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Boc-D-Ser(Bzl)-OH

Boc-D-Ser(Bzl)-OH structure

CAS No.: 47173-80-8

Chemical Name:: Boc-D-Ser(Bzl)-OH

Synonyms: O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE;BOC-SER(BZL)-OH;BOC-SER(BZL);BOC-D-SER(BZL);BOC-O-BENZYL-L-SERINE;(R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid;(2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid;BOC-L-SER(BZL);(2R)-3-(benzylox;BOC-D-SER(BZL)-OH

CBNumber:: CB5438415

Molecular Formula:: C15H21NO5

Molecular Weight:: 295.33

MDL Number:: MFCD00038248

MOL File:: 47173-80-8.mol

MSDS File:: SDS

Last updated:2023-10-24 14:57:40

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Boc-D-Ser(Bzl)-OH Properties

Melting point	58-60 °C(lit.)
alpha	-19 º (c=2 80% alcohol)
Boiling point	437.02°C (rough estimate)
Density	1.1454 (rough estimate)
refractive index	-20 ° (C=2, 80% EtOH)
storage temp.	Sealed in dry,Room Temperature
solubility	almost transparency in Methanol
pka	3.53±0.10(Predicted)
form	Powder
color	White
BRN	2665080
InChI	InChI=1S/C15H21NO5/c1-15(2,3)21-14(19)16-12(13(17)18)10-20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1
InChIKey	DMBKPDOAQVGTST-GFCCVEGCSA-N
SMILES	C(O)(=O)[C@@H](COCC1=CC=CC=C1)NC(OC(C)(C)C)=O
CAS DataBase Reference	47173-80-8(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

20/21/22-36/37/38

Safety Statements

24/25-36-26

WGK Germany

HS Code

2924 29 70

HazardClass

IRRITANT

NFPA 704

	1
0		0

Boc-D-Ser(Bzl)-OH price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.53111	Boc-D-Ser(Bzl)-OH Novabiochem?	47173-80-8	25g	$196	2024-03-01	Buy
Sigma-Aldrich	15078	Boc-D-Ser(Bzl)-OH ≥98.0% (HPLC)	47173-80-8	5g	$413	2024-03-01	Buy
TCI Chemical	B1863	O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T)	47173-80-8	1g	$66	2024-03-01	Buy
TCI Chemical	B1863	O-Benzyl-N-(tert-butoxycarbonyl)-D-serine >98.0%(HPLC)(T)	47173-80-8	5g	$212	2024-03-01	Buy
Alfa Aesar	B22666	N-Boc-O-benzyl-D-serine, 99%	47173-80-8	5g	$180	2021-12-16	Buy

Product number	Packaging	Price	Buy
8.53111	25g	$196	Buy
15078	5g	$413	Buy
B1863	1g	$66	Buy
B1863	5g	$212	Buy
B22666	5g	$180	Buy

Boc-D-Ser(Bzl)-OH Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

N-BOC-O-Benzyl-D-serine, is an amino acid derivative used in chemical synthesis and peptide chemistry.is used in preparation of substituted naphthyl thiadiazolidinones as protein tyrosine phosphatase degraders for treating cancer and metabolic diseases.

Biological Activity

Boc-O-benzyl-D-serine is an inhibitor of the uptake of galactose and its derivatives. It has potent inhibitory activity against the uptake of galactose, glucose, and lactose. This drug is also effective in inhibiting the uptake of tetrazole, a substance that inhibits glycolysis. Boc-O-benzyl-D-serine is able to inhibit atherosclerotic lesions caused by piperidine, which has been shown to be synthesized from benzyl alcohol and piperidine. The oral administration of this compound can enhance fibroblast cells that are resistant to insulin.

Synthesis

N-Boc D-Se (500 mg, 2.43 mmol) dissolved in anhydrous DMF (4 mL) was slowly added to a dispersion of 60% NaH (204 mg, 5.1 mmol) in anhydrous DMF at 0 ° C. Stir the mixture at room temperature for 1 hour and cool to 0 ° C. Subsequently, benzyl bromide (0.29 mL, 2.43 mmol) was added and the mixture was heated to room temperature. After 4 hours of reaction, add saturated NH4Cl (1 mL) to quench the reaction. Finally, the product Boc-D-Ser(Bzl)-OH was obtained through purification.

Boc-D-Ser(Bzl)-OH synthesis

Synthesis of Boc-D-Ser(Bzl)-OH from Di-tert-butyl dicarbonate

Boc-D-Ser(Bzl)-OH Preparation Products And Raw materials

Raw materials

O-BENZYL-D-SERINE Di-tert-butyl dicarbonate Benzyl bromide

Preparation Products

MK-677 Carbamic acid, N-[(1R)-1-formyl-2-(phenylmethoxy)ethyl]-, 1,1-dimethylethyl ester Boc-N-Me-D-Ser(Bzl)-OH

Boc-D-Ser(Bzl)-OH Suppliers

Global( 260)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	+86-028-64841719 +8618980456393	daisy@enlaibio.com	China	1369	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
AB PharmaTech,LLC	323-480-4688		United States	989	55
GenicBio Limited	+86-21-37621270	service@genicbio.com	CHINA	991	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58

Supplier	Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Shanghai Time Chemicals CO., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
AB PharmaTech,LLC	55
GenicBio Limited	58
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58

