ChemicalBook >> CAS DataBase List >>PF-06860932
PF-06860932
- CAS No.
- 2226970-01-8
- Chemical Name:
- PF-06860932
- Synonyms
- PF-06860932;CFTR corrector 6;7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-
- CBNumber:
- CB54667293
- Molecular Formula:
- C22H13F4N9
- Molecular Weight:
- 479.39
- MDL Number:
- MFCD34470807
- MOL File:
- 2226970-01-8.mol
Last updated:2024-07-02 08:55:11
PF-06860932 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0135420 | CFTRcorrector6 | 2226970-01-8 | 5mg | $480 | 2021-12-16 | Buy |
ChemScene | CS-0135420 | CFTRcorrector6 | 2226970-01-8 | 10mg | $800 | 2021-12-16 | Buy |
ChemScene | CS-0135420 | CFTRcorrector6 | 2226970-01-8 | 25mg | $1550 | 2021-12-16 | Buy |
ChemScene | CS-0135420 | CFTRcorrector6 | 2226970-01-8 | 50mg | $2400 | 2021-12-16 | Buy |
ChemScene | CS-0135420 | CFTRcorrector6 | 2226970-01-8 | 100mg | $3600 | 2021-12-16 | Buy |
PF-06860932 Chemical Properties,Uses,Production
Biological Activity
CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].
References
[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1
PF-06860932 Preparation Products And Raw materials
Raw materials
Preparation Products
PF-06860932 Suppliers
Global( 7)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Kaixin Chemical (Hong Kong) Limited | 010-88886666-01 13112345678 | loyson@tcypharm.com | China | 595 | 55 |
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd. | 15990591583 | China | 5570 | 58 | |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 23980 | 58 |
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd | 021-59167510 18117107507 | vip@med-life.cn | China | 5012 | 58 |
RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9268 | 58 |
PF-06860932
CFTR corrector 6
7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-
2226970-01-8