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2,6-Difluoroaniline

2,6-Difluoroaniline structure

CAS No.: 5509-65-9

Chemical Name:: 2,6-Difluoroaniline

Synonyms: 2,6-DIFLUOROBENZENAMINE;2,6-Difuluoroaniline;2,6-DifluorophenylaMine;2,6-DifluorobenzeneaMine;26DFA;NSC 127234;JACS-5509-65-9;6-Difluoroaniline;Abesili Impurity 8;2,6-DIFLUOROANILINE

CBNumber:: CB5478710

Molecular Formula:: C6H5F2N

Molecular Weight:: 129.11

MDL Number:: MFCD00007655

MOL File:: 5509-65-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:43:18

Product description	Number	Pack Size	Price
2,6-Difluoroaniline ≥97%	196614	5g	$59.7
2,6-Difluoroaniline ≥97%	196614	25g	$79.1
2,6-Difluoroaniline >98.0%(GC)	D1635	5g	$23
2,6-Difluoroaniline >98.0%(GC)	D1635	25g	$66
2,6-Difluoroaniline	TRC-D445530-5G	5g	$77
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2,6-Difluoroaniline Properties

Boiling point	51-52 °C/15 mmHg (lit.)
Density	1.199 g/mL at 25 °C (lit.)
refractive index	n20/D 1.508(lit.)
Flash point	110 °F
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	Chloroform, Ethyl Acetate (Slightly)
form	Liquid
pka	1.81±0.10(Predicted)
Specific Gravity	1.28
color	Clear yellow to brown
Water Solubility	Slightly soluble in water.
BRN	2802697
Stability	Hygroscopic
InChI	1S/C6H5F2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2
InChIKey	ODUZJBKKYBQIBX-UHFFFAOYSA-N
SMILES	Nc1c(F)cccc1F
CAS DataBase Reference	5509-65-9(CAS DataBase Reference)
FDA UNII	943G3H8895
NIST Chemistry Reference	2,6-Difluoroaniline(5509-65-9)
EPA Substance Registry System	2,6-Difluoroaniline (5509-65-9)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Warning

Hazard statements

H226-H302+H312+H332-H317

Precautionary statements

P210-P233-P280-P301+P312-P303+P361+P353-P304+P340+P312

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xn,Xi,F

Risk Statements

10-20/21/22-36/37/38

Safety Statements

36-36/37/39-26-23-16-16/23/26/36/37/39-24/25

RIDADR

UN 1993 3/PG 3

WGK Germany

8-10-23

Hazard Note

Irritant

TSCA

TSCA listed

HazardClass

PackingGroup

III

HS Code

29214210

Storage Class

3 - Flammable liquids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Flam. Liq. 3
Skin Sens. 1

Limited Quantities

5.0 L (1.3 gallons) (liquid)

Excepted Quantities

Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)

NFPA 704

	2
2		0

2,6-Difluoroaniline price More Price(64)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	196614	2,6-Difluoroaniline ≥97%	5509-65-9	5g	$59.7	2026-04-30	Buy
Sigma-Aldrich	196614	2,6-Difluoroaniline ≥97%	5509-65-9	25g	$79.1	2026-04-30	Buy
TCI Chemical	D1635	2,6-Difluoroaniline >98.0%(GC)	5509-65-9	5g	$23	2026-04-30	Buy
TCI Chemical	D1635	2,6-Difluoroaniline >98.0%(GC)	5509-65-9	25g	$66	2026-04-30	Buy
TRC	TRC-D445530-5G	2,6-Difluoroaniline	5509-65-9	5g	$77	2026-06-03	Buy

Product number	Packaging	Price	Buy
196614	5g	$59.7	Buy
196614	25g	$79.1	Buy
D1635	5g	$23	Buy
D1635	25g	$66	Buy
TRC-D445530-5G	5g	$77	Buy

2,6-Difluoroaniline Chemical Properties,Uses,Production

Chemical Properties

clear yellow to brown liquid

Uses

2,6-Difluoroaniline was used in the synthesis of:

N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compound
series of 2,6,9-trisubstituted purine inhibitors of p38α kinase
substituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate

Uses

2,6-Difluoroaniline and several related primary amines are oxidized in chloroform by peroxybenzoic acid to the corresponding nitroso compounds. For example, treatment of 2,6-difluoroaniline with sodium azide can obtain 4-fluoro-2,1,3-benzoxadiazole, and the product is nitrified to obtain 7-nitro derivatives[1]. 2,6-Difluoroaniline is an important raw material and intermediate in organic synthesis, medicine, pesticides, dyes and other fields.

Uses

2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.

Toxics Screening Level

The initial threshold screening level (ITSL) for 2,6-difluoroaniline (DFA) is 2.0 μg/m3 based on an annual averaging time.

References

[1] Nunno L, et al. Oxidation of substituted anilines to nitroso-compounds. J. Chem. Soc. C, 1970; 9: 1433-1434.