View Lastest Price from Boc-D-Ser(Bzl)-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-25	Boc-D-Ser(Bzl)-OH 47173-80-8	US $0.00-0.00 / kg	1kg	98%	1T+	Sichuan HongRi Pharma-Tech Co.,Ltd
2021-09-29	Boc-D-Ser(Bzl)-OH 47173-80-8	US $0.00 / Kg/Drum	1KG	98%min	500kgs	WUHAN FORTUNA CHEMICAL CO., LTD
2020-01-06	Boc-D-Ser(Bzl)-OH 47173-80-8	US $1.00 / g	1g	98%	100KG	Sichuan Jiaying Lai Technology Co.,LTD

Boc-D-Ser(Bzl)-OH
47173-80-8
US $0.00-0.00 / kg
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Boc-D-Ser(Bzl)-OH
47173-80-8
US $0.00 / Kg/Drum
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Boc-D-Ser(Bzl)-OH
47173-80-8
US $1.00 / g
98%
Sichuan Jiaying Lai Technology Co.,LTD

Boc-D-Ser(Bzl)-OH Spectrum

N-Boc-O-Benzyl-D-serine(47173-80-8)MS N-Boc-O-Benzyl-D-serine(47173-80-8)¹HNMR N-Boc-O-Benzyl-D-serine(47173-80-8)¹³CNMR N-Boc-O-Benzyl-D-serine(47173-80-8)IR1 N-Boc-O-Benzyl-D-serine(47173-80-8)IR2

47173-80-8(Boc-D-Ser(Bzl)-OH)Related Search:

Benzyl chloride D-Serine Benzyl benzoate L-Homoserine tert-Butanol

Boc-Ser(tBu)-OH N-Carbobenzyloxyglycine Benzyl bromide DL-Serine Benzyltriethylammonium chloride

Benzyl alcohol L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Boc-Aib-OH D-Cycloserine Benzyltrimethylammonium chloride

Boc-O-benzyl-L-serine, N-(tert-Butoxycarbonyl)-O-benzyl-L-serine,N-BOC-O-Benzyl-L-serine,N-T-BOC-O-BENZYL-L-SERINE CRYSTALLINE BOC-GLY-LEU-OH Boc-His(Trt)-OH

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(2R)-2-(tert-butoxycarbonylamino)-3-(phenylmethoxy)propanoic acid (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(phenylmethoxy)propanoic acid (2R)-2-[(tert-butoxy-oxomethyl)amino]-3-(phenylmethoxy)propanoic acid (2R)-3-(benzyloxy)-2-(tert-butoxycarbonylamino)propionic acid L-Serine, N-((1,1-dimethylethoxy)carbonyl)-O-(phenylmethyl)- Boc-D-Ser(Bzl)-OH, >=98% BOC-D-SERINE(BZL)-OH BOC-D-SER(BZL)-OH BOC-SERINE(BZL)-OH BOC-(S)-2-AMINO-3-BENZYLOXYPROPIONIC ACID BOC-O-BENZYL-D-SERINE BOC-(R)-2-AMINO-3-BENZYLOXYPROPIONIC ACID BOC-L-SER(BZL)-OH BOC-L-SERINE (BZL) BOC-L-SER(BZL) O-Benzyl-N-(tert-butoxycarbonyl)-D-serine Boc-O-benzyl-D-serine≥ 99.5% (HPLC) NALPHA-tert-Butoxycarbonyl-O-benzyl-D-serine N-BOC-O-Benzyl-D-serine,98% N-t-BOC-O-Benzyl-D-serine N-Boc-O-Benzyl-D-ser Boc-D-Ser(Bzl)-OH Boc-O-benzyl-D-Serine N-Boc-O-benzyl-D-serine Boc-D-Ser(Bzl)-OH T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE T-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE TBOC-L-SERINE (BZL) N-ALPHA-T-BOC-O-BENZYL-L-SERINE N-ALPHA-T-BOC-O-BENZYL-D-SERINE N-ALPHA-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE N-ALPHA-T-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE N-ALPHA-TERT-BOC-O-BENZYL-L-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-D-SERINE N-ALPHA-TERT-BUTYLOXYCARBONYL-O-BENZYL-L-SERINE N-BOC-O-BENZYL-D-SERINE Boc-DL-Ser(Bzl)-OH N-TERT-BUTOXYCARBONYL-O-BENZYL-D-SERINE N-T-BUTOXYCARBONYL-O-BENZYL-L-SERINE (Tert-Butoxy)Carbonyl D-Ser(Bzl)-OH (2R)-3-(benzylox O-Benzyl-N-Boc-D-serine O-Benzyl-N-(tert-butoxycarbonyl)-D-serine > D-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- BOC-SER(BZL)-OH BOC-SER(BZL) BOC-O-BENZYL-L-SERINE (R)-3-(benzyloxy)-2-((tert-butoxycarbonyl)aMino)propanoic acid O-BENZYL-N-(TERT-BUTOXYCARBONYL)-D-SERINE BOC-D-SER(BZL) (2R)-3-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}propanoic acid N-[(1,1-Dimethylethoxy)carbonyl]-O-(phenylmethyl)-D-serine (s)-(+)-3-Benzyloxy-2-(Boc-amino)-1-propanol BOC-D-Ser(OBZL)-OH 47173-80-8 47473-80-8 47173-80-6 C15H20NO5 Specialty Synthesis Peptide Synthesis