2,6-Difluoroaniline
- CAS No.
- 5509-65-9
- Chemical Name:
- 2,6-Difluoroaniline
- Synonyms
- 2,6-Difuluoroaniline;2,6-DIFLUOROBENZENAMINE;26DFA;NSC 127234;JACS-5509-65-9;6-Difluoroaniline;Abesili Impurity 8;2,6-DIFLUOROANILINE;2,6- twofluoro aniline;2,6-Difluoroaniline>
- CBNumber:
- CB5478710
- Molecular Formula:
- C6H5F2N
- Molecular Weight:
- 129.11
- MDL Number:
- MFCD00007655
- MOL File:
- 5509-65-9.mol
- MSDS File:
- SDS
| Boiling point | 51-52 °C/15 mmHg (lit.) |
|---|---|
| Density | 1.199 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 110 °F |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | Chloroform, Ethyl Acetate (Slightly) |
| form | Liquid |
| pka | 1.81±0.10(Predicted) |
| Specific Gravity | 1.28 |
| color | Clear yellow to brown |
| Water Solubility | Slightly soluble in water. |
| BRN | 2802697 |
| Stability | Hygroscopic |
| InChIKey | ODUZJBKKYBQIBX-UHFFFAOYSA-N |
| CAS DataBase Reference | 5509-65-9(CAS DataBase Reference) |
| FDA UNII | 943G3H8895 |
| NIST Chemistry Reference | 2,6-Difluoroaniline(5509-65-9) |
| EPA Substance Registry System | 2,6-Difluoroaniline (5509-65-9) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H226-H302+H312+H332-H317 | |||||||||
| Precautionary statements | P210-P233-P280-P301+P312-P303+P361+P353-P304+P340+P312 | |||||||||
| Hazard Codes | Xn,Xi,F | |||||||||
| Risk Statements | 10-20/21/22-36/37/38 | |||||||||
| Safety Statements | 36-36/37/39-26-23-16-16/23/26/36/37/39-24/25 | |||||||||
| RIDADR | UN 1993 3/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10-23 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29214210 | |||||||||
| NFPA 704 |
|
2,6-Difluoroaniline price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 196614 | 2,6-Difluoroaniline ≥97% | 5509-65-9 | 5g | $54.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | 196614 | 2,6-Difluoroaniline ≥97% | 5509-65-9 | 25g | $72.1 | 2024-03-01 | Buy |
| TCI Chemical | D1635 | 2,6-Difluoroaniline >98.0%(GC) | 5509-65-9 | 5g | $26 | 2024-03-01 | Buy |
| TCI Chemical | D1635 | 2,6-Difluoroaniline >98.0%(GC) | 5509-65-9 | 25g | $77 | 2024-03-01 | Buy |
| Alfa Aesar | A13020 | 2,6-Difluoroaniline, 98% | 5509-65-9 | 5g | $37.65 | 2024-03-01 | Buy |
2,6-Difluoroaniline Chemical Properties,Uses,Production
Chemical Properties
clear yellow to brown liquid
Uses
2,6-Difluoroaniline was used in the synthesis of:
- N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compound
- series of 2,6,9-trisubstituted purine inhibitors of p38α kinase
- substituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate
Uses
2,6-Difluoroaniline and several related primary amines are oxidized in chloroform by peroxybenzoic acid to the corresponding nitroso compounds. For example, treatment of 2,6-difluoroaniline with sodium azide can obtain 4-fluoro-2,1,3-benzoxadiazole, and the product is nitrified to obtain 7-nitro derivatives[1]. 2,6-Difluoroaniline is an important raw material and intermediate in organic synthesis, medicine, pesticides, dyes and other fields.
Uses
2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.
Toxics Screening Level
The initial threshold screening level (ITSL) for 2,6-difluoroaniline (DFA) is 2.0 μg/m3 based on an annual averaging time.
References
[1] Nunno L, et al. Oxidation of substituted anilines to nitroso-compounds. J. Chem. Soc. C, 1970; 9: 1433-1434.
2,6-Difluoroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Ningxia Jinhua Chemical Co.,Ltd | +86-025-52279164 +8615996340606 | info@nxjhchem.com | China | 79 | 58 |
| Gansu Jinyuantai New Material Co., Ltd. | +86-025-86618065 +86-13914714331 | marketing@royal-chem.com | China | 94 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 +86-13288715578 | sales@hbmojin.com | China | 12749 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20207 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 | sales@richfortunechem.com | China | 304 | 57 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
View Lastest Price from 2,6-Difluoroaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-07 | 2,6-Difluoroaniline
5509-65-9
|
US $500.00 / g | 100g | 99% | 200ton | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-07-07 | 2,6-Difluoroaniline
5509-65-9
|
US $0.00 / KG | 1000KG | 99 | 20000 | Gansu Jinyuantai New Material Co., Ltd. | |
 |
2025-06-24 | 2,6-Difluoroaniline
5509-65-9
|
US $0.00-0.00 / KG | 1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 2,6-Difluoroaniline
5509-65-9
- US $500.00 / g
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 2,6-Difluoroaniline
5509-65-9
- US $0.00 / KG
- 99
- Gansu Jinyuantai New Material Co., Ltd.
-
- 2,6-Difluoroaniline
5509-65-9
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
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