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2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID

CAS No.
64118-84-9
Chemical Name:
2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonyms
4-HYDROXY DICLOFENAC;4-OHD;4'-OHD;Hydroxydiclofenac;4-HYDROXY DICLOFEC;4'-HYDROXYDICLOFENAC;Diclofenac Impurity 15;DICLOFENAC, 4'-HYDROXY-;4'-HYDROXYDICLOFENAC STANDARD;4′-Hydroxydiclofenac solution
CBNumber:
CB5672615
Molecular Formula:
C14H11Cl2NO3
Molecular Weight:
312.15
MDL Number:
MFCD01671980
MOL File:
64118-84-9.mol
Last updated:2023-06-08 09:01:57

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Properties

Melting point 178-185°C dec.
Boiling point 432.7±45.0 °C(Predicted)
Density 1.520±0.06 g/cm3(Predicted)
Flash point 2℃
storage temp. -20°C
solubility Soluble in DMSO, ethanol or methanol
pka 4.17±0.10(Predicted)
BRN 4198042
Stability Light Sensitive
FDA UNII NJF5O599EF

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H301-H315-H318-H335-H410
Precautionary statements  P261-P273-P280-P301+P310-P302+P352-P305+P351+P338
Hazard Codes  T,N,Xn,F
Risk Statements  25-37/38-41-50/53-36-20/21/22-11
Safety Statements  26-39-45-60-61-36/37-16
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  AG6542800
HazardClass  6.1
NFPA 704
0
3 0

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H3661 4′-Hydroxydiclofenac ≥98% (HPLC) 64118-84-9 1vial $1440 2024-03-01 Buy
Sigma-Aldrich H-052 4′-Hydroxydiclofenac solution 100?μg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant? 64118-84-9 1mL $369 2024-03-01 Buy
Sigma-Aldrich 32412 4′-Hydroxydiclofenac VETRANAL , analytical standard 64118-84-9 10mg $888 2024-03-01 Buy
Alfa Aesar J64095 4'-Hydroxydiclofenac 64118-84-9 5mg $540.65 2024-03-01 Buy
Cayman Chemical 10008518 4-hydroxy Diclofenac ≥97% 64118-84-9 1mg $117 2024-03-01 Buy
Product number Packaging Price Buy
H3661 1vial $1440 Buy
H-052 1mL $369 Buy
32412 10mg $888 Buy
J64095 5mg $540.65 Buy
10008518 1mg $117 Buy

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Chemical Properties,Uses,Production

Description

4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE2 synthesis, it demonstrates anti-inflammatory and analgesic properties.

Chemical Properties

Light Violet Solid

Uses

A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac

Uses

A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.

Uses

A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor

Definition

ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.

General Description

4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.

2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 88)Suppliers
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Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Standardpharm Co. Ltd.
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CONIER CHEM AND PHARMA LIMITED
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TargetMol Chemicals Inc.
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sgtlifesciences pvt ltd
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Alfa Chemistry
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China National Standard Pharmaceutical Corporation Limited
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Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
(o-(2,6-dichloro-4-hydroxyanilino)phenyl)-aceticaci (o-(2,6-dichloro-4-hydroxyanilino)phenyl)aceticacid DICLOFENAC, 4'-HYDROXY- 4'-OHD 4-OHD 4'-HYDROXYDICLOFENAC 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID 4'-HYDROXYDICLOFENAC STANDARD [2-(2,6-Dichloro-4-hydroxyanilino)phenyl]acetic acid 2-(2,6-Dichloro-4-hydroxyanilino)benzeneacetic acid Benzeneacetic acid, 2-[(2,6-dichloro-4-hydroxyphenyl)aMino]- Hydroxydiclofenac 4′-Hydroxydiclofenac solution 4'-Hydroxydiclofenac VETRANAL(TM), analytical standard Diclofenac Impurity 15 2-(2-((2,6-dichloro-4-hydroxyphenyl)amino)phenyl)acetic acid 4-HYDROXY DICLOFENAC 4-HYDROXY DICLOFEC 64118-84-9 HU - HZ Analytical Standards Analytical Chromatography Product Catalog Alphabetic Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals