TG003
- CAS No.
- 300801-52-9
- Chemical Name:
- TG003
- Synonyms
- CS-955;CS-1704;(E/Z)-TG003;TG003/TG-003;TG003 USP/EP/BP;Cdc2-Like Kinase Inhibitor, TG003;1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone;2-Propanone,1-(3-ethyl-5-Methoxy-2(3H)-benzothiazolylidene)-;1-(3-Ethyl-5-methoxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one;(1Z)-1-(3-Ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one
- CBNumber:
- CB5505045
- Molecular Formula:
- C13H15NO2S
- Molecular Weight:
- 249.33
- MDL Number:
- MFCD00624584
- MOL File:
- 300801-52-9.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
TG003 price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T5575 | TG003 ≥98% (HPLC) | 300801-52-9 | 5mg | $196 | 2024-03-01 | Buy |
| Sigma-Aldrich | T5575 | TG003 ≥98% (HPLC) | 300801-52-9 | 25mg | $778 | 2024-03-01 | Buy |
| Alfa Aesar | J64690 | Cdc2-Like Kinase Inhibitor, TG003 | 300801-52-9 | 5mg | $85.1 | 2023-06-20 | Buy |
| Alfa Aesar | J64690 | Cdc2-Like Kinase Inhibitor, TG003 | 300801-52-9 | 50mg | $551 | 2023-06-20 | Buy |
| Cayman Chemical | 10398 | TG003 ≥95% | 300801-52-9 | 1mg | $23 | 2024-03-01 | Buy |
TG003 Chemical Properties,Uses,Production
Description
Cdc2-
Uses
TG003 can be used as a potent CDC-2 kinase inhibitor, allowing for research into identification of signaling pathways and possible therapeutic treatments.
Uses
Cdc2-Like Kinase Inhibitor, TG003 is a benzothiazole agent that acts as a specific and ATP-competitive inhibitor of Clk family members. Reports show that TG003 modifies the regulation of alternative splicing modulated by phosphorylation of SR proteins in vitro, and rescues defects in the development of Xenopus caused by an overabundance of Clk activity.
Uses
TG003 has been used in PAC1 cell culture and in vitro kinase assays.
Biochem/physiol Actions
TG003, a CLK (cdc2-like kinase) family inhibitor is used as a drug for duchenne muscular dystrophy.
TG003 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 |