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FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH

FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH structure

CAS No.: 141743-15-9

Chemical Name:: FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH

Synonyms: FMOC-AEG-OH;FMOC-AEG(BOC)-OH;FMOC-BOCNHETGLY-OH;Fmoc-N-(2-Boc-aminoethyl)-Gly-OH;FMOC-N-(2-BOC-AMINOETHYL)-GLYCINE;Fmoc-N-(N-a-Boc-aminoethyl)-Gly-OH;Fmoc-N-(N-β-Boc-aminoethyl)-Gly-OH;FMoc-N-(N-b-Boc-aMinoethyl)-Gly-OH;FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH;FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLYCINE

CBNumber:: CB5428715

Molecular Formula:: C24H28N2O6

Molecular Weight:: 440.49

MDL Number:: MFCD02259490

MOL File:: 141743-15-9.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:42

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FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH Properties

Boiling point	638.3±48.0 °C(Predicted)
Density	1.250±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	3.85±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS09
Signal word	Warning
Hazard statements	H410
Precautionary statements	P273-P501
Hazard Codes	N
Risk Statements	50/53
Safety Statements	60-61
RIDADR	UN 3077 9/PG 3
WGK Germany	3
HS Code	29242990

FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	F604393	Fmoc-N-(2-Boc-aminoethyl)-Gly-OH	141743-15-9	500mg	$285	2021-12-16	Buy
Iris Biotech GmbH	FAA1767	Fmoc-Aeg(Boc)-OH	141743-15-9	1g	$168.75	2021-12-16	Buy
Activate Scientific	AS86257	Fmoc-N-(2-Boc-aminoethyl)glycine 95+%	141743-15-9	5G	$774	2021-12-16	Buy
American Custom Chemicals Corporation	AAA0003858	FMOC-N-(2-BOC-AMINOETHYL)-GLY-OH 95.00%	141743-15-9	1G	$848.93	2021-12-16	Buy
Chem-Impex	11190	Fmoc-N-(2-Boc-aminoethyl)glycine,99%(HPLC) 99%(HPLC)	141743-15-9	5G	$1310.4	2021-12-16	Buy

Product number	Packaging	Price	Buy
F604393	500mg	$285	Buy
FAA1767	1g	$168.75	Buy
AS86257	5G	$774	Buy
AAA0003858	1G	$848.93	Buy
11190	5G	$1310.4	Buy

FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

Fmoc-N-(2-Boc-aminoethyl)-Gly-OH is a Fmoc-protected glycine derivative that can be used in antibody agent coupling (ADC) synthesis. ADC consists of antibodies that are linked to ADC cytotoxins via ADC junctions[1].

Synthesis

N-(9-Fluorenylmethoxycarbonyloxy)succinimide

82911-69-1

2-[N-[2-(BOC-AMINO)ETHYL]AMINO]ACETIC ACID

90495-99-1

141743-15-9

The general procedure for the synthesis of Fmoc-N-(2-Boc-aminoethyl)glycine from 9-fluorenylmethyl-N-succinimidyl carbonate and 2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)acetic acid was as follows: 10.9 g (50 mmol) of 2-((2-((tert-butoxycarbonyl)amino)ethyl)amino)acetic acid was mixed and stirred with 50 mL of water, adding 11.3 g (135 mmol) sodium bicarbonate and 50 mL of tetrahydrofuran. Subsequently, 24.3 g (72 mmol) of 9-fluorenylmethyl-N-succinimidyl carbonate was added. The reaction mixture was stirred at room temperature for 20 h. After completion of the reaction, the resulting salt was removed by filtration. The filtrate was acidified to separate the phases and the organic phase was subsequently concentrated to afford the product N-(2-tert-butoxycarbonylaminoethyl)-N-(9-fluorenylmethoxycarbonyl)aminoacetic acid in 21.0 g (99%) yield.

References

[1] Hiroyuki Naito, et al. (anti-her2 antibody)-drug conjugate. EP3130608

FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH Preparation Products And Raw materials

Raw materials

N-(9-Fluorenylmethoxycarbonyloxy)succinimide 2-[N-[2-(BOC-AMINO)ETHYL]AMINO]ACETIC ACID Sodium bicarbonate Tetrahydrofuran Water

Preparation Products

FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH Suppliers

Global( 64)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
GL Biochem(Binhai) Ltd.	+86-021-61263370 +8615301650015	wuqiuyan@glschina.com	China	2975	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Sichuan Biosynce Pharmatech Co., Ltd.	+8619950309693	diane@biosynce.com	China	4871	58
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53900	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

Supplier	Advantage
GenicBio Limited	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
BOC Sciences	58
GL Biochem(Binhai) Ltd.	58
Nextpeptide Inc	58
LEAPCHEM CO., LTD.	58
Sichuan Biosynce Pharmatech Co., Ltd.	58
Aladdin Scientific	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Amadis Chemical Company Limited	58

141743-15-9(FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH)Related Search:

4-Boc-1-Fmoc-2-piperazinecarboxylic acid (R,S)-N-FMOC-N'-BOC-IMIDAZOLIDINE-2-CARBOXYLIC ACID (2S, 4S)-BOC-4-AMINO-1-FMOC-PYRROLIDINE-2-CARBOXYLIC ACID (2S, 4R)-BOC-4-AMINO-1-FMOC-PYRROLIDINE-2-CARBOXYLIC ACID (S)-1-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-4-(TERT-BUTOXYCARBONYL)PIPERAZINE-2-CARBOXYLIC ACID

(2S5R)-N-ALPHA-9-FLUORENYLMETHYLOXYCARBONYL-PYRROLIDINE-5-(N'-T-BUTYLOXYCARBONYL-AMINOMETHYL)-2-CARBOXYLIC ACID (R)-1-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-4-(TERT-BUTOXYCARBONYL)PIPERAZINE-2-CARBOXYLIC ACID FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH

1of2

Fmoc-N-(2-Boc-aminoethyl)glycine≥ 99% (HPLC) N-(9-FLUORENYLMETHOXYCARBONYL)-N-(2-TERT-BUTYLOXYCARBONYLAMINO-ETHYL)-GLYCINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-(BETA-T-BUTOXYCARBONYLAMINOETHYL)-GLYCINE FMOC-AEG(BOC)-OH FMOC-AEG-OH FMOC-BOCNHETGLY-OH FMOC-N-(2-BOC-AMINOETHYL)-GLYCINE FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLYCINE FMOC-N-(N-BETA-BOC-AMINOETHYL)-GLY-OH N-(9-FLUORENYLMETHYLOXYCARBONYL)-N-(2-T-BUTYLOXYCARBONYLAMINO-ETHYL)-GLYCINE N-(9-FLUOROENYLMETHYLOXYCARBONYL)-N-(2-T-BUTYLOXYCARBONYLAMINO-ETHYL)-GLYCINE Fmoc-N-(N-a-Boc-aminoethyl)-Gly-OH Fmoc-N-(2-Boc-aminoethyl)-Gly-OH Fmoc-N-(N-β-Boc-aminoethyl)-Gly-OH FMoc-N-(N-b-Boc-aMinoethyl)-Gly-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl N-(2-(Tert-Butoxy)Carbonyl aminoethyl)-Gly-OH 2-[9H-fluoren-9-ylmethoxycarbonyl-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]amino]acetic acid Glycine,N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- 2-[(2-{[(tert-butoxy)carbonyl]amino}ethyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid [(2-{[(tert-butoxy)carbonyl]amino}ethyl)[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid 141743-15-9