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Azamethiphos

Description References
Azamethiphos
Azamethiphos structure
CAS No.
35575-96-3
Chemical Name:
Azamethiphos
Synonyms
snip;SNIP(R);GS 40616;ALFACRON;SNIP(TM);cga18809;Salmosan;Alfracron;azametifos;ALFACRON(R)
CBNumber:
CB5687123
Molecular Formula:
C9H10ClN2O5PS
Formula Weight:
324.68
MOL File:
35575-96-3.mol

Azamethiphos Properties

Melting point:
88-93°C
Boiling point:
428.8±55.0 °C(Predicted)
Density 
1.566±0.06 g/cm3(Predicted)
vapor pressure 
4.9 x 10-6 Pa (20 °C)
storage temp. 
APPROX 4°C
Water Solubility 
1100 mg l-1 (20 °C)
form 
Solid
pka
0.94±0.20(Predicted)
CAS DataBase Reference
35575-96-3(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
9440R8149U
NIST Chemistry Reference
Phosphorothioic acid, s-[(6-chloro-2-oxooxazolo[4,5-b]pyridin-3(2h)-yl)methyl] o,o-dimethyl ester(35575-96-3)
EPA Substance Registry System
Azamethiphos (35575-96-3)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338-P264-P280i-P301+P312a-P337+P313-P501a
Hazard Codes  Xn
Risk Statements  22-36-40-21-67-36/37/38
Safety Statements  26-36/37-24/25-23
RIDADR  UN 1593 6.1/PG 3
WGK Germany  3
RTECS  TE8070000
HS Code  29349990
Toxicity LD50 orl-rat: 1180 mg/kg PEMNDP 9,44,91

Azamethiphos price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 45331 Azamethiphos PESTANAL 35575-96-3 250mg $52.3 2020-08-18 Buy
Alfa Aesar H66105 S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% 35575-96-3 1g $72.7 2020-06-24 Buy
Alfa Aesar H66105 S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% 35575-96-3 5g $332 2020-06-24 Buy
Alfa Aesar H66105 S-[(6-Chloro-2-oxooxazolo[4,5-b]pyridin-3yl)methyl] O,O-dimethyl phosphorothioate, 95% 35575-96-3 250mg $23.1 2020-06-24 Buy

Azamethiphos Chemical Properties,Uses,Production

Description

Azamethiphos is an organothiophosphate insecticide. It can be used as a veterinary drug used in the salmon fish farming for controlling parasites such as salmon lice (Lepeophtheirus salmonis), a marine ectoparasitic copepod on salmonid species. Its primary target is on the acetylcholinesterase, a serine hydrolase involved in neurotransmission at cholinergic synapses and neuromuscular junctions.

References

Intorre, L, et al. "Safety of azamethiphos in eel, seabass and trout." Pharmacological Research the Official Journal of the Italian Pharmacological Society 49.2(2004):171. Kaur, K, et al. "Mechanism behind Resistance against the Organophosphate Azamethiphos in Salmon Lice (Lepeophtheirus salmonis). " Plos One 10.4(2015):e0124220.

Chemical Properties

white to light yellow crystal powde

Uses

Azamethiphos is used to control flies and other insect pests in animal houses and also public hygiene and health pests such as mosquitoes and cockroaches. It has recently been used to control sea lice in salmon.

Uses

Synergistic insecticidal and acaricidal organophosphorus compound

Safety Profile

Moderately toxic by ingestion andskin contact. When heated to decomposition it emits toxicvapors of NOx, SOx, POx, and Cl- .

Metabolic pathway

Azamethiphos is metabolised in mammals via hydrolysis, followed by opening of the oxazolinone ring and conjugation of the resultant aminopyridinol as the glucuronide and sulfate ester.

Metabolism

Azamethiphos is metabolized via the cleavage of phosphorothiolate C?S bond, followed by N-demethylation and opening of the oxazolinone ring and conjugation of the resultant aminochloropyridinol as the glucuronide and sulfate ester.

Toxicity evaluation

Acute oral LD50 for rats is 1180 mg/kg. Inhalation LC50 (4 h) for rats is >560 mg/m3 air. ADI is 0.025 mg/kg.

Degradation

Azamethiphos is unstable in alkalis and acids. The DT50 values at pH 5,7 and 9 were 800,260 and 4.3 hours, respectively (PM).

Azamethiphos Preparation Products And Raw materials

Raw materials

Preparation Products


Azamethiphos Suppliers

Global( 214)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
+86 (576) 8169-6105 sales@frappschem.com China 886 50
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21869 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22623 55
PI & PI BIOTECH INC.
18371201331
020-81716319 Sales@pipitech.com CHINA 3048 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 568 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2754 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30037 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 10375 58
Chongqing Chemdad Co.,Ltd
+86-19923101450
sales@chemdad.com CHINA 4001 58

View Lastest Price from Azamethiphos manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-08-10 PHOSPHOROTHIOATE Hot sell
35575-96-3
US $1.50 / KG 1KG 99% 20tons Hebei Runbin Biotechnology Co. LTD
2018-12-20 Azamethiphos
35575-96-3
US $1.00 / kg 1kg 99% Customized career henan chemical co

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