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Chlorguanide Hydrochloride

Chlorguanide Hydrochloride Structure
Chlorguanide Hydrochloride structure
CAS No.
637-32-1
Chemical Name:
Chlorguanide Hydrochloride
Synonyms
m4888;3359rp;diguanyl;Paludrin;sn12,837;Chlorguanid;Chloroquanil;Proguanil HCL;ChlorguanideHCl;PROGUANIL HCL IP/BP
CBNumber:
CB5488955
Molecular Formula:
C11H17Cl2N5
Molecular Weight:
290.19
MDL Number:
MFCD01732193
MOL File:
637-32-1.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06
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Chlorguanide Hydrochloride Properties

Melting point 249-2510C
storage temp. 2-8°C
solubility acetonitrile: water: ~1mg/mL (60/40)
form solid
EWG's Food Scores 1
FDA UNII R71Y86M0WT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P330+P331+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  3249
WGK Germany  3
RTECS  DU1750000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2925294500
Toxicity LD50 orally in rats: 200 mg/kg (Schmidt)

Chlorguanide Hydrochloride price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich G7048 Proguanil hydrochloride ≥95% (HPLC) 637-32-1 10mg $90 2024-03-01 Buy
Sigma-Aldrich 1568040 Proguanil hydrochloride United States Pharmacopeia (USP) Reference Standard 637-32-1 200mg $393 2024-03-01 Buy
Sigma-Aldrich BP297 Proguanil hydrochloride British Pharmacopoeia (BP) Reference Standard 637-32-1 100MG $221 2023-06-20 Buy
Sigma-Aldrich PHR1713 Proguanil hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 637-32-1 1g $173 2024-03-01 Buy
Sigma-Aldrich G7048 Proguanil hydrochloride ≥95% (HPLC) 637-32-1 50mg $341 2024-03-01 Buy
Product number Packaging Price Buy
G7048 10mg $90 Buy
1568040 200mg $393 Buy
BP297 100MG $221 Buy
PHR1713 1g $173 Buy
G7048 50mg $341 Buy

Chlorguanide Hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug.

Uses

Chlorguanide Hydrochloride can be intended for use as an internal standard for the quantification of Proguanil by GC- or LC-mass spectrometry.

brand name

Paludrine (Zeneca).

General Description

Proguanil hydrochloride is a biguanide compound, widely used as an antimalarial drug. It exhibits sporontocidal activity, thereby rendering the gametocytes non-infective to the mosquito vector.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biochem/physiol Actions

Chlorguanide (proguanil) is combined with atovaquone for malaria prophylaxis. The two compounds act synergistically to inhibit the plasmodial dihydrofolate reductase (DHFR) and interrupt the electron transport chain. Mutations in DHFR account for the development of resistant strains.

Chlorguanide Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Chlorguanide Hydrochloride Suppliers

Global( 123)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Xi'an MC Biotech, Co., Ltd. 		029-89275612 +8618991951683 mcbio_sales@163.com China 2255 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 29271 58
AFINE CHEMICALS LIMITED 		0571-85134551 info@afinechem.com CHINA 15377 58
Alfa Chemistry 		+1-5166625404 Info@alfa-chemistry.com United States 21317 58
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8073 58
Supplier Advantage
Career Henan Chemica Co 		58
Xi'an MC Biotech, Co., Ltd. 		58
Dideu Industries Group Limited 		58
AFINE CHEMICALS LIMITED 		58
Alfa Chemistry 		58
TargetMol Chemicals Inc. 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai TaoSu Biochemical Technology Co., Ltd. 58

View Lastest Price from Chlorguanide Hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Chlorguanide Hydrochloride USP/EP/BP pictures 2021-06-18 Chlorguanide Hydrochloride USP/EP/BP
637-32-1
 US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited

637-32-1(Chlorguanide Hydrochloride)Related Search:

Proguanil Related Compound D (25 mg) (1,5-bis(1-methylethyl)biguanide hydrochloride) 1-(3-Chlorophenyl)-5-isopropylbiguanide Hydrochloride Proguanil Related Compound C (25 mg) (1,5-bis(4-chlorophenyl)biguanide hydrochloride) 1-Cyano-3-isopropylguanidine Levetiracetam
Gemfibrozil GEMFIBROZIL RELATED COMPOUND A (20 MG) (2,2-DIMETHYL-5-[2,5-DIMETHYL-4-(PROPENE-1-YL)PHE-NOXY]VALERIC ACID) PROGUANIL HYDROCHLORIDE - REFERENCE SPECTRUM PROGUANIL HYDROCHLORIDE IMP. B (EP): 4-CHLOROANILINE GEMFIBROZIL IMPURITY A
PROGUANIL HYDROCHLORIDE 1-(4-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE N-(4-CHLOROPHENYL)-N'-(ISOPROPYL)-IMIDODICARBONIMIDIC DIAMIDE Chlorguanide Hydrochloride

1of3

Chloroquanil Proguanil Hydrochloride (200 mg) IMidodicarboniMidic diaMide, N-(4-chlorophenyl)-N'-(1-Methylethyl) -, Hydrochloride (1:1) Proguanil HCL ChlorguanideHCl 1-(p-chlorophenyl)-5-isopropylbiguanidehydrochloride 1-(p-chlorophenyl)-5-isopropyl-biguanidmonohydrochloride 3359rp chlorguanidehydrochloride chloroguanidehydrochloride chloroguanidinehydrochloride diguanyl drinupalhydrochloride Chlorguanid N-(4-Chlorophenyl)-N'-(1-methylethyl)-imidodicarbonimidic Diamide Hydrochloride Paludrin Chlorguanide Hydrochloride3 N1-(4-Chlorophenyl)-N5-isopropylbiguanide PROGUANIL HYDROCHLORIDE###N-(4-CHLOROPHENYL)-N'-(ISOPROPYL)-IMIDODICARBONIMIDIC DIAMIDE guanatolhydrochloride m4888 n-4-chlorophenyl-n(sup5)-isopropyldiguanidehydrochloride paludrinehydrochloride palusilhydrochloride sn12,837 PROGUANIL HYDROCHLORIDE Biguanide, 1-(p-chlorophenyl)-5-isopropyl-, monohydrochloride Proguanil for system suitability 1-(4-Chlorophenyl)-5-(1-methylethyl)biguanide hydrochloride Chlorguanide Hydrochloride USP/EP/BP Proguanil Hydrochloride (1568040) N1-(4-Chlorophenyl)-N5-isopropylbiguanide Hydrochloride Proguanil hydrochloride,Proguanil,infection,biguanide,Inhibitor,embryotoxicity,toxicity,inhibit,Parasite,reproductive,antimalarial,Antifolate Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-,monohydrochloride PROGUANIL HCL IP/BP 637-32-1 C11H16ClN5HCl C11H17Cl2N5 Aromatics Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals PALUDRINE