Pomalidomide-PEG4-CO2H
- CAS No.
- 2138440-81-8
- Chemical Name:
- Pomalidomide-PEG4-CO2H
- Synonyms
- Pomalidomide-PEG4-COOH;Poma-PEG4-COOH;Pomalidomide-PEG4-CO2H;POMALIDOMIDE-PEG4-CO 2 H;Pomalidomide 4'-PEG4-acid;Thalidomide-NH-PEG4-C2-COOH;1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12-tetraoxapentadecan-15-oic Acid;1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid;Propanoic acid, 3-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-;1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid, Crosslinker–E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
- CBNumber:
- CB54846410
- Molecular Formula:
- C24H31N3O10
- Molecular Weight:
- 521.52
- MDL Number:
- MFCD32173789
- MOL File:
- 2138440-81-8.mol
Last updated:2024-04-01 13:48:23
Pomalidomide-PEG4-CO2H Chemical Properties,Uses,Production
Uses
Protein degrader builiding block Pomalidomide-PEG4-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition and E3 ligase ligand.
storage
Desiccate at RT
Pomalidomide-PEG4-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
Pomalidomide-PEG4-CO2H Suppliers
Global( 23)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2893 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| ChemShuttle, Inc. | 0510-83588313-802 18800520310; | sales@chemshuttle.com | China | 3009 | 62 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9440 | 58 |
| Aikon International Limited | 025-58851090 13611564524 | lwan@aikonchem.com | China | 15952 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4955 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1285 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
View Lastest Price from Pomalidomide-PEG4-CO2H manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | Pomalidomide-PEG4-COOH
2138440-81-8
|
US $0.00 / mg | 250mg | >98.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
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- Pomalidomide-PEG4-COOH
2138440-81-8
- US $0.00 / mg
- >98.00%
- Xian confluore Biological Technology Co., Ltd.
2138440-81-8(Pomalidomide-PEG4-CO2H)Related Search:
E3 Ligase Ligand-Linker Conjugates 1
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG1-azide
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG5-CO2H
POMALIDOMIDE-PEG1-CO2H
Pomalidomide-PEG3-Amine HCl salt
1of4
POMALIDOMIDE-PEG4-CO 2 H
Pomalidomide-PEG4-CO2H
1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
Pomalidomide-PEG4-COOH
Thalidomide-NH-PEG4-C2-COOH
Propanoic acid, 3-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]-
1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12-tetraoxapentadecan-15-oic Acid
1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid, Crosslinker–E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
Poma-PEG4-COOH
Pomalidomide 4'-PEG4-acid
2138440-81-8
peg