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ERYTHROMYCIN LACTOBIONATE (200 MG)

CAS No.
3847-29-8
Chemical Name:
ERYTHROMYCIN LACTOBIONATE (200 MG)
Synonyms
Erythromycin lactobionate;Erythrocin lactobionate;ERYTHROMYCIN LACTOBIONATE USP(CRM STANDARD);Lactose azithroMycin;Erythomycin lactobionate;Azithromycin lactobionate;Moxifloxacin Impurity 146;Erythromycin lactobionate CRS;ERYTHROMYC LACTOBIONATE (200 MG);ERYTHROMYCIN LACTOBIONATE (200 MG)
CBNumber:
CB5501658
Molecular Formula:
C37H67NO13.C12H22O12
Molecular Weight:
1092.22
MDL Number:
MOL File:
3847-29-8.mol
Last updated:2023-05-18 11:31:06

ERYTHROMYCIN LACTOBIONATE (200 MG) Properties

Melting point 145-150°
Density 0.9083 (rough estimate)
refractive index 1.5300 (estimate)
storage temp. Refrigerator
solubility Soluble in water, freely soluble in anhydrous ethanol and in methanol, very slightly soluble in acetone and in methylene chloride.
form Solid
color White to Off-White
Water Solubility >20g/L(21 ºC)
FDA UNII 33H58I7GLQ

SAFETY

Risk and Safety Statements

HS Code  2941500000

ERYTHROMYCIN LACTOBIONATE (200 MG) price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17189 Erythromycin lactobionate 3847-29-8 1g $57 2024-03-01 Buy
Cayman Chemical 17189 Erythromycin lactobionate 3847-29-8 5g $243 2024-03-01 Buy
Cayman Chemical 17189 Erythromycin lactobionate 3847-29-8 500mg $32 2024-03-01 Buy
Cayman Chemical 17189 Erythromycin lactobionate 3847-29-8 10g $426 2024-03-01 Buy
TRC E650040 ErythromycinLactobionate 3847-29-8 500mg $215 2021-12-16 Buy
Product number Packaging Price Buy
17189 1g $57 Buy
17189 5g $243 Buy
17189 500mg $32 Buy
17189 10g $426 Buy
E650040 500mg $215 Buy

ERYTHROMYCIN LACTOBIONATE (200 MG) Chemical Properties,Uses,Production

Description

Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.

Chemical Properties

White or slightly yellow hygroscopic, powder.

Originator

Erythrocin,Abbott,US,1954

Uses

Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.

Uses

Macrolide antibacterial.

Manufacturing Process

A solution of erythromycin free base is prepared by dissolving 8.0 grams of erythromycin in 25 cc of acetone. 4.0 grams of lactobiono-delta-lactone is dissolved in 25 cc of water. The free lactobionic acid is formed in this solution and it has the molecular formula C12H22O12. The two solutions are mixed and evaporated to a gummy residue. This residue is dissolved in 60 cc of water and the solution is frozen and dried in vacuum by lyophilization. The dried residue of erythromycin lactobionate is a white amorphous powder and weighs 11.7 grams. The reaction product has an activity against B. subtilis of 420units per milligram. Its solubility in water is about 200 mg/cc and the melting point of the white powdery reaction product is 145° to 150°C.

brand name

Erythrocin (Abbott); Erythrocin (Hospira).

Therapeutic Function

Antibacterial

General Description

Erythromycin lactobionate is a water-soluble salt preparedby reacting erythromycin base with lactobiono-σ-lactone. Itoccurs as an amorphous powder that is freely soluble inwater and alcohol and slightly soluble in ether. It is intended,after reconstitution in sterile water, for intravenousadministration to achieve high plasma levels in the treatmentof serious infections.

ERYTHROMYCIN LACTOBIONATE (200 MG) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 123)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682 bruce@xrdchem.cn CHINA 566 55
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3581 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9320 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29220 58

View Lastest Price from ERYTHROMYCIN LACTOBIONATE (200 MG) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Erythromycin lactobionate pictures 2021-11-17 Erythromycin lactobionate
3847-29-8
US $0.00-0.00 / Kg/Drum 1KG 98%min 1000kgs WUHAN FORTUNA CHEMICAL CO., LTD
ErythroMycin Lactobionate pictures 2021-07-20 ErythroMycin Lactobionate
3847-29-8
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
Erythromycin lactobionate pictures 2021-07-13 Erythromycin lactobionate
3847-29-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Erythromycin, Lactobionate Salt-N,N-dimethyl-13C2 D-Gluconic acid, 4-O-β-D-galactopyranosyl-, compd. with erythromycin (1:1) (9CI) Erythromycin, 4-O-β-D-galactopyranosyl-D-gluconate (salt) Erythromycin, compd. with lactobionic acid (7CI) Erythromycin, lactobionate (1:1) (salt) Lactobionic acid, compd. with erythromycin (1:1) (8CI) Azithromycin lactobionate 4-o-beta-d-galactopyranosyl-d-gluconic aci compd. with erythromycin Erythomycin lactobionate lactobionic acid, compd. with erythromycin (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-Dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione (2R, Lactose azithroMycin ERYTHROMYCIN LACTOBIONATE (200 MG) 4-o-beta-d-galactopyranosyl-d-gluconicacicompd.witherythromycin(1:1) 4-o-beta-d-galactopyranosyl-d-gluconicacidcompd.witherythromycin erythromycinmono(4-o-beta-d-galactopyranosyl-d-gluconate)(salt) lactobionicacid,compd.witherythromycin(1:1) Erythromycin lactobionate CRS ERYTHROMYC LACTOBIONATE (200 MG) ERYTHROMYCIN LACTOBIONATE (200 MG) USP/EP/BP ERYTHROMYCIN LACTOBIONATE USP/EP/BP Erythromycin Lactobionate (1247003) ERYTHROMYCIN LACTOBIONATE USP(CRM STANDARD) Erythrocin lactobionate Erythromycin lactobionate Moxifloxacin Impurity 146 3847-29-8 C49H87NO24 CC48H89NO25 C2C47H89NO25 C49H89NO25 API Peptide Synthesis/Antibiotics