 2021-12-16 Buy
AccelPharmtech M1060 3-(2-bromo-4-fluorophenyl)propanoicacid 95.00% 174603-55-5 10G $1910 2021-12-16 Buy
Ambeed A162701 3-(2-Bromo-4-fluorophenyl)propionicacid 97% 174603-55-5 100mg $51 2021-12-16 Buy
Product number Packaging Price Buy
W3815 2.5g $1602 Buy
HCH0049569 5G $1784.48 Buy
W3815 10g $3357 Buy
M1060 10G $1910 Buy
A162701 100mg $51 Buy

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID Chemical Properties,Uses,Production

Synthesis

Propanedioic acid, 2-[(2-bromo-4-fluorophenyl)methyl]-, 1,3-diethyl ester

174603-54-4

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID

174603-55-5

Diethyl 2-(2-bromo-4-fluorobenzyl)-malonate (2.1 g, 6.07 mmol) was used as a raw material, which was mixed with water (14 mL) and potassium hydroxide (0.68 g, 12.14 mmol) was added. The reaction mixture was heated under reflux conditions for 4.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and ethanol was removed by distillation under reduced pressure. The aqueous residue was cooled to 100°C, acidified with concentrated sulfuric acid and subsequently heated at 120°C for 16 hours. After the reaction mixture was cooled to 0°C, the precipitated solid was collected by filtration, washed with water and dried to afford 3-(2-bromo-4-fluorophenyl)propionic acid as an off-white solid (0.5 g, 33% yield). Thin layer chromatography (TLC) showed an Rf value of 0.2 (unfolding agent: 30% ethyl acetate/petroleum ether).1H NMR (400 MHz, DMSO-d6) data were as follows: δ 12.26 (s, 1H), 7.55-7.52 (m, 1H), 7.42-7.38 (m, 1H), 7.23-7.18 (m, 1H), 2.90 (t. J = 7.8 Hz, 2H), 2.52 (t, J = 7.8 Hz, 2H).

References

[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 3, p. 409 - 416
[2] Patent: WO2015/36759, 2015, A1. Location in patent: Page/Page column 171

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID Preparation Products And Raw materials

Raw materials

Propanedioic acid, 2-[(2-bromo-4-fluorophenyl)methyl]-, 1,3-diethyl ester

Preparation Products

4-BROMO-6-FLUOROINDAN-1-ONE

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 12908 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49983 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Supplier Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58
Amadis Chemical Company Limited 		58

View Lastest Price from 3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(2-Bromo-4-fluorophenyl)propionic acid pictures 2020-02-01 3-(2-Bromo-4-fluorophenyl)propionic acid
174603-55-5
 US $1.00 / KG 1KG Min98% HPLC g/kg/ton Career Henan Chemical Co

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID Spectrum

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID(174603-55-5)1HNMR

174603-55-5(3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID)Related Search:

METHYL (2R)-2-AMINO-3-(2-BROMO-4-FLUOROPHENYL)PROPANOATE 2-amino-3-(2-bromo-4-fluorophenyl)propanoic acid METHYL (2S)-2-AMINO-3-(2-BROMO-4-FLUOROPHENYL)PROPANOATE RARECHEM AL BL 1062 METHYL (3R)-3-AMINO-3-(2-BROMO-4-FLUOROPHENYL)PROPANOATE
3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID ETHYL 3-AMINO-3-(2-BROMO-4-FLUOROPHENYL)PROPANOATE HYDROCHLORIDE 3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID ETHYL ESTER METHYL (3S)-3-AMINO-3-(2-BROMO-4-FLUOROPHENYL)PROPANOATE

1of2

3-(2-BROMO-4-FLUORO-PHENYL)-PROPIONIC ACID 3-(2-broMo-4-fluorophenyl)propanoic acid Benzenepropanoic acid, 2-broMo-4-fluoro- 174603-55-5