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Aumitin
- CAS No.
- 946293-78-3
- Chemical Name:
- Aumitin
- Synonyms
- Aumitin;inhibit,Autophagy,Aumitin,Inhibitor;Benzamide, 2-chloro-N-[4-[[4-methyl-6-(phenylamino)-2-pyrimidinyl]amino]phenyl]-
- CBNumber:
- CB54844496
- Molecular Formula:
- C24H20ClN5O
- Molecular Weight:
- 429.9
- MDL Number:
- MFCD09238311
- MOL File:
- 946293-78-3.mol
Last updated:2023-09-20 16:43:00
Aumitin Chemical Properties,Uses,Production
Biological Activity
Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].
References
[1]. Robke L, et al. Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chem Sci. 2018 Feb 26;9(11):3014-3022.
Aumitin Preparation Products And Raw materials
Raw materials
Preparation Products
Aumitin Suppliers
Global( 15)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2982 | 58 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9445 | 58 |
Shanghai Yu Ben Biotechnology Co., Ltd. | 15502154572 | yuben012@sina.com | China | 503 | 58 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
Chunchuang (Wuhan) Technology Co., Ltd | 15342225168 | yutianchun2007@126.com | China | 9964 | 58 |
Wuhan Shanhai Zhihe Biotechnology Co., Ltd. | 17771424646 | shoubull@126.com | China | 965 | 58 |
Aumitin
inhibit,Autophagy,Aumitin,Inhibitor
Benzamide, 2-chloro-N-[4-[[4-methyl-6-(phenylamino)-2-pyrimidinyl]amino]phenyl]-
946293-78-3