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5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one structure

CAS No.: 885-70-1

Chemical Name:: 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one

Synonyms: 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;LS 75;Pirenzepine EP Impurity B;11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one;5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE;5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one;1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro-

CBNumber:: CB5488339

Molecular Formula:: C12H9N3O

Molecular Weight:: 211.22

MDL Number:: MFCD00190169

MOL File:: 885-70-1.mol

MSDS File:: SDS

Last updated:2025-10-23 17:25:30

Product description	Number	Pack Size	Price
5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one	D446720	2.5g	$105
5,6-Dihydro-6-oxo-11H-pyrido-[2,3-b][1,4]benzodiazepine 98%	070862	25g	$208
5,11-DIHYDROPYRIDO[2,3-BETA][1,4]BENZODIAZEPIN-6-ONE 95.00%	CHM0165648	25G	$1268.19
5,11-DIHYDROPYRIDO[2,3-BETA][1,4]BENZODIAZEPIN-6-ONE 95.00%	CHM0165648	5L	$6462.5
5,6-Dihydro-6-oxo-11H-pyrido-[2,3-b][1,4]benzodiazepine 98%	070862	1g	$30
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5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Properties

Melting point	292-293℃
Boiling point	336℃
Density	1.275
Flash point	157℃
storage temp.	Refrigerator, under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	Solid
pka	11.58±0.20(Predicted)
color	Light Beige to Beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D446720	5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one	885-70-1	2.5g	$105	2021-12-16	Buy
Matrix Scientific	070862	5,6-Dihydro-6-oxo-11H-pyrido-[2,3-b][1,4]benzodiazepine 98%	885-70-1	25g	$208	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0165648	5,11-DIHYDROPYRIDO[2,3-BETA][1,4]BENZODIAZEPIN-6-ONE 95.00%	885-70-1	25G	$1268.19	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0165648	5,11-DIHYDROPYRIDO[2,3-BETA][1,4]BENZODIAZEPIN-6-ONE 95.00%	885-70-1	5L	$6462.5	2021-12-16	Buy
Matrix Scientific	070862	5,6-Dihydro-6-oxo-11H-pyrido-[2,3-b][1,4]benzodiazepine 98%	885-70-1	1g	$30	2021-12-16	Buy

Product number	Packaging	Price	Buy
D446720	2.5g	$105	Buy
070862	25g	$208	Buy
CHM0165648	25G	$1268.19	Buy
CHM0165648	5L	$6462.5	Buy
070862	1g	$30	Buy

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Chemical Properties,Uses,Production

Chemical Properties

Light yellow crystals. Melting point 283-285℃ (286-288℃).

Uses

5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, can be used in the synthesis of fluorescent pirenzepine derivatives, used as potential bitopic ligands of the Human M1 Muscarinic receptor.

Synthesis

Synthesis_885-70-1
In a 1000 ml reaction flask,Add 600 ml of butanol,100 g of 2-amino-N- (2-chloropyridyl-3-yl) benzamide,2 ml of concentrated sulfuric acid,The reaction was refluxed for 3 hours at a reaction temperature of 80 C,Cooled to room temperature,filter,Washed with acetone,50-60 C in vacuo to give 98 g of a pale yellow solid product,Yield 98percent, purity 99percent.

References

[1] Patent: CN106432227, 2017, A. Location in patent: Paragraph 0019; 0020
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 17, p. 4300 - 4315
[3] Journal of Medicinal Chemistry, 1993, vol. 36, # 15, p. 2107 - 2114
[4] Collection of Czechoslovak Chemical Communications, 1988, vol. 53, # 8, p. 1820 - 1844
[5] Patent: WO2006/8118, 2006, A1. Location in patent: Page/Page column 20

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate N-(2-CHLOROPYRIDIN-3-YL)-2-NITROBENZAMIDE 2-Chloro-3-pyridinamine 2-Nitrobenzoyl chloride 2-AMINO-N-(2-CHLOROPYRIDIN-3-YL)BENZAMIDE

Methyl anthranilate tert-Butanol Sulfuric acid

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Preparation Products

5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepine-6-thione

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Suppliers

Global( 85)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Win-Win chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	14304	58
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	dominicguo@gk-bio.com	CHINA	9414	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
Shanghai Quedan biology science and technology co., ltd	+86-13004146052	lnzc@quedan.com.cn	China	1022	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Win-Win chemical CO., Limited	58
Baoji Guokang Healthchem co.,ltd	58
CR Corporation Limited	58
Nextpeptide Inc	58
Labnetwork lnc.	58
Shanghai Quedan biology science and technology co., ltd	58

View Lastest Price from 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-15	2-CHLORO-4-FLUORO-5-METHYL ANILINE 116759-33-2	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co
	2020-01-15	5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE 885-70-1	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

2-CHLORO-4-FLUORO-5-METHYL ANILINE
116759-33-2
US $1.00 / KG
99%
Career Henan Chemical Co

5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE
885-70-1
US $1.00 / KG
99%
Career Henan Chemical Co

885-70-1(5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one)Related Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 11-[[4-[4-(DIETHYLAMINO)BUTYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE BIBN 99 5,11-Dihydro-11-chloroacetyl-6H-pyrido[2,3-b][1,4]benzodiazepine-6-one Pirenzepine

AF-DX 384 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-(1H-imidazol -1-ylacetyl)-, hydrate Pirenzepine hydrochloride tripitramine

11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE PIRENZEPINE, [N-METHYL-3H]- AF-DX 384, [2,3-DIPROPYLAMINO-3H]-

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5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE LS 75 11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one 5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one AK-36728 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro- 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro- 1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine Pirenzepine EP Impurity B 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one 885-70-1