2,6-Difluoroaniline Preparation Products And Raw materials

Raw materials

2,6-Difluorobenzamide

Preparation Products

4-(CHLOROSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE DBD-PZ Abemaciclib N1-(2,6-DIFLUORO-3-NITROPHENYL)ACETAMIDE 4-(N,N-DIMETHYLAMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE

4-Bromo-2,6-difluoroaniline 4-Amino-2,6-difluorophenol 2,6-Difluoro-4-nitrophenol 2,6-DIFLUORO-4-NITROANILINE 4-FLUORO-2,1,3-BENZOXADIAZOLE

4-Fluoro-7-nitrobenzofurazan 2,6-Difluoronitrobenzene 2,6-Difluorophenol ETHYL 2-(2,6-DIFLUOROANILINO)-2-OXOACETATE 5-Chloro-N-(2,6-difluorophenyl)pyrazine-2-carboxamide

Benzenamine, 2,6-difluoro-N-(2-methylpropyl)- 1-Bromo-2,6-difluorobenzene

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2,6-Difluoroaniline Suppliers

Global( 598)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Ningxia Jinhua Chemical Co.,Ltd	+86-025-52279164	info@nxjhchem.com	China	79	58
Gansu Jinyuantai New Material Co., Ltd.	+86-025-86618065 +86-13914714331	marketing@royal-chem.com	China	95	58
Shanghai Cube Chemical Co., Ltd.	+86-02156500520 +86-18116101847	kevin.li@cubechem.com	China	43	58
Hebei Chuanghai Biotechnology Co., Ltd	+86-15350571055	Sibel@chuanghaibio.com	China	8737	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325	sales1@chuanghaibio.com	China	5218	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20111	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29626	60
Dalian Richfortune Chemicals Co., Ltd	+86-86-411-84820922 +86-8613904096939	sales@richfortunechem.com	China	305	57
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21531	55
Fluoropharm Co., Ltd.	+86-0571-85586753 +86-13336034509	sales@fluoropharm.com	China	1444	60

Supplier	Advantage
Ningxia Jinhua Chemical Co.,Ltd	58
Gansu Jinyuantai New Material Co., Ltd.	58
Shanghai Cube Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Dalian Richfortune Chemicals Co., Ltd	57
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60

View Lastest Price from 2,6-Difluoroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-11	2,6-Difluoroaniline 5509-65-9		1000KG	99	20000	Gansu Jinyuantai New Material Co., Ltd.
2026-08-11	2,6-Difluoroaniline 5509-65-9	$3.00-10.00	1KG	99%		Henan Fengda Chemical Co., Ltd
2026-06-30	2,6-Difluoroaniline 5509-65-9		1KG	99.0%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

2,6-Difluoroaniline
5509-65-9
$0.00
99
Gansu Jinyuantai New Material Co., Ltd.

2,6-Difluoroaniline
5509-65-9
$3.00-10.00
99%
Henan Fengda Chemical Co., Ltd

2,6-Difluoroaniline
5509-65-9
99.0%
Shaanxi Dideu New Materials Co. Ltd

2,6-Difluoroaniline Spectrum

2,6-Difluoroaniline(5509-65-9)MS 2,6-Difluoroaniline(5509-65-9)¹HNMR 2,6-Difluoroaniline(5509-65-9)IR1 2,6-Difluoroaniline(5509-65-9)Raman

5509-65-9(2,6-Difluoroaniline)Related Search:

N,N-Dimethylaniline 2-Fluoroaniline Diphenylamine 2,4,5-Trifluoroaniline 4-(Trifluoromethoxy)aniline

3,5-Difluoroaniline N,N-Dimethyl-1,4-phenylenediamine Sodium diphenylamine-4-sulfonate 4-Fluoroaniline 2,6-Difluorobenzylamine

2,3,6-TRIFLUOROANILINE 3,4-Difluoroaniline 2,3,4,6-TETRAFLUORONITROBENZENE 2,6-DIFLUOROPHENYL ISOCYANATE 4-AMINO-2,3,5,6-TETRAFLUOROBENZOIC ACID

4-AMINO-2,3,5,6-TETRAFLUOROBENZAMIDE PENTAFLUORONITROBENZENE 2,4,6-Trifluoroaniline

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Benzenamine, 2,6-difluoro- 2,6-DIFLUOROANILINE 2,6-DIFLUOROANILINE, 97+% 2,6-Difluoroaniline,98% 2,6-Difluoroaniline,min.97% 2,6-Difluoroaniline 98% 2,6-Difluoroaniline, min. 97% 2,6-Difuluorobenzenamine NSC 127234 6-Difluoroaniline 2-Amino-1,3-difluorobenzene 2,6-Difluoroaniline, 97% 5ML 2,6- twofluoro aniline 2,6-Difluoroaniline 98%, 6-Difluoroaniline 98% 2,6-Difluoroaniline 98% Min. JACS-5509-65-9 2,6-Difluoroaniline> 2,6-Difluoroaniline ISO 9001：2015 REACH 2,6-Difuluoroaniline Abemaciclib Impurity 9 Vandetanib Impurity 13 Abesili Impurity 8 2,6-Difluoroaniline, 96% 26DFA 2,6-DifluorobenzeneaMine 2,6-DifluorophenylaMine 2,6-DIFLUOROBENZENAMINE 5509-65-9 F2C6H3NH2 C6F2H5N1 C2 to C6 Amines Building Blocks Organic Building Blocks Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene Miscellaneous Fluorobenzene Series Amines C2 to C6 Nitrogen Compounds bc0001