Triethyl acetyl citrate
- CAS No.
- 77-89-4
- Chemical Name:
- Triethyl acetyl citrate
- Synonyms
- ACETYL TRIETHYL CITRATE;ATEC;O-AcetyL;triethyl 2-acetoxypropane-1,2,3-tricarboxylate;Uniplex 82;Triethyl O;citroflexa2;Citroflex A 2;Trithylcitratc;ethyl acetylcitrate
- CBNumber:
- CB5483819
- Molecular Formula:
- C14H22O8
- Molecular Weight:
- 318.32
- MDL Number:
- MFCD00049378
- MOL File:
- 77-89-4.mol
- MSDS File:
- SDS
| Melting point | -42°C |
|---|---|
| Boiling point | 228-229 °C/100 mmHg (lit.) |
| Density | 1.136 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble 1 in 140 of water; miscible with acetone, ethanol, and propan-2-ol. |
| color | Colourless |
| Odor | odorless |
| BRN | 1804947 |
| LogP | 2.170 (est) |
| Indirect Additives used in Food Contact Substances | ACETYL TRIETHYL CITRATE |
| FDA 21 CFR | 175.105; 175.300; 175.320; 178.3910; 181.27 |
| CAS DataBase Reference | 77-89-4(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | 5WBR36T90E |
| NIST Chemistry Reference | 1,2,3-Propanetricarboxylic acid, 2-acetoxy-, triethyl ester(77-89-4) |
| EPA Substance Registry System | 1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester (77-89-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Safety Statements | 23-24/25 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | GE8225000 | |||||||||
| HS Code | 2918150000 | |||||||||
| NFPA 704 |
|
Triethyl acetyl citrate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 388351 | Triethyl 2-acetylcitrate 99% | 77-89-4 | 500ml | $61.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1009923 | Acetyltriethyl citrate United States Pharmacopeia (USP) Reference Standard | 77-89-4 | 500mg | $450 | 2022-05-15 | Buy |
| TCI Chemical | A0086 | Triethyl O-Acetylcitrate >97.0%(GC) | 77-89-4 | 25g | $33 | 2024-03-01 | Buy |
| TCI Chemical | A0086 | Triethyl O-Acetylcitrate >97.0%(GC) | 77-89-4 | 500g | $68 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR1157 | Triethyl 2-acetylcitrate Pharmaceutical Secondary Standard; Certified Reference Material | 77-89-4 | 1g | $170 | 2024-03-01 | Buy |
Triethyl acetyl citrate Chemical Properties,Uses,Production
Chemical Properties
Acetyltriethyl citrate occurs as a clear, odorless, practically colorless oily liquid.
Uses
Triethyl O-Acetylcitrate is used in the preparation of poly(lactic) acid biodegradable and flexible films, acting as a plasticizer. Also used in the synthesis of control-release capsules containing polymeric coatings.
Uses
ATEC is produced by the reaction of citric acid triethyl ester with acetic acid anhydride. It is used as a solvent plasticizer for cellulose nitrate and cellulose acetate.
Production Methods
Acetyltriethyl citrate is prepared by the esterification of citric acid with ethanol followed by acylation with acetic anhydride.
Definition
Aqueous-based pharmaceutical coat- ings.
General Description
Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Triethyl 2-acetylcitrate is widely used in hydrophilic adhesives for medications and in biodegradable composition for papermaking and nonwoven production.
Pharmaceutical Applications
Acetyltriethyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads and granules for taste masking, immediate release, sustained-release and enteric formulations. It is also used in diffusion-controlled release drug delivery systems.
Safety
Acetyltriethyl citrate is used in oral pharmaceutical formulations
and is generally regarded as a nontoxic and nonirritating material.
However, ingestion of large quantities may be harmful.
LD50 (cat, oral): 8.5 g/kg
LD50 (mouse, IP): 1.15 g/kg
LD50 (rat, oral): 7 g/kg
storage
Acetyltriethyl citrate should be stored in dry, closed containers at temperatures not exceeding 388℃. When stored in accordance with these conditions, acetyltriethyl citrate is a stable product.
Incompatibilities
Acetyltriethyl citrate is incompatible with strong alkalis and oxidizing materials.
Regulatory Status
Approved in the USA for direct food contact in food films.
Triethyl acetyl citrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
View Lastest Price from Triethyl acetyl citrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-10-21 | Triethyl acetyl citrate
77-89-4
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-10-14 | Triethyl acetyl citrate
77-89-4
|
US $20.00-1.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-09-06 | Triethyl acetyl citrate
77-89-4
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- Triethyl acetyl citrate
77-89-4
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Triethyl acetyl citrate
77-89-4
- US $20.00-1.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- Triethyl acetyl citrate
77-89-4
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.