Boc-D-Ser(Bzl)-OH
- CAS No.
- 47173-80-8
- Chemical Name:
- Boc-D-Ser(Bzl)-OH
- Synonyms
- O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);N-BOC-O-BENZYL-D-SERINE;BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;BOC-L-SER(BZL)-OH;T-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
- CBNumber:
- CB5438415
- Molecular Formula:
- C15H21NO5
- Molecular Weight:
- 295.33
- MDL Number:
- MFCD00038248
- MOL File:
- 47173-80-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Boc-D-Ser(Bzl)-OH Novabiochem? | 8.53111 | 25g | $907 |
| Boc-D-Ser(Bzl)-OH ≥98.0% (HPLC) | 15078 | 5g | $414 |
| O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T) | B1863 | 1g | $53 |
| O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T) | B1863 | 5g | $170 |
| Boc-O-benzyl-L-serine | 261925 | 5g | $289 |
| More product size | |||
| Melting point | 58-60 °C(lit.) |
|---|---|
| alpha | -19 º (c=2 80% alcohol) |
| Boiling point | 437.02°C (rough estimate) |
| Density | 1.1454 (rough estimate) |
| refractive index | -20 ° (C=2, 80% EtOH) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | almost transparency in Methanol |
| pka | 3.53±0.10(Predicted) |
| form | Powder |
| color | White |
| BRN | 2665080 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1 |
| InChIKey | DMBKPDOAQVGTST-GFCCVEGCSA-N |
| SMILES | C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O |
| CAS DataBase Reference | 47173-80-8(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2924 29 70 | |||||||||
| HazardClass | IRRITANT | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Boc-D-Ser(Bzl)-OH price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.53111 | Boc-D-Ser(Bzl)-OH Novabiochem? | 47173-80-8 | 25g | $907 | 2026-03-19 | Buy |
| Sigma-Aldrich | 15078 | Boc-D-Ser(Bzl)-OH ≥98.0% (HPLC) | 47173-80-8 | 5g | $414 | 2026-03-19 | Buy |
| TCI Chemical | B1863 | O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T) | 47173-80-8 | 1g | $53 | 2026-03-19 | Buy |
| TCI Chemical | B1863 | O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T) | 47173-80-8 | 5g | $170 | 2026-03-19 | Buy |
| Usbiological | 261925 | Boc-O-benzyl-L-serine | 47173-80-8 | 5g | $289 | 2021-12-16 | Buy |
Boc-D-Ser(Bzl)-OH Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Uses
N-BOC-O-Benzyl-D-serine, is an amino acid derivative used in chemical synthesis and peptide chemistry.is used in preparation of substituted naphthyl thiadiazolidinones as protein tyrosine phosphatase degraders for treating cancer and metabolic diseases.
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Biological Activity
Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.
Synthesis
N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.
Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sichuan HongRi Pharma-Tech Co.,Ltd | +8618382028708 | ni@enlaibio.com | China | 1098 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 | Jerry@xhobio.com | China | 906 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13815 | 58 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
| GenicBio Limited | +86-21-37621270 | service@genicbio.com | CHINA | 991 | 58 |
View Lastest Price from Boc-D-Ser(Bzl)-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-29 | Boc-D-Ser(Bzl)-OH
47173-80-8
|
US $0.00 / Kg/Drum | 1KG | 98%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-04-29 | N-Boc-O-Benzyl-D-serine
47173-80-8
|
US $0.00 / KG | 1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd | |
 |
2026-04-29 | Boc-D-Ser(Bzl)-OH
47173-80-8
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd |
-
- Boc-D-Ser(Bzl)-OH
47173-80-8
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- N-Boc-O-Benzyl-D-serine
47173-80-8
- US $0.00 / KG
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
-
- Boc-D-Ser(Bzl)-OH
47173-80-8
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
47173-80-8(Boc-D-Ser(Bzl)-OH)Related Search:
1of4
