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(±)-trans-GK563

(±)-trans-GK563 Structure
(±)-trans-GK563 structure
CAS No.
2351820-19-2
Chemical Name:
(±)-trans-GK563
Synonyms
(±)-trans-GK563;2-Oxetanone, 3-(4-phenylbutyl)-4-propyl-, (3R,4R)-rel-
CBNumber:
CB56197338
Molecular Formula:
C16H22O2
Molecular Weight:
246.34
MDL Number:
MOL File:
2351820-19-2.mol
Last updated:2023-05-21 10:59:17
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(±)-trans-GK563 Properties

Boiling point 364.2±11.0 °C(Predicted)
Density 1.010±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Chloroform: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble

(±)-trans-GK563 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth BG168610 GK 563 2351820-19-2 10mg $145 2021-12-16 Buy
Biosynth Carbosynth BG168610 GK 563 2351820-19-2 50mg $435 2021-12-16 Buy
Product number Packaging Price Buy
BG168610 10mg $145 Buy
BG168610 50mg $435 Buy

(±)-trans-GK563 Chemical Properties,Uses,Production

Description

trans-(±)-GK563 is a potent β-lactone inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (GVIA iPLA2; IC50 = 1 nM).1 It is selective for GVIA iPLA2 over GVIA cPLA2 (IC50 = 22 μM). trans-(±)-GK563 (1 and 10 μM) inhibits apoptosis induced by IL-1β and IFN-γ in INS-1 β-cells.

References

1. Dedaki, C., Kokotou, M.G., Mouchlis, V.D., et al. β-Lactones: A novel class of Ca2+-independent phospholipase A2 (group VIA iPLA2) inhibitors with the ability to inhibit β-cell apoptosis J. Med. Chem. 62(6),2916-2927(2019).

(±)-trans-GK563 Preparation Products And Raw materials

Raw materials

Preparation Products

(±)-trans-GK563 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
(±)-trans-GK563 2-Oxetanone, 3-(4-phenylbutyl)-4-propyl-, (3R,4R)-rel- 2351820-19-2