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5-Methyltetrahydrofolic acid

CAS No.
134-35-0
Chemical Name:
5-Methyltetrahydrofolic acid
Synonyms
MethylFolate;5-methyltetrahydrofolate;methyl-THF;5-METHYL-THF;5-Methyl-5,6,7,8-tetrahydrofolic acid;5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate;methyl-H4F;Prefolic A;n5-CH3-THF;methyl acid
CBNumber:
CB5500949
Molecular Formula:
C20H25N7O6
Molecular Weight:
459.46
MDL Number:
MFCD00900533
MOL File:
134-35-0.mol
MSDS File:
SDS
Last updated:2024-04-08 13:48:25

5-Methyltetrahydrofolic acid Properties

Melting point >300°C (dec.)
Density 1.62±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Aqueous Base (Slightly, Sonicated)
form Solid
pka 3.51±0.10(Predicted)
color Pale Beige
Stability Hygroscopic
FDA UNII TYK22LML8F
NCI Drug Dictionary L-methylfolate

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

5-Methyltetrahydrofolic acid price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16159 5-Methyltetrahydrofolic Acid ≥98% 134-35-0 5mg $158 2021-12-16 Buy
Cayman Chemical 16159 5-Methyltetrahydrofolic Acid ≥98% 134-35-0 1mg $35 2021-12-16 Buy
Cayman Chemical 16159 5-Methyltetrahydrofolic Acid ≥98% 134-35-0 10mg $263 2021-12-16 Buy
Usbiological 017430 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate 134-35-0 10mg $446 2021-12-16 Buy
TRC M338145 N-MethyltetrahydrofolicAcid 134-35-0 1g $85 2021-12-16 Buy
Product number Packaging Price Buy
16159 5mg $158 Buy
16159 1mg $35 Buy
16159 10mg $263 Buy
017430 10mg $446 Buy
M338145 1g $85 Buy

5-Methyltetrahydrofolic acid Chemical Properties,Uses,Production

Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

Supplements

5-Methyltetrahydrofolic acid is a biologically active form of folic acid. 5-Methyltetrahydrofolic acid is a methylated derivate of tetrahydrofolate. 5-Methyltetrahydrofolic acid is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

Mechanism of Action

Prefolic A, also known as 5-Methyltetrahydrofolate, is a biologically active form of folic acid that functions, in conjunction with vitamin B12, as a methyl-group donor involved in the conversion of homocysteine to methionine. Methyl folate is an active metabolite of folic acid. Vitamin supplement in health care products.

Shipping & Storage Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Stored in dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).Shelf Life can be more than 2 years if stored properly.

Chemical Properties

Off-White Solid

Uses

5-Methyltetrahydrofolic acid is a metabolite of Folic acid; inhibits photosensitization reactions and strand breaks in DNA. 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

Uses

5-Methyltetrahydrofolic acid-(glutamic acid-13C5) can be used as a stable isotope internal standard for accurate data interpretation in citrus juice samples by LC-MS.

General Description

5-Methyltetrahydrofolic acid (5-MTHF) is an active folate metabolite. It plays an important role in the synthesis of methionine from homocysteine by donating methyl group.
5-Methyltetrahydrofolic acid-(glutamic acid-13C5) is an isotope of vitamin B9 wherein all the five glutamate carbons are replaced by 13C6 carbon.

5-Methyltetrahydrofolic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 141)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Nanjing Gold Pharmaceutical Technology Co. Ltd.
025-84209270 15906146951 CHINA 115 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Biochempartner
0086-13720134139 candy@biochempartner.com CHINA 967 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 2995 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58

Related articles

View Lastest Price from 5-Methyltetrahydrofolic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
methyl folate pictures 2024-04-08 methyl folate
134-35-0
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
5-Methyltetrahydrofolic acid pictures 2023-08-31 5-Methyltetrahydrofolic acid
134-35-0
US $100.00 / bag 1bag 99 5000 Hebei Fengqiang Trading Co., LTD
5-Methyltetrahydrofolic acid pictures 2023-08-29 5-Methyltetrahydrofolic acid
134-35-0
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
  • methyl folate pictures
  • methyl folate
    134-35-0
  • US $0.00-0.00 / Kg
  • 99.9%
  • airuikechemical co., ltd.
5-Methyltetrahydropteroyl monoglutamate 5-Methyltetrahydropteroylglutamic acid N5-Methyltetrahydropteroylglutamate N-Methyltetrahydrofolate N-Methyltetrahydrofolic acid Prefolic A L-Methyl Folate 5-methyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid methyl-H4F n5-methyltetrahydrofolate N5-methyltetrahydropteroyl mono-L-glutamate N5-methyl-THF 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Mixture of Diastereomers) 5-Methyltetrahydrofolic Acid Calcium Salt Trihydrate (Also See: L375720) N-[4-[[(2-AMino-3,4,5,6,7,8-hexahydro-5-Methyl-4-oxo-6-pteridinyl)Methyl]aMino]benzoyl]-L-glutaMic Acid CalciuM Trihydrate N5-Methyl tetrahydrofolic acid METHYL FOLATE(METAFOLIN)(P) 2-[4-[(2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]aminopentanedioic acid n5-CH3-THF METHYLTETRAHYDROFOLICACID 5-methyl-5,6,7,8-tetrahydrofolate N-[4-[[(2-Amino-1,4-dihydro-4-oxopteridin)-6-ylmethyl]amino]benzoyl]-L-glutamic acid 5-methyl ester 5-METHYLTETRAHYDROFOLIC ACID methyl acid (2S)-2-(4-(((2-Amino-5-methyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid 5-Methyltetrahydrofolate (mixture of diastereomers) L-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]- Folic Acid Impurity 36 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) 99 atom % 13C, 95% (CP) 5-Methyltetrahydrofolic acid-(glutamic acid-13C5) 5-methyltetrahydrofolicaci 5-Methyltetrahydrofolic acid 1mg/ml in water L-methylfolate Methyl Folate 5-methyltetrahydrofolate MethylFolate 5-Methyl-5,6,7,8-tetrahydrofolic acid 5-METHYL-THF methyl-THF 5-Methyltetrahydrofolic Acid CalciuM Salt Trihydrate 5-Methylterahydrofolic acid 134-35-0 C20H29CaN7O9 C20H20N7O6 Bases & Related Reagents Heterocycles Intermediates & Fine Chemicals Metabolites & Impurities Nucleotides Pharmaceuticals