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Tauro-α-muricholic acid sodium salt

Tauro-α-muricholic acid sodium salt Structure
Tauro-α-muricholic acid sodium salt structure
CAS No.
2260905-08-4
Chemical Name:
Tauro-α-muricholic acid sodium salt
Synonyms
2-[[(3α,5β,6β,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonicacid,monosodiumsalt
CBNumber:
CB55985161
Molecular Formula:
C26H46NNaO7S
Molecular Weight:
539.7
MDL Number:
MOL File:
2260905-08-4.mol
Last updated:2023-05-21 10:59:17
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Tauro-α-muricholic acid sodium salt Properties

storage temp. Store at -20°C
solubility DMF: 10 mg/mL; DMSO: 10 mg/mL; DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL; Ethanol: 1 mg/mL
form A crystalline solid

Tauro-α-muricholic acid sodium salt price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 20288 Tauro-α-muricholic Acid (sodium salt) 2260905-08-4 1mg $158 2024-03-01 Buy
Product number Packaging Price Buy
20288 1mg $158 Buy

Tauro-α-muricholic acid sodium salt Chemical Properties,Uses,Production

Description

Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid .1 TαMCA is common in rodents but has also been found in small amounts in human serum.2

References

1. Sayin, S.I., Wahlstr?m, A., Felin, J., et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist Cell Metab. 17(2),225-235(2013).
2. García-Ca?averas, J.C., Donato, M.T., Castell, J.V., et al. Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method J. Lipid Res. 53(10),2231-2241(2012).

Tauro-α-muricholic acid sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

Tauro-α-muricholic acid sodium salt Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Suzhou Haiben Pharmaceutical Co., Ltd 14760821013 14760821013 1816280386@qq.com China 8068 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
Supplier Advantage
BOC Sciences 65
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Suzhou Haiben Pharmaceutical Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
2-[[(3α,5β,6β,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonicacid,monosodiumsalt 2260905-08-4